Results 61 to 70 of about 1,704,518 (313)

Reef Beat education series: our Great Barrier Reef

open access: yes, 2003
In 2003, Reef Beat was developed as a curriculum-based education program for students who read the Newspapers in Education (NIE) lift out in local newspapers Townsville Bulletin and News Mail, the Daily Mercury. Newspaper editorials (feature articles) in

core   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Vulnerability of Great Barrier Reef plankton to climate change

open access: yes, 2007
Our approach here is to examine potential ways that climate change may alter plankton communities of the GBR in the future, focusing on the physical mechanisms that currently drive plankton productivity and composition.
Richardson, A. J.   +7 more
core  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Secretome of brain microvascular endothelial cells promotes endothelial barrier tightness and protects against hypoxia-induced vascular leakage

open access: yesMolecular Medicine
Cell-based therapeutic strategies have been proposed as an alternative for brain and blood vessels repair after stroke, but their clinical application is hampered by potential adverse effects.
Rodrigo Azevedo Loiola   +11 more
doaj   +1 more source

Une identité impériale sans Empire? Le sens de la politique de décolonisation britannique

open access: yesRevue LISA, 2007
Britain’s history as a nation and a great power cannot be dissociated from the concept of imperialism. The object of this article will be to study the way Britain managed to adapt her imperial identity to the post-colonial world that her own ...
Virginie Barrier-Roiron
doaj   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Reef Beat education series: the inshore Great Barrier Reef, bursting with biodiversity

open access: yes, 2012
The Great Barrier Reef Marine Park Authority's 2012 Reef Beat education series, the inshore Great Barrier Reef — bursting with biodiversity, explores how the inshore marine, coastal and Great Barrier Reef catchment ecosystems are interconnected and ...

core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

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