Results 121 to 130 of about 13,899,917 (351)

Peptide Bbeta(15-42) preserves endothelial barrier function in shock [PDF]

, 2009
Loss of vascular barrier function causes leak of fluid and proteins into tissues, extensive leak leads to shock and death. Barriers are largely formed by endothelial cell-cell contacts built up by VE-cadherin and are under the control of RhoGTPases. Here
Atrasheuskaya, Alena, Bukin, Eugenij, Friedl, Peter, Gröger, Marion, Hofer-Warbinek, Renate, Ignatyev, George, Knapp, Sylvia, Matt, Ulrich, Pasteiner, Waltraud, Petzelbauer, Peter, Reingruber, Sonja, Zacharowski, Kai, Zinkl, Daniela   +12 more
core  

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Effective collective barrier for magnetic relaxation in frozen ferrofluids

, 2003
Magnetic relaxation and frequency response were measured in frozen ferrimagnetic colloids of different concentrations. A crossover from reversible to irreversible behavior is observed for concentrated colloids.
Blatter, Denisov, Dormann, Eberbeck, Garanin, Griessen, Iglesias, Jonsson, Jonsson, Lottis, Luo, Maley, Mamiya, Mørup, Néel, Pazmandi, Prozorov, Prozorov, Prozorov, Ruslan Prozorov, Shafi, Stoner, Suslick, Suslick, Tanya Prozorov, Templeton, van Lierop, Yeshurun, Zeldov, Zhang   +29 more
core   +1 more source

Pili-like proteins of Akkermansia muciniphila modulate host immune responses and gut barrier function

PLoS ONE, 2017
Gut barrier function is key in maintaining a balanced response between the host and its microbiome. The microbiota can modulate changes in gut barrier as well as metabolic and inflammatory responses.
N. Ottman, J. Reunanen, M. Meijerink, T. Pietilä, V. Kainulainen, Judith Klievink, L. Huuskonen, S. Aalvink, M. Skurnik, S. Boeren, R. Satokari, A. Mercenier, A. Palva, H. Smidt, W. D. de Vos, C. Belzer   +15 more
semanticscholar   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Bacillus halotolerans SW207 alleviates enterotoxigenic Escherichia coli-induced inflammatory responses in weaned piglets by modulating the intestinal epithelial barrier, the TLR4/MyD88/NF-κB pathway, and intestinal microbiota

Microbiology Spectrum
Enterotoxigenic Escherichia coli (ETEC) is one of the major pathogens contributing to piglet diarrhea, with significant implications for both piglet health and the economic aspects of the livestock industry.
Minghan Li, Dongyu Zhao, Jialin Guo, Tianxu Pan, Tianming Niu, Yanqi Jiang, Chunwei Shi, Haibin Huang, Nan Wang, Di Zhang, Shumin Zhang, Chunfeng Wang, Guilian Yang   +12 more
doaj   +1 more source

Resonant reflection at magnetic barriers in quantum wires

, 2007
The conductance of a quantum wire containing a single magnetic barrier is studied numerically by means of the recursive Greens function technique. For sufficiently strong and localized barriers, Fano - type reflection resonances are observed close to the
B. L. Gallagher, Hengyi Xu, I. V. Zozoulenko, M. Evaldsson, S. Datta, S. Ihnatsenka, T. Heinzel   +6 more
core   +1 more source

Intestinal Barrier Function-Non-alcoholic Fatty Liver Disease Interactions and Possible Role of Gut Microbiota.

Journal of Agricultural and Food Chemistry, 2019
Non-alcoholic fatty liver disease (NAFLD) is a metabolic stress liver injury that is closely related to obesity, insulin resistance, type 2 diabetes, atherosclerosis, and metabolic syndrome.
Yizhe Cui, Qiuju Wang, R. Chang, Xiaocui Zhou, Chuang Xu   +4 more
semanticscholar   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Josephson effect in graphene SBS junctions

, 2007
We study Josephson effect in graphene superconductor- barrier- superconductor junctions with short and wide barriers of thickness $d$ and width $L$, which can be created by applying a gate voltage $V_0$ across the barrier region.
A. M. Zagoskin, H. B. Heersche, H.-J. Kown, I. O. Kulik, I. O. Kulik, K. Sengupta, Moitri Maiti   +6 more
core   +1 more source