Results 31 to 40 of about 117,087 (348)
Temporal discrimination: Mechanisms and relevance to adult-onset dystonia [PDF]
, 2017 Temporal discrimination is the ability to determine that two sequential sensory stimuli are separated in time. For any individual, the temporal discrimination threshold (TDT) is the minimum interval at which paired sequential stimuli are perceived as ...
Beck, Rebecca +7 more
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Bi-allelic JAM2 Variants Lead to Early-Onset Recessive Primary Familial Brain Calcification. [PDF]
, 2020 Primary familial brain calcification (PFBC) is a rare neurodegenerative disorder characterized by a combination of neurological, psychiatric, and cognitive decline associated with calcium deposition on brain imaging. To date, mutations in five genes have
A. Athanasiou-Fragkouli +86 more
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Neurology International, 2018 Chorea is thought to be caused by deactivation of the indirect pathway in the basal ganglia circuit. However, few imaging studies have evaluated the basal ganglia circuit in actual patients with chorea.
Nobuyuki Ishii +5 more
doaj +1 more source
Jules Bernard Luys: from a description of the subthalamic nucleus to hypnotism [PDF]
Arquivos de Neuro-Psiquiatria, 2020 The authors review the role of Jules Bernard Luys in the discovery of the subthalamic nucleus (STN) over 150 years ago. The relationships between the STN and movement disorders, particularly hemiballismus and Parkinson’s disease, are well known.
Alex Tiburtino MEIRA +6 more
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Dystonia: sparse synapses for D2 receptors in striatum of a DYT1 knock-out mouse model [PDF]
, 2020 Dystonia pathophysiology has been partly linked to downregulation and dysfunction of dopamine D2 receptors in striatum. We aimed to investigate the possible morpho-structural correlates of D2 receptor downregulation in the striatum of a DYT1 Tor1a mouse ...
Biagioni, S. +8 more
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Translational Psychiatry, 2022 Obsessive-compulsive disorder (OCD) is a highly disabling mental illness that can be divided into frequent primary and rarer organic secondary forms. Its association with secondary autoimmune triggers was introduced through the discovery of Pediatric ...
Dominique Endres +18 more
doaj +1 more source
Frontiers in Aging Neuroscience, 2023 IntroductionThe cerebellum and basal ganglia were initially considered anatomically distinct regions, each connected via thalamic relays which project to the same cerebral cortical targets, such as the motor cortex. In the last two decades, transneuronal
Vineeth Radhakrishnan +9 more
doaj +1 more source
, 2014 Neurotoxicity refers to the direct or indirect effect of chemicals that disrupt the nervous system of humans or animals. Numerous chemicals can produce neurotoxic diseases in humans, and many more are used as experimental tools to disturb or damage the ...
Brust +15 more
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Involvement of the cortico-basal ganglia-thalamocortical loop in developmental stuttering [PDF]
, 2019 Stuttering is a complex neurodevelopmental disorder that has to date eluded a clear explication of its pathophysiological bases. In this review, we utilize the Directions Into Velocities of Articulators (DIVA) neurocomputational modeling framework to ...
Chang, Soo-Eun, Guenther, Frank H.
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Decline and fall:a biological, developmental, and psycholinguistic account of deliberative language processes and ageing [PDF]
, 2011 Background: This paper reviews the role of deliberative processes in language: those language processes that require central resources, in contrast to the automatic processes of lexicalisation, word retrieval, and parsing.
Harley, Trevor A. +2 more
core +2 more sources