Results 41 to 50 of about 117,260 (330)

Regional Distributions of Iron, Copper and Zinc and Their Relationships With Glia in a Normal Aging Mouse Model

Frontiers in Aging Neuroscience, 2019
Microglia and astrocytes can quench metal toxicity to maintain tissue homeostasis, but with age, increasing glial dystrophy alongside metal dyshomeostasis may predispose the aged brain to acquire neurodegenerative diseases.
Azhaar Ashraf, Christos Michaelides, Thomas A. Walker, Antigoni Ekonomou, Maria Suessmilch, Achvini Sriskanthanathan, Semhar Abraha, Adam Parkes, Harold G. Parkes, Kalotina Geraki, Po-Wah So   +10 more
doaj   +1 more source

Binary and nonbinary description of hypointensity for search and retrieval of brain MR images [PDF]

, 2009
Diagnosis accuracy in the medical field, is mainly affected by either lack of sufficient understanding of some diseases or the inter/intra-observer variability of the diagnoses.
Cetin, Mujdat, Chen, Xiaojing, Ekin, Ahmet, Ercil, Aytul, Erçil, Aytül, Jasinschi, Radu, Unay, Devrim, van Buchem, Mark A., Çetin, Müjdat, Ünay, Devrim   +9 more
core   +1 more source

Abnormal eye movements in three types of chorea

Arquivos de Neuro-Psiquiatria
Chorea is an abnormal movement characterized by a continuous flow of random muscle contractions. This phenomenon has several causes, such as infectious and degenerative processes. Chorea results from basal ganglia dysfunction.
Tiago Attoni, Rogério Beato, Serge Pinto, Francisco Cardoso   +3 more
doaj   +1 more source

Increased Basal Ganglia Modulatory Effective Connectivity Observed in Resting-State fMRI in Individuals With Parkinson’s Disease

Frontiers in Aging Neuroscience, 2022
Alterations to interactions between networked brain regions underlie cognitive impairment in many neurodegenerative diseases, providing an important physiological link between brain structure and cognitive function.
Nicholas J. Wapstra, Micah Ketola, Shelby Thompson, Adel Lee, Tara Madhyastha, Thomas J. Grabowski, Thomas J. Grabowski, Andrea Stocco   +7 more
doaj   +1 more source

Brain GABA and Glutamate Concentrations Following Chronic Gabapentin Administration: A Convenience Sample Studied During Early Abstinence From Alcohol. [PDF]

, 2018
Gabapentin (GBP), a GABA analog that may also affect glutamate (Glu) production, can normalize GABA and Glu tone during early abstinence from alcohol, effectively treating withdrawal symptoms and facilitating recovery.
Durazzo, Timothy C, Meyerhoff, Dieter J, Murray, Donna E, Pennington, David L   +3 more
core   +2 more sources

Apraxia and motor dysfunction in corticobasal syndrome [PDF]

, 2014
Background: Corticobasal syndrome (CBS) is characterized by multifaceted motor system dysfunction and cognitive disturbance; distinctive clinical features include limb apraxia and visuospatial dysfunction. Transcranial magnetic stimulation (TMS) has been
A Alberici, A Kertesz, A Kertesz, A Zwinkels, AA Kühn, AK Holl, Alessio Avenanti, B Borroni, B Okuda, BF Boeve, BF Boeve, BP Shelley, C Zadikoff, CD Good, D Claus, D Rueckert, DS Margulies, E De Renzi, E Frasson, E Mioshi, ED Huey, G Goldenberg, G Goldenberg, G Pengas, H Ling, J Ashburner, J Gottlieb, J Rohrer, J Valls-Solé, James R. Burrell, JL Whitwell, JM Cedarbaum, JO Rinne, John R. Hodges, JR Burrell, JR Burrell, JR Burrell, JR Burrell, K Tsuchiya, KA Josephs, KY Haaland, LJ Buxbaum, LJG Rothi, LR Robinson, M Heath, M Hornberger, M Pazzaglia, Matthew C. Kiernan, MC Kiernan, Michael Hornberger, NL Graham, NL Graham, P Soliveri, PK Pal, PP Pramstaller, PS Mathuranath, QJ Almeida, R Cantello, R Chen, R Leiguarda, R Leiguarda, R Mathew, R Mathew, RG Gross, RJ Fisher, RT Watson, S Vucic, S Vucic, S Vucic, S Vucic, SE Lee, SM Smith, SM Smith, Steve Vucic, T Fukui, U Ziemann, V Di Lazzaro, V Stamenova, Y Okuma, Y Zhang   +79 more
core   +3 more sources

Isolated Subtle Neurological Abnormalities in Mild Cognitive Impairment Types [PDF]

, 2020
Background: Isolated, subtle neurological abnormalities (ISNA) are commonly seen in aging and have been related to cerebral small vessel disease (SVD) and subcortical atrophy in neurologically and cognitively healthy aging subjects.
Azzarello, Delia, Camarda, Cecilia, Camarda, Rosolino, Cilluffo, Giovanna, Grassedonio, Emanuele, Pipia, Carmela, Sottile, Gianluca, Torelli, Paola   +7 more
core   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Neuroanatomical correlates of intelligence in healthy young adults: the role of basal ganglia volume.

PLoS ONE, 2014
BackgroundIn neuropsychiatric diseases with basal ganglia involvement, higher cognitive functions are often impaired. In this exploratory study, we examined healthy young adults to gain detailed insight into the relationship between basal ganglia volume ...
Cosima Rhein, Christiane Mühle, Tanja Richter-Schmidinger, Panagiotis Alexopoulos, Arnd Doerfler, Johannes Kornhuber   +5 more
doaj   +1 more source

Fahr’s syndrome and idiopathic hypoparathyroidism: A case report [PDF]

Vojnosanitetski Pregled, 2017
Introduction. Fahr´s syndrome is a rare, slowly progressive, neurodegenerative disorder, characterised by extensive, bilateral, and symmetrical basal ganglia calcification.
Marinković Dejan M., Dragović Tamara, Kiković Saša, Kuzmić-Janković Snežana, Đuran Zorana, Hajduković Zoran   +5 more
doaj   +1 more source