Results 71 to 80 of about 6,187,894 (279)

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Factors influencing the solubilization of membrane proteins from Escherichia coli membranes by styrene–maleic acid copolymers [PDF]

, 2020
Styrene–maleic acid (SMA) copolymers are a promising alternative to detergents for the solubilization of membrane proteins. Here we employ Escherichia coli membranes containing KcsA as a model protein to investigate the influence of different ...
Dörr, Jonas M., Sub Membrane Biochemistry & Biophysics, Membrane Biochemistry and Biophysics, Koorengevel, Martijn C., Jahn, Helene, Killian, J. Antoinette, Antoniciello, Federico, Kopf, Adrian H.   +7 more
core   +1 more source

Molecular Dynamics Study on the Reverse Osmosis Using Multilayer Porous Graphene Membranes

Nanomaterials, 2018
In this study, the reverse osmosis (RO) of a salt solution was investigated using a molecular dynamics method to explore the performance of a multilayer porous graphene membrane.
Zhongqiang Zhang, Fujian Zhang, Zhen Liu, Guanggui Cheng, Xiaodong Wang, Jianning Ding   +5 more
doaj   +1 more source

The role of angiogenesis in implant dentistry part II: The effect of bone-grafting and barrier membrane materials on angiogenesis

Medicina Oral, 2016
Background In implant dentistry, bone substitute materials and barrier membranes are used in different treatments including guided bone regeneration (GBR), socket preservation, alveolar ridge augmentation, maxillary sinus elevation, and filling bony ...
M. Saghiri, A. Asatourian, F. García-Godoy, N. Sheibani   +3 more
semanticscholar   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Compilation of information on the interaction of reef sharks with the reef line fishery in the Great Barrier Reef Marine Park: final report to the Great Barrier Reef Marine Park Authority [PDF]

, 2008
[Extract] Three data sets were examined to define the level of interaction of reef associated sharks with the commercial Coral Reef Fin Fish Fishery (CRFFF) within the Great Barrier Reef. Data were examined from; 1) fishery logbooks from 1989-2006; 2) an
Welch, D.J., Ballagh, A., Simpfendorfer, C.A., Mapstone, B.D., Heupel, M.R., Williams, A.J.   +5 more
core   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Understanding membrane pore-wetting in the membrane distillation of oil emulsions via molecular dynamics simulations

, 2018
The escalating volume of oily wastewater, particularly produced water, necessitates efficient means of treatment for the recovery of both the water and oil constituents. Towards this end, membrane distillation (MD) is a promising candidate. Unfortunately,
Le Han, Velioğlu, Sadiye, Sadiye Velioğlu, Han, Le, Jia Wei Chew, Chew, Jia Wei   +5 more
core   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source