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In metazoa, cilia assembly is a cellular process that starts with centriole to basal body maturation, migration to the cell surface, and docking to the plasma membrane.
Pierrick Le Borgne+13 more
doaj +1 more source
Centriolar remodeling underlies basal body maturation during ciliogenesis in Caenorhabditis elegans
The primary cilium is nucleated by the mother centriole-derived basal body (BB) via as yet poorly characterized mechanisms. BBs have been reported to degenerate following ciliogenesis in the C.
I. Nechipurenko+3 more
semanticscholar +1 more source
Replication of basal bodies and centrioles
During the past year, studies on the centrioles and basal bodies of animal and algal cells, and the spindle pole bodies of yeast and other fungi, have added significantly to our knowledge of how these cell organelles form and how they function in initiating microtubule assembly throughout the cell cycle.
Johnson, Karl A., Rosenbaum, Joel L.
openaire +3 more sources
BASAL BODIES, BUT NOT CENTRIOLES, IN NAEGLERIA [PDF]
Amebae of Naegleria gruberi transform into flagellates whose basal bodies have the typical centriole-like structure. The amebae appear to lack any homologous structure, even during mitosis. Basal bodies are constructed during transformation and, in cells transforming synchronously at 25°C, they are first seen about 10 min before flagella are seen.
Chandler Fulton, Allan D. Dingle
openaire +3 more sources
Background In most cells, the centriolar component of the centrosome can function as a basal body supporting the formation of a primary cilium, a non-motile sensory organelle that monitors information from the extracellular matrix and relays stimuli into
Rattner Jerome B+2 more
doaj +1 more source
The management of type 2 diabetes with fixed‐ratio combination insulin degludec/liraglutide (IDegLira) versus basal‐bolus therapy (insulin glargine U100 plus insulin aspart): a short‐term cost‐effectiveness analysis in the UK setting [PDF]
Aim: To evaluate the cost‐effectiveness of IDegLira versus basal‐bolus therapy (BBT) with insulin glargine U100 plus up to 4 times daily insulin aspart for the management of type 2 diabetes in the UK.
ADVANCE Collaborative Group+47 more
core +1 more source
BackgroundThe development of a ciliary axoneme requires the correct docking of the basal body at cytoplasmic vesicles or plasma membrane. In the multiciliated cell Paramecium, three conserved proteins, FOR20, Centrin 2, and Centrin 3 participate in this ...
H. Bengueddach+3 more
semanticscholar +1 more source
Cartwheel Architecture of Trichonympha Basal Body
Electron microscopy provides a close-up view of the ninefold-symmetric stacked rings at the base of cilia and flagella.
P. Guichard+8 more
semanticscholar +4 more sources
Regulation of cilia abundance in multiciliated cells
Multiciliated cells (MCC) contain hundreds of motile cilia used to propel fluid over their surface. To template these cilia, each MCC produces between 100-600 centrioles by a process termed centriole amplification.
Rashmi Nanjundappa+6 more
doaj +1 more source
Basal body structure and composition in the apicomplexans Toxoplasma and Plasmodium
The phylum Apicomplexa encompasses numerous important human and animal disease-causing parasites, including the Plasmodium species, and Toxoplasma gondii, causative agents of malaria and toxoplasmosis, respectively.
M. Francia, J. Dubremetz, N. Morrissette
semanticscholar +1 more source