Results 51 to 60 of about 31,542,963 (350)

The evolutionary conserved proteins CEP90, FOPNL, and OFD1 recruit centriolar distal appendage proteins to initiate their assembly.

open access: yesPLoS Biology, 2022
In metazoa, cilia assembly is a cellular process that starts with centriole to basal body maturation, migration to the cell surface, and docking to the plasma membrane.
Pierrick Le Borgne   +13 more
doaj   +1 more source

Centriolar remodeling underlies basal body maturation during ciliogenesis in Caenorhabditis elegans

open access: yeseLife, 2017
The primary cilium is nucleated by the mother centriole-derived basal body (BB) via as yet poorly characterized mechanisms. BBs have been reported to degenerate following ciliogenesis in the C.
I. Nechipurenko   +3 more
semanticscholar   +1 more source

Replication of basal bodies and centrioles

open access: yesCurrent Opinion in Cell Biology, 1992
During the past year, studies on the centrioles and basal bodies of animal and algal cells, and the spindle pole bodies of yeast and other fungi, have added significantly to our knowledge of how these cell organelles form and how they function in initiating microtubule assembly throughout the cell cycle.
Johnson, Karl A., Rosenbaum, Joel L.
openaire   +3 more sources

BASAL BODIES, BUT NOT CENTRIOLES, IN NAEGLERIA [PDF]

open access: yesThe Journal of Cell Biology, 1971
Amebae of Naegleria gruberi transform into flagellates whose basal bodies have the typical centriole-like structure. The amebae appear to lack any homologous structure, even during mitosis. Basal bodies are constructed during transformation and, in cells transforming synchronously at 25°C, they are first seen about 10 min before flagella are seen.
Chandler Fulton, Allan D. Dingle
openaire   +3 more sources

Repression of GW/P body components and the RNAi microprocessor impacts primary ciliogenesis in human astrocytes

open access: yesBMC Cell Biology, 2011
Background In most cells, the centriolar component of the centrosome can function as a basal body supporting the formation of a primary cilium, a non-motile sensory organelle that monitors information from the extracellular matrix and relays stimuli into
Rattner Jerome B   +2 more
doaj   +1 more source

The management of type 2 diabetes with fixed‐ratio combination insulin degludec/liraglutide (IDegLira) versus basal‐bolus therapy (insulin glargine U100 plus insulin aspart): a short‐term cost‐effectiveness analysis in the UK setting [PDF]

open access: yes, 2018
Aim: To evaluate the cost‐effectiveness of IDegLira versus basal‐bolus therapy (BBT) with insulin glargine U100 plus up to 4 times daily insulin aspart for the management of type 2 diabetes in the UK.
ADVANCE Collaborative Group   +47 more
core   +1 more source

Basal body positioning and anchoring in the multiciliated cell Paramecium tetraurelia: roles of OFD1 and VFL3

open access: yesCilia, 2017
BackgroundThe development of a ciliary axoneme requires the correct docking of the basal body at cytoplasmic vesicles or plasma membrane. In the multiciliated cell Paramecium, three conserved proteins, FOR20, Centrin 2, and Centrin 3 participate in this ...
H. Bengueddach   +3 more
semanticscholar   +1 more source

Cartwheel Architecture of Trichonympha Basal Body

open access: yesScience, 2012
Electron microscopy provides a close-up view of the ninefold-symmetric stacked rings at the base of cilia and flagella.
P. Guichard   +8 more
semanticscholar   +4 more sources

Regulation of cilia abundance in multiciliated cells

open access: yeseLife, 2019
Multiciliated cells (MCC) contain hundreds of motile cilia used to propel fluid over their surface. To template these cilia, each MCC produces between 100-600 centrioles by a process termed centriole amplification.
Rashmi Nanjundappa   +6 more
doaj   +1 more source

Basal body structure and composition in the apicomplexans Toxoplasma and Plasmodium

open access: yesCilia, 2016
The phylum Apicomplexa encompasses numerous important human and animal disease-causing parasites, including the Plasmodium species, and Toxoplasma gondii, causative agents of malaria and toxoplasmosis, respectively.
M. Francia, J. Dubremetz, N. Morrissette
semanticscholar   +1 more source

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