Results 21 to 30 of about 28,372,502 (356)

The Ictal Signature of Thalamus and Basal Ganglia in Focal Epilepsy

open access: yesNeurology, 2020
Objective To determine the involvement of subcortical regions in human epilepsy by analyzing direct recordings from these regions during epileptic seizures using stereo-EEG (SEEG).
F. Pizzo   +12 more
semanticscholar   +1 more source

Rodent models of impulsive–compulsive behaviors in Parkinson's disease: How far have we reached?

open access: yesNeurobiology of Disease, 2015
There is increasing awareness that the medications used to treat the motor symptoms of Parkinson's disease (PD) contribute to the development of behavioral addictions, which have been clinically defined as impulsive–compulsive behaviors (ICBs).
M. Angela Cenci   +3 more
doaj   +1 more source

Nondirected axonal growth on basal lamina from avian embryonic neural retina [PDF]

open access: yes, 1987
The vitreous surface of the embryonic avian retinal neuroepithelium was isolated by mechanical disruption of the retina mounted between 2 adhesive substrata.
Halfter, W.   +2 more
core   +1 more source

Alterations of striatal indirect pathway neurons precede motor deficits in two mouse models of Huntington's disease

open access: yesNeurobiology of Disease, 2017
Striatal neurons forming the indirect pathway (iSPNs) are particularly vulnerable in Huntington's disease (HD). In this study we set out to investigate morphological and physiological alterations of iSPNs in two mouse models of HD with relatively slow ...
Irene Sebastianutto   +2 more
doaj   +1 more source

Saccade learning with concurrent cortical and subcortical basal ganglia loops [PDF]

open access: yes, 2013
The Basal Ganglia is a central structure involved in multiple cortical and subcortical loops. Some of these loops are believed to be responsible for saccade target selection.
Girard, Benoît   +2 more
core   +3 more sources

Integration of navigation and action selection functionalities in a computational model of cortico-basal ganglia-thalamo-cortical loops [PDF]

open access: yes, 2005
This article describes a biomimetic control architecture affording an animat both action selection and navigation functionalities. It satisfies the survival constraint of an artificial metabolism and supports several complementary navigation strategies ...
Berthoz, Alain   +4 more
core   +3 more sources

Basal Ganglia Circuits for Action Specification.

open access: yesAnnual Review of Neuroscience, 2020
Behavior is readily classified into patterns of movements with inferred common goals-actions. Goals may be discrete; movements are continuous. Through the careful study of isolated movements in laboratory settings, or via introspection, it has become ...
Junchol Park   +2 more
semanticscholar   +1 more source

Dramatic differences in susceptibility to l-DOPA-induced dyskinesia between mice that are aged before or after a nigrostriatal dopamine lesion

open access: yesNeurobiology of Disease, 2016
Mice with striatal 6-hydroxydopamine (6-OHDA) lesions are widely used as a model to study the effects of neurorestorative, symptomatic, or antidyskinetic treatments for Parkinson's disease (PD).
Francesco Bez   +2 more
doaj   +1 more source

The basal ganglia [PDF]

open access: yesTrends in Neurosciences, 1995
Augood SJ, Penney JB Jr, Friberg IK, Breakefield XO, Young AB, Ozelius LJ, Standaert DG: Expression of the early-onset torsion dystonia gene (DYT1) in human brain.Ann Neurol 1998, 43:669-673.Bejjani BP, Damier P, Arnulf I, Thivard L, Bonnet AM, Dormont D, Cornu P, Pidoux B, Samson Y, Agid Y.
openaire   +3 more sources

Validation of an improved scale for rating l-DOPA-induced dyskinesia in the mouse and effects of specific dopamine receptor antagonists

open access: yesNeurobiology of Disease, 2016
Rodent models of l-DOPA-induced dyskinesia (LID) are essential to investigate pathophysiological mechanisms and treatment options. Ratings of abnormal involuntary movements (AIMs) are used to capture both qualitative and quantitative features of ...
Irene Sebastianutto   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy