Results 241 to 250 of about 157,060 (309)

Mapping opioid exposure through prescription data and postmortem analysis of opioid drugs in multiple tissues

British Journal of Clinical Pharmacology, EarlyView.
Background and Purpose Although opioids are central to end of life (EoL) care, tissue‐level opioid exposure remains poorly understood. The objective of this study was to characterize the relationship between prescription‐derived morphine equivalent daily dose (MEDD) and measured morphine concentrations across multiple organs.
Niamh Higgins, Alan Wells, Nimish Patel, Nicole Muttera, Mattia Trunfio, Alessandra Manca, Amedeo De Nicolò, Micol Ferrara, Stefano Bonora, Jessica Cusato, Alice Palermiti, Antonio D'Avolio, Marissa Borochoff, Patricia K. Riggs, Elizabeth Hastie, Rabia S. Atayee, Stephanie Solso, Cheryl Dullano, Vanessa Gomez‐Moreno, Tara Tenenbaum, Robert Deiss, Davey M. Smith, Antoine Chaillon, Sara Gianella   +23 more
wiley   +1 more source

Decoding basal ganglia motor circuit dysfunction from handwriting: a physics-informed neural signal interpretation framework for Parkinson's disease screening. [PDF]

Front Neuroinform
Batri K, Lakshmi S, Khan S, Iqbal Z, Alhefdi M, Atteia G, Murugan S.   +6 more
europepmc   +1 more source

Reward-driven adaptation of movements requires strong recurrent basal ganglia-cortical loops. [PDF]

Proc Natl Acad Sci U S A
Leblois A, Boraud T, Hansel D.
europepmc   +1 more source

New opportunities for bioscaffold‐enabled spinal cord injury repair

BMEMat, EarlyView.
Schematic illustration of bioscaffolds for spinal cord injury repair. We summarize the effects of bioscaffold properties on SCI repair, highlight different types of bioscaffolds, various fabrication strategies, and in vivo transformations for the clinical development of SCI‐repairing bioscaffolds.
Xiaoqing Qi, Yicheng Fu, Zhaoliang Su, Li Li, Subrata Chakrabarti, Peng Li, Yilun Wu, Fang Liu, Teng Gao, Zhifeng Dong, Lei Liu, Pei Cao   +11 more
wiley   +1 more source

How the dynamic interplay of cortico-basal ganglia-thalamic pathways shapes the time course of deliberation and commitment. [PDF]

PLoS Comput Biol
Yu Z, Verstynen T, Rubin JE.
europepmc   +1 more source

Basal ganglia

, 2009
Jeremy Jones, Rohit Sharma, Frank Gaillard   +2 more
openaire   +1 more source

Force stimulation promotes nerve regeneration by restoring cellular energy

BMEMat, EarlyView.
Mechanical stimulation can help nerves regenerate in various ways. We developed two devices (a piezo‐motor‐driven stretching device and a SAW‐based actuator) to apply mechanical stimulation to sciatic nerve and DRG neurons. Our study shows that appropriate mechanical force stimulation can promote regeneration by restoring the energy supply to the ...
Zhe Wang, Chen Cai, Hetao Xie, Yupeng Yang, Lei Li, Nik Ahmad Nizam Nik Malek, Wan Hairul Anuar Kamaruddin, Meiwan Chen, Yuanhua Sang, Bing Ji, Zenan Wang   +10 more
wiley   +1 more source

Genetic background of neurological disorders with basal ganglia calcification. [PDF]

J Neurol
Yektay Farahmand M, Wallenius J, Wasselius J, Gråhamn O, Puschmann A, Ilinca A.   +5 more
europepmc   +1 more source

Consistent cortico-basal ganglia-cerebellar activation in early motor sequence learning: a systematic review and meta-analysis. [PDF]

Transl Psychiatry
Chen W, Li T, Luo J, Chen J, Lv Y.
europepmc   +1 more source