Results 11 to 20 of about 3,935,589 (363)

Validation and stability analysis of a modified lactate dehydrogenase (LDH) test method to be employed for an in vitro viable skin model

open access: yesHeliyon, 2019
In view of increasing numbers of dermatological disorders, transdermal drug delivery along with in vitro research is becoming increasingly popular. Herefore, qualified in vitro skin models are required.
I. Bauhammer, M. Sacha, E. Haltner
doaj   +1 more source

The Question of Analyzing System Safety with Consideration to Human Factor [PDF]

open access: yesInternational Journal of Mathematical, Engineering and Management Sciences, 2021
This article presents the research results of the human factor effect on system safety. The authors used historical data on inductive reasoning to obtain the results. The article shows that there is no good reason to believe that there is no human factor
Iosif Z. Aronov   +2 more
doaj   +1 more source

Alzheimer’s Disease and Age-Related Changes in the Cu Isotopic Composition of Blood Plasma and Brain Tissues of the APPNL-G-F Murine Model Revealed by Multi-Collector ICP-Mass Spectrometry

open access: yesBiology, 2023
Alzheimer’s’ disease (AD) is characterized by the formation of β-amyloid (Aβ) plaques and neurofibrillary tangles of tau protein in the brain. Aβ plaques are formed by the cleavage of the β-amyloid precursor protein (APP).
Kasper Hobin   +4 more
doaj   +1 more source

Retromer-Mediated Trafficking of Transmembrane Receptors and Transporters

open access: yesMembranes, 2015
Transport between the endoplasmatic reticulum, the Golgi-network, the endo-lysosomal system and the cell surface can be categorized as anterograde or retrograde, describing traffic that goes forward or backward, respectively.
Stine C. Klinger   +2 more
doaj   +1 more source

The Effects of Powered Exoskeleton Gait Training on Cardiovascular Function and Gait Performance: A Systematic Review

open access: yesSensors, 2021
Patients with neurological impairments often experience physical deconditioning, resulting in reduced fitness and health. Powered exoskeleton training may be a successful method to combat physical deconditioning and its comorbidities, providing patients ...
Damien Duddy   +5 more
doaj   +1 more source

Effects of fasudil on blood–brain barrier integrity

open access: yesFluids and Barriers of the CNS, 2022
Background Cerebral infarction accounts for 85% of all stroke cases. Even in an era of rapid and effective recanalization using an intravascular approach, the majority of patients have poor functional outcomes.
Kei Sato   +12 more
doaj   +1 more source

Cerebrospinal fluid dynamics and intracranial pressure elevation in neurological diseases

open access: yesFluids and Barriers of the CNS, 2019
The fine balance between the secretion, composition, volume and turnover of cerebrospinal fluid (CSF) is strictly regulated. However, during certain neurological diseases, this balance can be disrupted.
Steven William Bothwell   +2 more
doaj   +1 more source

Methodological and analytical considerations for intra-operative microdialysis

open access: yesFluids and Barriers of the CNS, 2023
Background Microdialysis is a technique that can be utilized to sample the interstitial fluid of the central nervous system (CNS), including in primary malignant brain tumors known as gliomas.
Cecile Riviere-Cazaux   +12 more
doaj   +1 more source

Epidermal Barriers [PDF]

open access: yesCold Spring Harbor Perspectives in Medicine, 2014
The epidermis functions as a physical barrier to the external environment and works to prevent loss of water from the skin. Numerous factors have been implicated in the formation of epidermal barriers, such as cornified envelopes, corneocytes, lipids, junctional proteins, proteases, protease inhibitors, antimicrobial peptides, and transcription factors.
openaire   +2 more sources

Natural Barriers and Policy Barriers [PDF]

open access: yesSSRN Electronic Journal, 2020
This paper investigates whether "natural" trade barriers of a country due to geography and other factors outside the country's control stimulate more or less policy barriers such as tariffs. Our theory predicts that the politician's relative weight on private benefits over social welfare in a "protection-for-sale" setup depends on these "natural ...
Yang Jiao, Shang-Jin Wei
openaire   +2 more sources

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