Results 81 to 90 of about 1,704,518 (313)

Chapter 23: Climate change and Great Barrier Reef: industries and communities

, 2007
Climate change is driving shifts in environmental conditions that, together with other human pressures, are impacting the Great Barrier Reef (GBR). Individuals, communities, and industries in the GBR catchment depend directly or indirectly on the GBR ...
Vella, K., Kelly, G., Innes, J., Fenton, M.   +3 more
core  

Paradoxes sur le public.

EspacesTemps.net, 2007
L’État contemporain ne se rapporte pas aux citoyens de manière individualisée et concrète, il les convoque plutôt comme une masse formelle et dépersonnalisée. Par une instrumentalisation de la culture et des arts, il en fait des consommateurs d’œuvres et
Thibaut Barrier
doaj  

Understanding fluctuating climate change risk perceptions through the lens of trust: a study of Great Barrier Reef region residents

npj Climate Action
Public perceptions of climate change risks are fundamental to public support for climate action. From a decade of surveying residents in the Great Barrier Reef region (2013–2023; n = 9920), we found that climate risk perceptions have fluctuated markedly,
Elizabeth V. Hobman, Matthew I. Curnock, Michelle Dyer, Cindy Huchery, Petina L. Pert, Emilee Chamberland, Aditi Mankad   +6 more
doaj   +1 more source

Breaking the Barrier

, 2018
Topical administration permits targeted, sustained delivery of therapeutics to human skin. Delivery to the skin, however, is typically limited to lipophilic molecules with molecular weight of < 500 Da, capable of crossing the stratum corneum. Nevertheless, there are indications protein delivery may be possible in barrier deficient skin, a condition ...
Giulbudagian, Michael, Yealland, Guy (Dr.), Hönzke, Stefan (Dr.), Edlich, Alexander (Dr.), Geisendörfer, Birte, Kleuser, Burkhard (Prof. Dr. rer. nat.), Hedtrich, Sarah (Prof. Dr.), Calderón, Marcelo   +7 more
openaire   +2 more sources

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Flood plumes in the Great Barrier Reef : spatial and temporal patterns in composition and distribution

, 2001
Protecting water quality in the Great Barrier Reef World Heritage Area is recognised as one of the major challenges facing management of the area.
Taylor, J., Brodie, J.E., Devlin, Michelle, Taylor, Jeremy, Waterhouse, Jane, Brodie, Jon, Devlin, M., Waterhouse, J.   +7 more
core  

Chapter 08: Vulnerability of seagrasses in the Great Barrier Reef to climate change [PDF]

, 2007
Seagrasses are flowering plants and, along with mangroves, have greater affinities to terrestrial plants than other marine macrophytes such as algae.
Udy, J., Grech, A., Waycott, M., McMahon, K., Collier, C., Ralph, P., McKenzie, L.J.   +6 more
core  

Application of a new MDCKII-MDR1 cell model to measure the extent of drug distribution in vitro at equilibrium for prediction of in vivo unbound brain-to-plasma drug distribution

Fluids and Barriers of the CNS
Intro: Reliable estimates of drug uptake from blood to brain parenchyma are crucial in CNS drug discovery and development. While in vivo Kp,uu,brain estimates are the gold standard for investigating brain drug disposition, animal usage is a limitation to
Kristine Langthaler, Christopher R. Jones, Lasse Saaby, Christoffer Bundgaard, Birger Brodin   +4 more
doaj   +1 more source

Shoulder–Elbow Joint Angle Prediction Using COANN with Multi-Source Information Integration

Applied Sciences
To address the precision challenges in upper-limb joint motion prediction, this study proposes a novel artificial neural network (COANN) enhanced by the Cheetah Optimization Algorithm (COA).
Siyu Zong, Wei Li, Dawen Sun, Zhuoda Jia, Zhengwei Yue   +4 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source