Results 51 to 60 of about 2,302,006 (298)

Fast-curing resilin bioshield with tailored stiffness and bioactivity for guided bone regeneration

Nano Research
Severe bone defects pose a formidable clinical challenge in orthopedics, urgently demanding the development of advanced biomaterials to restore structural and functional integrity.
Yusai Zhou, Yajuan Xie, Yunfan Zhang, Xiaomo Liu, Bo Li, Bing Han, Ruichu Zhang, Chaonan Jin, Yao Sun, Chao Ma, Shengxue Yang, Li Miao, Hongjie Zhang, Kai Liu, Yan Wei   +14 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Attrition-resistant membranes for fluidized-bed membrane reactors: Double-skin membranes: Double-skin membranes [PDF]

, 2018
Pd-Ag supported membranes have been prepared by coating a ceramic interdiffusion barrier onto a Hastelloy X (0.2 µm media grade) porous support followed by deposition of the hydrogen selective Pd-Ag (4–5 µm) layer by electroless plating.
Jose Antonio Medrano, Martin van Sint Annaland, Medrano, J.A., Medrano, Jose Antonio, Melendez, Jon, Melendez, J., Jon Melendez, Pacheco Tanaka, D. Alfredo, Gallucci, Fausto, van Sint Annaland, Martin, Pacheco Tanaka, D.A., Alba Arratibel, van Sint Annaland, M., Gallucci, F.; id_orcid, Arratibel, Alba, Fausto Gallucci, Arratibel Plazaola, A., D. Alfredo Pacheco Tanaka   +17 more
core   +1 more source

Advances in research on labyrinth membranous barriers

Journal of Otology, 2015
Integrity of the membranous labyrinth barrier system is of critical importance, which promotes inner ear homeostasis and maintains its features. The membranous labyrinth barrier system is divided into several subsets of barriers which, although independent from each other, are interrelated.
Sun, Wenfang, Wang, Wuqing
openaire   +2 more sources

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Degradable Pure Magnesium Used as a Barrier Film for Oral Bone Regeneration

Journal of Functional Biomaterials, 2022
The barrier membrane plays an extremely critical role in guided bone regeneration (GBR), which determines the success or failure of GBR technology. In order to obtain barrier membranes with high mechanical strength and degradability, some researchers ...
Xianfeng Shan, Yu Xu, Sharafadeen Kunle Kolawole, Ling Wen, Zhenwei Qi, Weiwei Xu, Junxiu Chen   +6 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Rho and Rab Family Small GTPases in the Regulation of Membrane Polarity in Epithelial Cells

Frontiers in Cell and Developmental Biology, 2022
Membrane polarity, defined as the asymmetric distribution of lipids and proteins in the plasma membrane, is a critical prerequisite for the development of multicellular tissues, such as epithelia and endothelia.
Klaus Ebnet, Klaus Ebnet, Klaus Ebnet, Volker Gerke, Volker Gerke, Volker Gerke   +5 more
doaj   +1 more source