Results 21 to 30 of about 3,473,869 (204)

Human ES-derived MSCs correct TNF-α-mediated alterations in a blood–brain barrier model

Fluids and Barriers of the CNS, 2019
Background Immune cell trafficking into the CNS is considered to contribute to pathogenesis in MS and its animal model, EAE. Disruption of the blood–brain barrier (BBB) is a hallmark of these pathologies and a potential target of therapeutics.
Shujun Ge, Xi Jiang, Debayon Paul, Li Song, Xiaofang Wang, Joel S. Pachter   +5 more
doaj   +1 more source

Permeability Barrier and Microstructure of Skin Lipid Membrane Models of Impaired Glucosylceramide Processing

Scientific Reports, 2017
Ceramide (Cer) release from glucosylceramides (GlcCer) is critical for the formation of the skin permeability barrier. Changes in β-glucocerebrosidase (GlcCer’ase) activity lead to diminished Cer, GlcCer accumulation and structural defects in SC lipid ...
Michaela Sochorová, Klára Staňková, Petra Pullmannová, Andrej Kováčik, Jarmila Zbytovská, Kateřina Vávrová   +5 more
doaj   +1 more source

Origine et destination du soin medical

Ocula, 2019
Defining the user as both professional and beneficiary, I propose a systemic and participative modelling of project management. This means, in the field of medical care, that the patient is both at the beginning and at the end of the process and that he ...
Philippe Barrier
doaj   +1 more source

Les exemples dans l’élaboration des démonstrations mathématiques : une approche sémantique et dialogique

Recherches en Éducation, 2016
This paper addresses the roles of examples when dealing with mathematical proof in higher education. I use the distinction between semantic and syntactic approaches to get a first insight.
Thomas Barrier
doaj   +1 more source

Spatiotemporal resolution of spinal meningeal and parenchymal inflammation during experimental autoimmune encephalomyelitis

Neurobiology of Disease, 2017
Experimental autoimmune encephalomyelitis (EAE) induced by active immunization of C57BL/6 mice with peptide from myelin oligodendrocyte protein (MOG35–55), is a neuroinflammatory, demyelinating disease widely recognized as an animal model of multiple ...
Bandana Shrestha, Xi Jiang, Shujun Ge, Debayon Paul, Peter Chianchiano, Joel S. Pachter   +5 more
doaj   +1 more source

RETRACTED ARTICLE: Secretome of endothelial progenitor cells from stroke patients promotes endothelial barrier tightness and protects against hypoxia-induced vascular leakage

Stem Cell Research & Therapy, 2021
Background Cell-based therapeutic strategies have been proposed as an alternative for brain repair after stroke, but their clinical application has been hampered by potential adverse effects in the long term.
Rodrigo Azevedo Loiola, Miguel García-Gabilondo, Alba Grayston, Paulina Bugno, Agnieszka Kowalska, Sophie Duban-Deweer, Eleonora Rizzi, Johan Hachani, Yasuteru Sano, Fumitaka Shimizu, Takashi Kanda, Caroline Mysiorek, Maciej Piotr Mazurek, Anna Rosell, Fabien Gosselet   +14 more
doaj   +1 more source

Quantum Effects in Barrier Dynamics

, 1995
The dynamics near the top of a potential barrier is studied in the temperature region where quantum effects become important. The time evolution of the density matrix of a system that deviates initially from equilibrium in the vicinity of the barrier top
Ankerhold, Ankerhold, Caldeira, Caldeira, Calderia, Feynman, Feynman, Grabert, Grabert, Grabert, Grote, Hermann Grabert, Hänggi, Hänggi, Joachim Ankerhold, Miller, Miller, Miller, Schulman, Tanimura, Weiss, Wolynes, Yamamoto   +22 more
core   +1 more source

Conceptual barriers to understanding physical barriers [PDF]

Seminars in Cell & Developmental Biology, 2015
The members of the large family of claudin proteins regulate ion and water flux across the tight junction. Many claudins, e.g. claudins 2 and 15, accomplish this by forming size- and charge-selective paracellular channels. Claudins also appear to be essential for genesis of tight junction strands and recruitment of other proteins to these sites.
Amulya, Lingaraju, Tiha M, Long, Yitang, Wang, Jotham R, Austin, Jerrold R, Turner   +4 more
openaire   +2 more sources

Enquête de l’IEA sur le niveau en lecture - II

Revue Internationale d’Éducation de Sèvres, 1994
Dans cet article, l’auteur présente et analyse l’enquête sur la lecture réalisée par l’IEA en 1991, en commentant plus particulièrement les résultats concernant la France et l’influence des stratégies des maîtres en CM1.
Émilie Barrier
doaj   +1 more source

Mapping from quasi-elastic scattering to fusion reactions

, 2014
The fusion barrier distribution has provided a nice representation for the channel coupling effects on heavy-ion fusion reactions at energies around the Coulomb barrier.
Hagino, K., Rowley, N.
core   +4 more sources