Results 11 to 20 of about 246,657 (284)
Rodent models of impulsive–compulsive behaviors in Parkinson's disease: How far have we reached?
Neurobiology of Disease, 2015 There is increasing awareness that the medications used to treat the motor symptoms of Parkinson's disease (PD) contribute to the development of behavioral addictions, which have been clinically defined as impulsive–compulsive behaviors (ICBs).
M. Angela Cenci +3 more
doaj +1 more source
Nondirected axonal growth on basal lamina from avian embryonic neural retina [PDF]
, 1987 The vitreous surface of the embryonic avian retinal neuroepithelium was isolated by mechanical disruption of the retina mounted between 2 adhesive substrata.
Halfter, W. +2 more
core +1 more source
Neurobiology of Disease, 2017 Striatal neurons forming the indirect pathway (iSPNs) are particularly vulnerable in Huntington's disease (HD). In this study we set out to investigate morphological and physiological alterations of iSPNs in two mouse models of HD with relatively slow ...
Irene Sebastianutto +2 more
doaj +1 more source
Saccade learning with concurrent cortical and subcortical basal ganglia loops [PDF]
, 2013 The Basal Ganglia is a central structure involved in multiple cortical and subcortical loops. Some of these loops are believed to be responsible for saccade target selection.
Girard, Benoît +2 more
core +3 more sources
Involvement of the cortico-basal ganglia-thalamocortical loop in developmental stuttering [PDF]
, 2019 Stuttering is a complex neurodevelopmental disorder that has to date eluded a clear explication of its pathophysiological bases. In this review, we utilize the Directions Into Velocities of Articulators (DIVA) neurocomputational modeling framework to ...
Chang, Soo-Eun, Guenther, Frank H.
core +1 more source
Neurobiology of Disease, 2016 Mice with striatal 6-hydroxydopamine (6-OHDA) lesions are widely used as a model to study the effects of neurorestorative, symptomatic, or antidyskinetic treatments for Parkinson's disease (PD).
Francesco Bez +2 more
doaj +1 more source
Integration of navigation and action selection functionalities in a computational model of cortico-basal ganglia-thalamo-cortical loops [PDF]
, 2005 This article describes a biomimetic control architecture affording an animat both action selection and navigation functionalities. It satisfies the survival constraint of an artificial metabolism and supports several complementary navigation strategies ...
Berthoz, Alain +4 more
core +3 more sources
Neurobiology of Disease, 2016 Rodent models of l-DOPA-induced dyskinesia (LID) are essential to investigate pathophysiological mechanisms and treatment options. Ratings of abnormal involuntary movements (AIMs) are used to capture both qualitative and quantitative features of ...
Irene Sebastianutto +3 more
doaj +1 more source
Transcriptome analysis in a rat model of l-DOPA-induced dyskinesia
Neurobiology of Disease, 2004 We have examined the pattern of striatal messenger RNA expression of over 8000 genes in a rat model of levodopa (l-DOPA)-induced dyskinesia and Parkinson disease (PD).
Christine Konradi +7 more
doaj +1 more source
Neurobiology of Disease, 2011 6-Hydroxydopamine (6-OHDA) lesions are being used in the mouse for basic research on Parkinson's disease and L-DOPA-induced dyskinesia. We set out to compare unilateral lesion models produced by intrastriatal or intramesencephalic injections of a fixed 6-
Veronica Francardo +5 more
doaj +1 more source