Results 101 to 110 of about 3,618,266 (313)

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

open access: yesFEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Mitochondrial targeted prodrug nanoparticles for chemo-photodynamic combinational tumour therapy

open access: yesSmart Materials in Medicine
Prodrug nanoparticles have been explored as an effective means for drug delivery because of controlled drug release in a stimulus-responsive manner. Organellar-targeted drug delivery could enhance the efficacy of cancer therapy. Herein, pH and light dual
Rong Xu   +4 more
doaj   +1 more source

Localized Beams and Dielectric Barriers

open access: yes, 2008
Recalling the similarities between the Maxwell equations for a transverse electric wave in a stratified medium and the quantum mechanical Schroedinger equation in a piece-wise potential, we investigate the analog of the so called particle limit in ...
De Leo, Stefano, Rotelli, Pietro
core  

Families and work: revisiting barriers to employment [PDF]

open access: yes, 2011
"In recent years, considerable effort has been put into supporting parents to make the transition into work. This study was commissioned by the Department for Work and Pensions (DWP) to explore whether these incentives were helping parents to overcome ...
Bashir, Nadia   +4 more
core  

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

open access: yesFEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc   +8 more
wiley   +1 more source

Intratympanic dexamethasone microcrystal-loaded porous PLGA microspheres containing lipoic acid for combined delivery to the inner ear

open access: yesJournal of Otology
Objective To develop a sustained-release codelivery system for intratympanic administration of dexamethasone (DEX) and lipoic acid (LA). Methods DEX microcrystals (MCs) were prepared via precipitation, while LA-loaded porous PLGA microspheres (LPMPs ...
Peili Zhang   +7 more
doaj   +1 more source

Social and economic barriers to adherence among patients at Livingstone General Hospital in Zambia

open access: yesAfrican Journal of Primary Health Care & Family Medicine, 2019
Background: Zambia is one of the countries hardest hit by the human immunodeficiency virus (HIV) and acquired immune deficiency syndrome (AIDS) pandemic with a national HIV prevalence estimated at 14% among those aged 15–49 years in 2012.
Kaala Moomba, Brian van Wyk
doaj   +1 more source

Energy barriers for diffusion on stepped Rh(111) surfaces

open access: yes, 1999
Energy barriers for different moves of a single Rh adatom in the vicinity of steps on Rh(111) surface are studied with molecular statics. Interatomic interactions are modeled by the semi-empirical many-body Rosato-Guillope-Legrand potential. We calculate
Kotrla, M., Maca, F., Trushin, O. S.
core   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

open access: yesFEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

open access: yesFEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi   +7 more
wiley   +1 more source

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