Results 91 to 100 of about 27,335,908 (329)
American Journal of Psychiatry, 2016 OBJECTIVE Animal models suggest that the development of psychosis involves hyperactivity in the hippocampus that drives increased activity in the midbrain and basal ganglia.
P. Allen +8 more
semanticscholar +1 more source
Advanced Healthcare Materials, EarlyView.The covalent binding of dexamethasone to the surface of polyimide represents the electrically inert part of implantable intraneural devices. This ensures a sustained release of the drug for 9 weeks. In vitro and in vivo tests confirm the reduction of the foreign body reactions and the improved biocompatibility of dexamethasone functionalized polyimide.
Giulia Turrin +19 more
wiley +1 more source
Transcriptome analysis in a rat model of l-DOPA-induced dyskinesia
Neurobiology of Disease, 2004 We have examined the pattern of striatal messenger RNA expression of over 8000 genes in a rat model of levodopa (l-DOPA)-induced dyskinesia and Parkinson disease (PD).
Christine Konradi +7 more
doaj
The Basal Ganglia and Motor Control
Neural Plasticity, 2003 This paper briefly reviews the functional anatomy of the basal ganglia and their relationships with the thalamocortical system. The basal ganglia, including the striatum, pallidum, subthalamic nucleus, and substantia nigra, are involved in a number of ...
Henk J. Groenewegen
doaj +1 more source
Advanced Healthcare Materials, EarlyView.A new oxaliplatin‐based Pt(IV) prodrug bearing a Mn(II) superoxide dismutase mimic is synthesized and studied, in vitro and in vivo, in the context of colorectal cancer. Encapsulation of this prodrug in an easy‐to‐implement PEGylated micelle formulation demonstrated the highest in vivo anticancer activity among all the tested conditions, supporting the
Alvaro Lopez‐Sanchez +14 more
wiley +1 more source
Neurobiology of Disease, 2011 6-Hydroxydopamine (6-OHDA) lesions are being used in the mouse for basic research on Parkinson's disease and L-DOPA-induced dyskinesia. We set out to compare unilateral lesion models produced by intrastriatal or intramesencephalic injections of a fixed 6-
Veronica Francardo +5 more
doaj
Obsessive Compulsive Disorder in a Woman with Left Basal Ganglia Infarct: A Case Report
Behavioural Neurology, 1997 This report presents a syndrome resembling obsessive convulsive disorder (OCD) secondary to a stroke in the left basal ganglia. The patient's syndrome is virtually identical to those that have been described in bilateral damage of the basal ganglia ...
Faustino Lopez-Rodriguez +2 more
doaj +1 more source
A Sing-Song Way of Vocalizing: Generalization and Specificity in Language and Birdsong. [PDF]
, 2017 Spoken languages such as German are extremely discrete, whereas others such as Portuguese are melodic or "sing-song" wherein identifying a word relies on what comes before and after.
Farias-Virgens, Madza +1 more
core +1 more source
Pathogenesis of dystonia: is it of cerebellar or basal ganglia origin?
Journal of Neurology Neurosurgery & Psychiatry, 2017 Dystonia is a disorder of motor programmes controlling semiautomatic movements or postures, with clinical features such as sensory trick, which suggests sensorimotor mismatch as the basis. Dystonia was originally classified as a basal ganglia disease. It
R. Kaji, K. Bhatia, A. Graybiel
semanticscholar +1 more source
Advanced Materials, EarlyView.Convergence drawing is used to create flexible, microscale, multifunctional fiber‐based neural probes. Optimized materials selection enables individual devices to perform neural recording, electrical stimulation, optogenetics, fiber photometry, fluid delivery, and voltammetric neurotransmitter detection in rodents.
Nicolette Driscoll +16 more
wiley +1 more source