Results 31 to 40 of about 117,260 (330)

Cortical and Striatal Circuits in Huntington's Disease

open access: yes, 2020
Huntington's disease (HD) is a hereditary neurodegenerative disorder that typically manifests in midlife with motor, cognitive, and/or psychiatric symptoms.
Blumenstock, S., Dudanova, I.
core   +1 more source

Basal ganglia‐cortical structural connectivity in Huntington's disease [PDF]

open access: yesHuman Brain Mapping, 2015
AbstractHuntington's disease is an incurable neurodegenerative disease caused by inheritance of an expanded cytosine‐adenine‐guanine (CAG) trinucleotide repeat within the Huntingtin gene. Extensive volume loss and altered diffusion metrics in the basal ganglia, cortex and white matter are seen when patients with Huntington's disease (HD) undergo ...
Novak M.J.U.   +7 more
openaire   +3 more sources

Decline and fall:a biological, developmental, and psycholinguistic account of deliberative language processes and ageing [PDF]

open access: yes, 2011
Background: This paper reviews the role of deliberative processes in language: those language processes that require central resources, in contrast to the automatic processes of lexicalisation, word retrieval, and parsing.
Harley, Trevor A.   +2 more
core   +2 more sources

Brain Magnetic Resonance Imaging Characteristics of Anti-Leucine-Rich Glioma-Inactivated 1 Encephalitis and Their Clinical Relevance: A Single-Center Study in China

open access: yesFrontiers in Neurology, 2021
Objective: To characterize the magnetic resonance imaging (MRI) features of anti-leucine-rich glioma-inactivated 1 (LGI1) encephalitis and explore their clinical relevance.Methods: Patients with anti-LGI1 encephalitis who underwent MRI at our center were
Xiali Shao   +8 more
doaj   +1 more source

The imaging features of perivascular spaces in differentiation of cerebral small vessel disease and multiple sclerosis

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery, 2019
Objective To investigate the imaging features differences of perivascular spaces(PVS) between cerebral small vessel disease(cSVD) and multiple sclerosis(MS).
Xue⁃hong HUANG   +5 more
doaj   +1 more source

Vascular Risk Factors and Diseases Modulate Deficits of Reward-Based Reversal Learning in Acute Basal Ganglia Stroke. [PDF]

open access: yesPLoS ONE, 2016
BACKGROUND:Besides motor function, the basal ganglia have been implicated in feedback learning. In patients with chronic basal ganglia infarcts, deficits in reward-based reversal learning have previously been described.
Ulla K Seidel   +4 more
doaj   +1 more source

Ontogeny of synaptophysin and synaptoporin in the central nervous system [PDF]

open access: yes, 1993
The expression of the synaptic vesicle antigens synaptophysin (SY) and synaptoporin (SO) was studied in the rat striatum, which contains a nearly homogeneous population of GABAergic neurons. In situ hybridization revealed high levels of SY transcripts in
B. Marquèze-Pouey   +36 more
core   +1 more source

Voluntary saccade inhibition deficits correlate with extended white-matter cortico-basal atrophy in Huntington's disease

open access: yesNeuroImage: Clinical, 2017
The ability to inhibit automatic versus voluntary saccade commands in demanding situations can be impaired in neurodegenerative diseases such as Huntington's disease (HD).
Israel Vaca-Palomares   +5 more
doaj   +1 more source

Increased bradykinesia in Parkinson’s disease with increased movement complexity: elbow flexion-extension movements [PDF]

open access: yes, 2008
The present research investigates factors contributing to bradykinesia in the control of simple and complex voluntary limb movement in Parkinson’s disease (PD) patients.
Geelen, J.A.G.   +3 more
core   +4 more sources

Sex Commonalities and Differences in Obesity-Related Alterations in Intrinsic Brain Activity and Connectivity. [PDF]

open access: yes, 2018
OBJECTIVE:This study aimed to characterize obesity-related sex differences in the intrinsic activity and connectivity of the brain's reward networks. METHODS:Eighty-six women (n = 43) and men (n = 43) completed a 10-minute resting functional magnetic ...
Anderberg   +44 more
core   +1 more source

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