Results 191 to 200 of about 526,321 (280)

Longitudinal associations of rapid eye movement (REM) sleep and slow‐wave sleep with plasma Alzheimer's disease biomarkers

Alzheimer's &Dementia, Volume 22, Issue 10, October 2026.
Abstract INTRODUCTION Data on how sleep architecture relates to progression of plasma Alzheimer's disease biomarkers remains limited. METHODS Sixty‐four cognitively unimpaired older adults (ages 55–90) underwent plasma collection twice 2.6 years apart and polysomnography proximate to the first plasma collection.
Jeongyeon Hwang, Luisa F. Figueredo, Daphne I. Valencia, Thomas M. Tolbert, Eriko Hamada, Li Zhou, Joshua L. Gills, Joaquin Ruiz, Katarina R. Martillo, Sarah S. Chu, Ankita Kumar, Esther M. Blessing, Omonigho M. Bubu, Ankit Parekh, Korey Kam, Anna E. Mullins, David M. Rapoport, Indu Ayappa, Ricardo S. Osorio, Andrew W. Varga   +19 more
wiley   +1 more source

Basal Forebrain Volume and Concurrent Hallucinations and Mild Cognitive Impairment in Parkinson's Disease. [PDF]

Mov Disord Clin Pract
Adamo SM, Mutreja V, Statucka M, Kaya B, Schmitz TW, Ruocco AC, Cohn M.   +6 more
europepmc   +1 more source

Endothermy, neuron counts, and other issues: Further remarks on neurocognitive evolution in fossil vertebrates

The Anatomical Record, Volume 309, Issue 10, Page 2560-2573, October 2026.
Abstract Last year, we challenged the view that large‐bodied theropod dinosaurs such as Tyrannosaurus rex resembled primates in cognition and behavior, a proposition made by Herculano‐Houzel in 2023. More recently, Jensen et al. have criticized our work on this topic, raising methodological and conceptual issues.
Kai R. Caspar, Cristián Gutiérrez‐Ibáñez, Hady George, Thomas R. Holtz Jr., Darren Naish, Grant R. Hurlburt   +5 more
wiley   +1 more source

Mesial temporal tau pathology impacts basal forebrain degeneration in early Alzheimer's disease. [PDF]

Alzheimers Dement
Xia Y, Dean MW, Bourgeat P, Krishnadas N, Maruff P, Masters CL, Villemagne VL, Fripp J, Rowe CC, Doré V, Coulson EJ.   +10 more
europepmc   +1 more source

The Role of Noncoding RNA in MGMT‐Positive Glioblastoma: A Narrative Review

Cancer Medicine, Volume 15, Issue 10, October 2026.
ABSTRACT Glioblastoma (GBM) is the most aggressive primary malignant tumor of the central nervous system and is characterized by rapid progression, frequent recurrence, and poor survival outcomes. The current standard of care, comprising maximal safe surgical resection followed by radiotherapy with concomitant and adjuvant temozolomide (TMZ), has ...
Junfeng Zhao, Jiaxuan Chen, Yingrui Bai, Ying Li, Yiming Han, Chuankun Han, Yintao Li   +6 more
wiley   +1 more source

In Vitro Antioxidant, Antibacterial, and Cholinesterase‐Inhibitory Properties of an Aqueous Euphorbia macroclada Root Extract Obtained by Ultrasound‐Assisted Extraction

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
The aqueous root extract of Euphorbia macroclada was obtained using ultrasound‐assisted extraction (UAE). The extract showed remarkable butyrylcholinesterase (BChE) inhibition relevant to Alzheimer's disease. Strong antioxidant capacity was demonstrated through multiple radical scavenging and reducing assays.
Abdulkadir Gül, Fırat Yılmaz, Fevzi Topal, İnanç Özgen, Ercan Aydoğmuş, Hasan Arslanoğlu   +5 more
wiley   +1 more source

Development of Thalamo‐Telencephalic Circuits in a Reptile

Journal of Comparative Neurology, Volume 534, Issue 10, October 2026.
The development of forebrain connections was investigated in the Alligator. Four circuits were identified: ipsilateral basal nuclei to the dorsal thalamus, ipsilateral lateral forebrain bundle, and ipsilateral and contralateral medial forebrain bundle.
Michael B. Pritz
wiley   +1 more source

Modulation of Endoplasmic Reticulum Stress via CEBPB: A Potential Molecular Link to Therapeutic Action in Substance Use Disorders

CNS Neuroscience &Therapeutics, Volume 32, Issue 10, October 2026.
We identified endoplasmic reticulum (ER) stress modulation as a convergent transcription signature across fentanyl and multiple substance use disorder (SUD)‐relevant treatments. Key ER stress genes, including TRIB3, XBP1, and DDIT3, were downregulated, while CEBPB emerged as a shared upstream regulator linked to ER stress–related proteins.
Cheng Zhang, Hu Li, Ming‐Fen Ho
wiley   +1 more source

Basal Forebrain Volume Predicts Disease Conversion in Prodromal Synucleinopathy. [PDF]

Mov Disord Clin Pract
Churchill L, Konuri A, Ignatavicius A, Anderson J, Lewis SJG, Matar E.   +5 more
europepmc   +1 more source