Results 211 to 220 of about 87,758 (253)

Cholinergic differentiation in neurogenic basal forebrain cultures

Journal of Neurobiology, 1992
AbstractTo study early events in the central nervous system (CNS) cholinergic development, cells from rat basal fore brain tissue were placed in culture at an age when neurogenesis in vivo is still active [embryonic day (E) 15]. The rapid mortality of these cells in defined medium, with 50% mortality after 5–10 h, was blocked completely by soluble ...
M, Martinic, M P, Lambert, S, Hua, W L, Klein   +3 more
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Basal forebrain knife cuts and medial forebrain bundle self-stimulation

Brain Research, 1988
Current autoradiographic and electrophysiological data suggest that fibers coursing from the diagonal band/medial septum and lateral preoptic area through the medial forebrain bundle (MFB) to the midbrain may carry the reward signals generated by lateral hypothalamic stimulation.
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Sleep-wake mechanisms and basal forebrain circuitry

Frontiers in Bioscience, 2003
The seminal studies by von Economo in humans (1) and by Nauta (2) in rats implicated specific basal forebrain areas at the preoptic level as important in sleep regulation. In the last two decades, studies employing recording of single neurons and monitoring of sleep parameters with subsequent chemical and electron microscopic identification of the ...
Laszlo, Zaborszky, Alvaro, Duque
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Orexins/hypocretins excite basal forebrain cholinergic neurones

Neuroscience, 2001
The orexins (orexin A and B, also known as hypocretin 1 and 2) are two recently identified neuropeptides (de Lecea et al., 1998; Sakurai et al., 1998) which are importantly implicated in the control of wakefulness (for reviews see Hungs and Mignot, 2001; van den Pol, 2000; Willie et al., 2001 ).
Eggermann, Emmanuel, Serafin, Mauro, Bayer, Laurence, Machard, D., Saint-Mleux, B., Jones, B. E., Muhlethaler, Michel   +6 more
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AMNESIA FOLLOWING A DISCRETE BASAL FOREBRAIN LESION

Brain, 1992
Destructive lesions of the basal forebrain are associated with memory impairment in both humans and experimental animals. The basal forebrain is thought to contribute to memory function by providing cholinergic innervation to critical memory structures such as the hippocampus and amygdala.
M K, Morris, D, Bowers, A, Chatterjee, K M, Heilman   +3 more
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Basal forebrain amnesia [PDF]

Neurocase, 2000
Borsutzky, Sabine, Brand, Matthias, Fujiwara, Esther   +2 more
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Basal Forebrain, Memory and Attention

1991
A functional analysis of the basal forebrain (BF), which includes the medial septal area (MSA) and nucleus basalis magnocellularis (NBM), benefits from consideration of its anatomical and neurochemical characteristics. Anatomically, the MSA projects to the hippocampus (H) and the NBM projects to the frontal cortex (FC) (Wenk et al., 1980; Fibiger, 1982)
David S. Olton, Gary L. Wenk, Alicja M. Markowska   +2 more
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Basal Forebrain Cholinergic System: A Functional Analysis

1991
This chapter has been organized empirically, focusing on the types of approaches that have been taken to understand BFCS function. This approach reflects the state of our knowledge about the behavioral and psychological functions of the BFCS. Considerable information has been gathered in the very short time that the BFCS has been the object of intense ...
D, Olton, A, Markowska, M L, Voytko, B, Givens, L, Gorman, G, Wenk   +5 more
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Pharmacology of Basal Forebrain Involvement in Reinforcement

1991
The search for the substrates of reinforcement within the organism began shortly after the initial demonstration that electrical stimulation of discrete brain regions could serve as a reinforcer (Olds and Milner, 1954). This intracranial electrical self-stimulation (ICSS) was assumed to result in the activation of the same neuronal pathways responsible
S I, Dworkin, L J, Porrino, J E, Smith
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Basal forebrain in the context of schizophrenia

Brain Research Reviews, 2000
The human basal forebrain has been notoriously difficult to analyze, and it was only in the last part of the twentieth Century that its various components came into sharper focus. It has now been demonstrated that the main parts of what was previously referred to as the 'substantia innominata' (a neurological equivalent of the geographer's 'terra ...
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