Results 21 to 30 of about 246,657 (284)

Potential mechanisms for imperfect synchronization in parkinsonian basal ganglia [PDF]

open access: yes, 2012
Neural activity in the brain of parkinsonian patients is characterized by the intermittently synchronized oscillatory dynamics. This imperfect synchronization, observed in the beta frequency band, is believed to be related to the hypokinetic motor ...
Park, Choongseok, Rubchinsky, Leonid
core   +3 more sources

Cerebellum: an explanation for dystonia? [PDF]

open access: yes, 2017
Dystonia is a movement disorder that is characterized by involuntary muscle contractions, abnormal movements and postures, as well as by non-motor symptoms, and is due to abnormalities in different brain areas.
Berardelli, Alfredo, Bologna, Matteo
core   +1 more source

Amphetamine-induced abnormal movements occur independently of both transplant- and host-derived serotonin innervation following neural grafting in a rat model of Parkinson's disease

open access: yesNeurobiology of Disease, 2009
Serotonin has been postulated to play a role in the transplant-induced involuntary movements that occur following intrastriatal grafts of ventral mesencephalic tissue in the treatment of Parkinson's disease.
Emma Louise Lane   +2 more
doaj   +1 more source

Isolation, characterization, and substrate properties of the external limiting membrane from the avian embryonic optic tectum [PDF]

open access: yes, 1990
The external limiting membrane of the avian embryonic optic tectum is isolated by mechanically separating the neuronal mesencephalon from the overlying mesenchymal tissue.
Adler   +58 more
core   +1 more source

Neuroinflammation in the generation of post-transplantation dyskinesia in Parkinson's disease

open access: yesNeurobiology of Disease, 2008
The observation that neural grafts can induce dyskinesias has severely hindered the development of a transplantation therapy for Parkinson's disease (PD).
E.L. Lane   +4 more
doaj   +1 more source

A basal ganglia inspired model of action selection evaluated in a robotic survival task. [PDF]

open access: yes, 2003
The basal ganglia system has been proposed as a possible neural substrate for action selection in the vertebrate brain. We describe a robotic implementation of a model of the basal ganglia and demonstrate the capacity of this system to generate adaptive ...
Cuzin, V.   +4 more
core   +3 more sources

The impact of graft size on the development of dyskinesia following intrastriatal grafting of embryonic dopamine neurons in the rat

open access: yesNeurobiology of Disease, 2006
Intrastriatal transplants of embryonic ventral mesencephalon can cause dyskinesia in patients with Parkinson's disease (PD). We assessed the impact of transplant size on the development of graft-induced dyskinesia.
E.L. Lane   +3 more
doaj   +1 more source

Increased bradykinesia in Parkinson’s disease with increased movement complexity: elbow flexion-extension movements [PDF]

open access: yes, 2008
The present research investigates factors contributing to bradykinesia in the control of simple and complex voluntary limb movement in Parkinson’s disease (PD) patients.
Geelen, J.A.G.   +3 more
core   +4 more sources

Autoimmune basal ganglia encephalitis associated with anti-recoverin antibodies: A case report

open access: yeseNeurologicalSci, 2021
Autoimmune basal ganglia encephalitis causes neurological symptoms such as parkinsonism associated with basal ganglia lesions. Here, we report a case of autoimmune basal ganglia encephalitis without retinal lesions or malignancy harboring anti-recoverin ...
Yuki Kitazaki   +8 more
doaj   +1 more source

Temporal discrimination: Mechanisms and relevance to adult-onset dystonia [PDF]

open access: yes, 2017
Temporal discrimination is the ability to determine that two sequential sensory stimuli are separated in time. For any individual, the temporal discrimination threshold (TDT) is the minimum interval at which paired sequential stimuli are perceived as ...
Beck, Rebecca   +7 more
core   +1 more source

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