Results 61 to 70 of about 2,302,006 (298)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Membrane fouling in vacuum membrane distillation for ionic liquid recycling: Interaction energy analysis with the XDLVO approach

, 2018
Membrane fouling, essentially originated from the interactions between foulant and membrane surface, is a big obstacle to use membrane distillation (MD) for ionic liquid recycling from its aqueous solution.
Huanhuan Wu, Wu, Huanhuan, Wang, Junfeng, Wan, Yinhua, Shen, Fei, Fei Shen, Yinhua Wan, Junfeng Wang   +7 more
core   +1 more source

Periosteal Distraction Osteogenesis and Barrier Membrane Application: An Experimental Study in the Rat Calvaria [PDF]

, 2012
Background: Distraction of the periosteum results in the formation of new bone in the gap between the periosteum and the original bone. We postulate that the use of a barrier membrane would be beneficial for new bone formation in periosteal distraction.
Iizuka, Tateyuki, Hideya Haeniwa, Daniel Buser, Pascal Jaun, Tateyuki Iizuka, Saulacic, Nikola, Nikola Saulacic, Benoit Schaller, Jaun, Pascal, Buser, Daniel, Schaller, Benoit, Bosshardt, Dieter, Haeniwa, Hideya, Dieter D. Bosshardt   +13 more
core   +1 more source

Fabrication and Characterization of Semi-Resorbable Bioactive Membrane Derived from Silk Fiber Sheet for Guided Bone Regeneration

Biomimetics
The barrier membrane is a key component in guided bone regeneration (GBR); however, there is no current commercially available membrane universally suitable for all clinical situations.
Kanokporn Santavalimp, Jirut Meesane, Juthakarn Thonglam, Kawintip Prasongyuenyong, Prisana Pripatnanont   +4 more
doaj   +1 more source

Mistura de proteínas morfogenéticas ósseas, hidroxiapatita, osso inorgânico e colágeno envolta por membrana de pericárdio no preenchimento de defeito ósseo segmentar em coelhos Mixture of bone morphogenetic protein, hydroxyapatite, inorganic bone and collagen interposed by pericardium barrier membrane in the filling of the segmental bone defect in rabbits

Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2006
Avaliou-se o uso de biomaterial de origem bovina na regeneração de defeitos ósseos segmentares empregando-se 12 coelhos, fêmeas, da raça Norfolk, com idade de seis meses e pesos entre 3 e 4,5kg.
R.B. Ciani, S.C. Rahal, R.S. Volpi, R. Taga, J.M. Granjeiro, T.M. Cestari, M.J. Mamprim   +6 more
doaj   +1 more source

Basement membrane: Putting up the barriers [PDF]

Current Biology, 1999
The basement membrane is a highly organized extracellular matrix with adhesive and barrier functions. Assembly of this matrix uses two types of cell surface receptor, integrins and dystroglycan, to coordinate formation of a polygonal network of laminin, a major basement membrane protein.
openaire   +2 more sources

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Engineering a superwetting thin film nanofibrous composite membrane with excellent antifouling and self-cleaning properties to separate surfactant-stabilized oil-in-water emulsions

, 2019
In recent years, novel superwetting membranes have gained popularity for oily wastewater treatments via synergy between surface chemistry and topography.
Tian, Miao, Wang, Rong, Liao, Yuan
core   +1 more source

Component network meta-analysis of scaffold materials, platelet-rich fibrin and barrier membranes for alveolar ridge preservation

Frontiers in Oral Health
BackgroundAlveolar ridge preservation (ARP) involves the use of multiple treatment components, including scaffold materials, platelet-rich fibrin (PRF) adjuncts, and barrier membranes.
Jian Zhang, Jie Zhong, Shihan Huang, Ling Zhang   +3 more
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source