Results 21 to 30 of about 1,704,518 (313)

Barriers to Care [PDF]

The Canadian Journal of Psychiatry, 1984
In elevating cost containment to a first principle, the current political debate about health policy in the U.S. and Canada has lost sight of what should be its primary concern: the health status of the population. The two need not be incompatible. Many current medical procedures are of uncertain value for health and entail sizable costs.
openaire   +2 more sources

Spatiotemporal resolution of spinal meningeal and parenchymal inflammation during experimental autoimmune encephalomyelitis

Neurobiology of Disease, 2017
Experimental autoimmune encephalomyelitis (EAE) induced by active immunization of C57BL/6 mice with peptide from myelin oligodendrocyte protein (MOG35–55), is a neuroinflammatory, demyelinating disease widely recognized as an animal model of multiple ...
Bandana Shrestha, Xi Jiang, Shujun Ge, Debayon Paul, Peter Chianchiano, Joel S. Pachter   +5 more
doaj   +1 more source

Cholesterol sulfate fluidizes the sterol fraction of the stratum corneum lipid phase and increases its permeability

Journal of Lipid Research, 2022
Desulfation of cholesterol sulfate (CholS) to cholesterol (Chol) is an important event in epidermal homeostasis and necessary for stratum corneum (SC) barrier function.
Ferdinand Fandrei, Oskar Engberg, Lukáš Opálka, Pavla Jančálková, Petra Pullmannová, Miloš Steinhart, Andrej Kováčik, Kateřina Vávrová, Daniel Huster   +8 more
doaj   +1 more source

Establishing an Apheresis Medicine Program in a Resource‐Constrained Setting: A 5‐Year Experience From Lagos, Nigeria

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Rasheed A. Balogun   +4 more
wiley   +1 more source

Impacts of foodborne inorganic nanoparticles on the gut microbiota-immune axis: potential consequences for host health

Particle and Fibre Toxicology, 2020
Background In food toxicology, there is growing interest in studying the impacts of foodborne nanoparticles (NPs, originating from food additives, food supplements or food packaging) on the intestinal microbiome due to the important and complex ...
Bruno Lamas, Natalia Martins Breyner, Eric Houdeau   +2 more
doaj   +1 more source

Important ecosystem function, low redundancy and high vulnerability: The trifecta argument for protecting the Great Barrier Reef's tabular Acropora

Conservation Letters, 2021
Identifying organisms that play an important role in maintaining ecosystem function is a key aspect of resilience‐based management. For Australia's Great Barrier Reef (GBR), we found that the recovery ability of shallow exposed fore‐reefs is more than 14
Juan C. Ortiz, Rachel J. Pears, Roger Beeden, Jen Dryden, Nicholas H. Wolff, Maria del C. Gomez Cabrera, Peter J Mumby   +6 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Compilation of information on the interaction of reef sharks with the reef line fishery in the Great Barrier Reef Marine Park: final report to the Great Barrier Reef Marine Park Authority [PDF]

, 2008
[Extract] Three data sets were examined to define the level of interaction of reef associated sharks with the commercial Coral Reef Fin Fish Fishery (CRFFF) within the Great Barrier Reef. Data were examined from; 1) fishery logbooks from 1989-2006; 2) an
Welch, D.J., Ballagh, A., Simpfendorfer, C.A., Mapstone, B.D., Heupel, M.R., Williams, A.J.   +5 more
core  

Butyrate administration is not sufficient to improve immune reconstitution in antiretroviral-treated SIV-infected macaques

Scientific Reports, 2022
Defective gastrointestinal barrier function and, in turn, microbial translocation have been identified as significant contributors to persistent inflammation in antiretroviral (ARV)-treated people living with HIV. Metabolic supplementation of short-chain
Alexandra M. Ortiz, Jennifer Simpson, Charlotte A. Langner, Phillip J. Baker, Cynthia Aguilar, Kelsie Brooks, Jacob K. Flynn, Carol L. Vinton, Andrew R. Rahmberg, Heather D. Hickman, Jason M. Brenchley   +10 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source