Results 141 to 150 of about 13,899,917 (351)
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Detection of non-Gaussian Fluctuations in a Quantum Point Contact
, 2008 An experimental study of current fluctuations through a tunable transmission barrier, a quantum point contact, are reported. We measure the probability distribution function of transmitted charge with precision sufficient to extract the first three ...
E. V. Sukhorukov +4 more
core +2 more sources
Molecular Oncology, EarlyView.Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard +12 more
wiley +1 more source
Intestinal Mucosal Mast Cells: Key Modulators of Barrier Function and Homeostasis
Cells, 2019 The gastrointestinal tract harbours the largest population of mast cells in the body; this highly specialised leukocyte cell type is able to adapt its phenotype and function to the microenvironment in which it resides.
Mercé Albert-Bayo +7 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
A theoretical investigation of ferromagnetic tunnel junctions with 4-valued conductances
, 2003 In considering a novel function in ferromagnetic tunnel junctions consisting of ferromagnet(FM)/barrier/FM junctions, we theoretically investigate multiple valued (or multi-level) cell property, which is in principle realized by sensing conductances of ...
Filip A T +27 more
core +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Lactobacillus Re-Engineers Gut Microbiota to Overcome E. coli Colonization Resistance in Mice
Veterinary SciencesThe intestinal health and functionality of animals play pivotal roles in nutrient digestion and absorption, as well as in maintaining defense against pathogenic invasions.
Jianlei Jia +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Research on High-Precision Control of Hydraulic Excavator Based on Optimal Trajectory Planning
IEEE AccessIn this article, the trajectory planning and high-precision motion control of an excavator based on the independent hydraulic system of the load port are studied.
Junxiang Chen +4 more
doaj +1 more source