Results 41 to 50 of about 117,087 (348)

Cortical and Striatal Circuits in Huntington's Disease

, 2020
Huntington's disease (HD) is a hereditary neurodegenerative disorder that typically manifests in midlife with motor, cognitive, and/or psychiatric symptoms.
Blumenstock, S., Dudanova, I.
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Cerebral activations related to ballistic, stepwise interrupted and gradually modulated movements in parkinson patients [PDF]

, 2012
Patients with Parkinson's disease (PD) experience impaired initiation and inhibition of movements such as difficulty to start/stop walking. At single-joint level this is accompanied by reduced inhibition of antagonist muscle activity.
A Berardelli, A Berardelli, A Berardelli, A Nambu, A Nambu, AC Bostan, AC Kreitzer, AR Aron, AR Crossman, B Draganski, Bauke M. de Jong, Bernard A. Conway, BM de Jong, BM de Jong, C Rorden, Carolien M. Toxopeus, CD Marsden, CM Toxopeus, CM Toxopeus, D Eidelberg, DC Knill, DS Hoffman, E Gowen, ED Playford, EH Yeterian, EH Yeterian, FA Middleton, G Ebersbach, GE Alexander, GE Alexander, GN Lewis, Gopal Valsan, H Boecker, H Raptis, H Yu, HE den Ouden, HJ Groenewegen, J Hore, J Shires, JA Obeso, JC Rothwell, JD Kropotov, JF Kalaska, JM Kemp, JP Coxon, JS Freeman, JW Mink, JW Mink, JW Mink, JW Mink, K Kaneda, KA Josephs, KJ Friston, KJ Worsley, Klaus L. Leenders, LD Selemon, LK Teune, LL Rubchinsky, M Annett, M Beudel, M DeLong, M Jahanshahi, M Jahanshahi, M Jueptner, M Samuel, MH Schieber, MJ Frank, MM Amick, MM Hoehn, MR DeLong, MR DeLong, MS Matell, N Dounskaia, N Giladi, Natasha M. Maurits, NL Cerminara, O Rascol, O Sporns, P Joti, P Praamstra, P Redgrave, Paul L. Gribble, R Benecke, R Romo, RC Miall, RL Albin, RN Lemon, RS Turner, S Donovan, S Fahn, S Gauggel, S Grillner, S Hirano, S Jahfari, S Lehericy, S Luzzi, S Meunier, SE Leh, SP Wise, T Heida, T Ohyama, U Castiello, U Sabatini, VM Zatsiorsky, W Hauber, Y Jiang, Y Ma   +106 more
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Brain Magnetic Resonance Imaging Characteristics of Anti-Leucine-Rich Glioma-Inactivated 1 Encephalitis and Their Clinical Relevance: A Single-Center Study in China

Frontiers in Neurology, 2021
Objective: To characterize the magnetic resonance imaging (MRI) features of anti-leucine-rich glioma-inactivated 1 (LGI1) encephalitis and explore their clinical relevance.Methods: Patients with anti-LGI1 encephalitis who underwent MRI at our center were
Xiali Shao, Xiali Shao, Siyuan Fan, Huan Luo, Ting Yat Wong, Weihong Zhang, Hongzhi Guan, Anqi Qiu, Anqi Qiu   +8 more
doaj   +1 more source

Basal ganglia‐cortical structural connectivity in Huntington's disease [PDF]

Human Brain Mapping, 2015
AbstractHuntington's disease is an incurable neurodegenerative disease caused by inheritance of an expanded cytosine‐adenine‐guanine (CAG) trinucleotide repeat within the Huntingtin gene. Extensive volume loss and altered diffusion metrics in the basal ganglia, cortex and white matter are seen when patients with Huntington's disease (HD) undergo ...
Novak M.J.U., Seunarine K.K., Gibbard C.R., Mccolgan P., Draganski B., Friston K., Clark C.A., Tabrizi S.J.   +7 more
openaire   +3 more sources

The imaging features of perivascular spaces in differentiation of cerebral small vessel disease and multiple sclerosis

Chinese Journal of Contemporary Neurology and Neurosurgery, 2019
Objective To investigate the imaging features differences of perivascular spaces(PVS) between cerebral small vessel disease(cSVD) and multiple sclerosis(MS).
Xue⁃hong HUANG, Xiao⁃dong CHEN, San⁃xin LIU, Si⁃yuan LIAO , Bing⁃jun ZHANG, Zheng⁃qi LU   +5 more
doaj   +1 more source

Vascular Risk Factors and Diseases Modulate Deficits of Reward-Based Reversal Learning in Acute Basal Ganglia Stroke. [PDF]

PLoS ONE, 2016
BACKGROUND:Besides motor function, the basal ganglia have been implicated in feedback learning. In patients with chronic basal ganglia infarcts, deficits in reward-based reversal learning have previously been described.
Ulla K Seidel, Janine Gronewold, Manon Wicking, Christian Bellebaum, Dirk M Hermann   +4 more
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Binary and nonbinary description of hypointensity for search and retrieval of brain MR images [PDF]

, 2009
Diagnosis accuracy in the medical field, is mainly affected by either lack of sufficient understanding of some diseases or the inter/intra-observer variability of the diagnoses.
Cetin, Mujdat, Chen, Xiaojing, Ekin, Ahmet, Ercil, Aytul, Erçil, Aytül, Jasinschi, Radu, Unay, Devrim, van Buchem, Mark A., Çetin, Müjdat, Ünay, Devrim   +9 more
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Voluntary saccade inhibition deficits correlate with extended white-matter cortico-basal atrophy in Huntington's disease

NeuroImage: Clinical, 2017
The ability to inhibit automatic versus voluntary saccade commands in demanding situations can be impaired in neurodegenerative diseases such as Huntington's disease (HD).
Israel Vaca-Palomares, Brian C. Coe, Donald C. Brien, Aurelio Campos-Romo, Douglas P. Munoz, Juan Fernandez-Ruiz   +5 more
doaj   +1 more source

Regional Distributions of Iron, Copper and Zinc and Their Relationships With Glia in a Normal Aging Mouse Model

Frontiers in Aging Neuroscience, 2019
Microglia and astrocytes can quench metal toxicity to maintain tissue homeostasis, but with age, increasing glial dystrophy alongside metal dyshomeostasis may predispose the aged brain to acquire neurodegenerative diseases.
Azhaar Ashraf, Christos Michaelides, Thomas A. Walker, Antigoni Ekonomou, Maria Suessmilch, Achvini Sriskanthanathan, Semhar Abraha, Adam Parkes, Harold G. Parkes, Kalotina Geraki, Po-Wah So   +10 more
doaj   +1 more source

Ontogeny of synaptophysin and synaptoporin in the central nervous system [PDF]

, 1993
The expression of the synaptic vesicle antigens synaptophysin (SY) and synaptoporin (SO) was studied in the rat striatum, which contains a nearly homogeneous population of GABAergic neurons. In situ hybridization revealed high levels of SY transcripts in
B. Marquèze-Pouey, Bergmann, Betz, D. Grabs, Goldman-Rakic, Graybiel, H. Betz, Heimer, Hsu, I. Reisert, Iñiguez, Jahn, Jahn, Kita, Knaus, Lahr, Lauder, Leube, Lindefors, M. Bergmann, M. Gratzl, Marquèze-Pouey, Mugnaini, Newman-Gage, Olson, P. Knaus, Reiner, Reisert, Smith, Specht, Specht, Südhof, Thomas, Vernier, W. Ovtscharoff, Wiedenmann, Wilson   +36 more
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