Optimized AAV capsids for basal ganglia diseases show robust potency and distribution. [PDF]
Leib DE+13 more
europepmc +1 more source
Objective The growing demand for personalized treatment in multiple sclerosis (MS) highlights the need for more precise biomarkers that can outperform magnetic resonance imaging and clinical assessment in patient stratification. Advances in multiplex proteomic technologies suggest that cerebrospinal fluid (CSF) analysis at MS onset may not only improve
Laura Ghezzi+10 more
wiley +1 more source
Is speech function lateralised in the basal ganglia? Evidence from de novo Parkinson's disease. [PDF]
Rusz J+13 more
europepmc +1 more source
Physical stimulation strategies have emerged as a therapeutic avenue for the regeneration of spiral ganglion neurons. This review explores diverse physical stimulation modalities—including topographical modulation, electrical stimulation, and photostimulation—each operating through distinct mechanisms to regulate SGN biological behavior. By elucidating
Yuhan Bai+7 more
wiley +1 more source
Inhibitory basal ganglia nuclei differentially innervate pedunculopontine nucleus subpopulations and evoke differential motor and valence behaviors. [PDF]
Fallah M+4 more
europepmc +1 more source
Exosomes in Intervertebral Disc Regeneration: Roles, Opportunities, and Challenges
Factors of Intervertebral Disc Degeneration Extracellular Matrix (ECM) Exosomes and Intervertebral Disc Degeneration (IVDD) Exosome‐Mediated Therapy for IVDD of Different Cell Sources Application of Engineered Exosomes in IVDD Clinical Application of Exosomes in IVDD Treatment Conclusion and Future Perspectives. Intervertebral disc degeneration (IVDD),
Xianglong Zhou+7 more
wiley +1 more source
Minimally invasive surgery for bilateral large basal ganglia hemorrhage: a rare case report and insights from literature. [PDF]
Le TCL+4 more
europepmc +1 more source
Predicting ecology and hearing sensitivities in Parapontoporia—An extinct long‐snouted dolphin
Abstract Analyses of the cetacean (whale and dolphin) inner ear provide glimpses into the ecology and evolution of extinct and extant groups. The paleoecology of the long‐snouted odontocete (toothed whale) group, Parapontoporia, is primarily marine with its depositional context also suggesting freshwater tolerance.
Joyce Sanks, Rachel Racicot
wiley +1 more source
A novel TIMM8A mutation in Mohr-Tranebjaerg syndrome without hearing loss and with basal ganglia iron deposition. [PDF]
Ventura I+4 more
europepmc +1 more source