Results 81 to 90 of about 39,984 (208)

Environmental Effects On Drosophila Brain Development And Learning [PDF]

, 2017
Brain development and behavior are sensitive to a variety of environmental influences including social interactions and physicochemical stressors. Sensory input in situ is a mosaic of both enrichment and stress, yet little is known about how multiple ...
Amei, Amei, De Belle, J. Steven, Roberts, Stephen P., Wang, Xia   +3 more
core   +5 more sources

Dynamic simulation of cardiolipin remodeling: greasing the wheels for an interpretative approach to lipidomics[S]

Journal of Lipid Research, 2010
Cardiolipin is a class of mitochondrial specific phospholipid, which is intricately involved in mitochondrial functionality. Differences in cardiolipin species exist in a variety of tissues and diseases.
Michael A. Kiebish, Rob Bell, Kui Yang, Toan Phan, Zhongdan Zhao, William Ames, Thomas N. Seyfried, Richard W. Gross, Jeffrey H. Chuang, Xianlin Han   +9 more
doaj   +1 more source

Mitochondrial Transplantation as a Therapeutic Strategy for Inherited Mitochondrial Diseases

Advanced Science, Volume 13, Issue 11, 23 February 2026.
Mitochondrial transplantation (MTx) offers a promising therapeutic avenue for mitochondrial diseases. This review comprehensively evaluates MTx, differentiating its feasibility for mtDNA‐ and nDNA‐based disorders. It examines its potential for genetic correction, alongside inherent limitations, technical challenges, and crucial ethical considerations ...
Parmeshar Singh, Amir Tahavvori, Cyrus E. Kuschner, Blanca B. Espin, Jacob Kazmi, Sofhia V. Ramos, Tai Yin, Kei Hayashida, Kanako Ito‐Hagiwara, Yusuke Endo, Keitaro Yoshioka, Jun Hagiwara, Avijot Sohi, Alisha Oropallo, Ghania Haddad, Timmy Li, Lance B. Becker, Junhwan Kim   +17 more
wiley   +1 more source

Associations between anxiety, body mass index, and sex hormones in women [PDF]

, 2019
Background: Several studies have shown a positive association between anxiety and obesity, particularly in women. We aimed to study whether sex hormone alterations related to obesity might play a role in this association.
Bae, Y., Ceglarek, U., Engel, C., Enzenbach, C., Glaesmer, H., Hinz, A., Kratzsch, J., Luck, T., Pabst, A., Riedel-Heller, S., Sacher, J., Stanik, J., Stanikova, D., Thiery, J., Wirkner, K.   +14 more
core   +2 more sources

Cardiolipin's Structure, ATP Synthesis & Barth'S Syndrome [PDF]

Biophysical Journal, 2009
Resonance stabilizes two phosphate high energy H-bonds with the free hydroxyl of cardiolipin (CL) rendering a bicyclic conformation, but only in bilayers. Thus it is symmetrical, displaying 2 pK's. The pK2 varies with the length of its fatty acid chains. With 4 C18:0 chains the pK2 is >8.0. Thus the headgroup surface is a buffer at neutral pH. CL is on
openaire   +1 more source

Development and Validation of the Brief Inventory of Treatment Expectations in Chronic Pain (BITEC)

European Journal of Pain, Volume 30, Issue 2, February 2026.
ABSTRACT Background Expectations shape therapeutic outcomes, yet their systematic assessment remains limited in clinical and research settings. To address this gap, we developed and validated the Brief Instrument for the Assessment of Treatment Expectations in Chronic Pain (BITEC) using Item Response Theory. Methods The study comprised four phases. (I)
Wolnei Caumo, Bárbara Regina França, Jaira Ehlers, Stela Maris de Jezus Castro, Rogério Boff Borges, Vania Naomi Hirakata, Graziele Borges Bueno, Iraci LS da Torres, Felipe Fregni   +8 more
wiley   +1 more source

Severity of Depressive Symptoms by Perceived Stress and Gut Microbiota Composition: A Sex‐Stratified Bayesian Approach in a Non‐Clinical Sample

Stress and Health, Volume 42, Issue 1, February 2026.
ABSTRACT Gut dysbiosis, an imbalance in gut microbiota, is increasingly linked to depression through the microbiota‐gut‐brain axis. Stress is an important risk factor for both gut dysbiosis and depression. Despite evidence of altered gut microbiota composition in patients with depression, little is known about how stress and specific gut microbiota ...
Sylvia De Napoli, Tania Moretta, Sebastiano Ravenda, Leonardo Mancabelli, Francesca Turroni, Andrea Sgoifo, Marco Ventura, Luca Carnevali   +7 more
wiley   +1 more source

Task-dependent Modulation of Cortical Excitability and Balance Control in Individuals with Post-concussion Syndrome [PDF]

, 2017
In most cases, symptoms resolve between 7-10 days post-concussion. However, in 10-15% of the concussed population, symptoms can remain unresolved for months to years following the head injury.
Cinelli, Michael E, Mr, Kalmar, Jayne M, Ms., Kaster, Kristen   +2 more
core   +1 more source

The Postural Tachycardia Syndrome (POTS): Pathophysiology, Diagnosis & Management [PDF]

, 2006
Postural tachycardia syndrome (POTS), characterized by orthostatic tachycardia in the absence of orthostatic hypotension, has been the focus of increasing clinical interest over the last 15 years 1. Patients with POTS complain of symptoms of tachycardia,
Raj, Satish R
core   +1 more source

Emerging roles of pyruvate dehydrogenase phosphatase 1: a key player in metabolic health

Frontiers in Physiology
Pyruvate dehydrogenase phosphatase (PDP), a structurally conserved member of the protein phosphatase C family (PP2C) of proteins, is a key regulatory enzyme responsible for reactivation of the mitochondrial gate-keeper, pyruvate dehydrogenase (PDH ...
Vikalp Kumar, Miriam L. Greenberg
doaj   +1 more source