Results 71 to 80 of about 466,533 (289)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Energic metabolism studies in pediatric cancer patients

Медицинский вестник Юга России, 2010
The aim. To estimate heat capacity (C) measurements for individual dietary support of pediatric cancer patients during chemotherapy. Material and methods. 43 cancer children are examined.
M. V. Konovalova, A. Yu. Vashura, D. V. Litvinov, E. V. Skorobogatova, N. E. Filippova, S. V. Belmer, G. Ya. Tseitlin   +6 more
doaj  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Estimating the agreement between the metabolic rate calculated from prediction equations and from a portable indirect calorimetry device: an effort to develop a new equation for predicting resting metabolic rate

Nutrition & Metabolism, 2018
Background Many studies have been performed over time in order to determine the reliability of metabolic rate prediction equations. Purpose To evaluate the agreement, in terms of bias, absolute bias and accuracy between metabolic rate prediction ...
Eleni Pavlidou, Dimitris Petridis, Maria Tolia, Nikolaos Tsoukalas, Antigoni Poultsidi, Aristeidis Fasoulas, George Kyrgias, Constantinos Giaginis   +7 more
doaj   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Coping with Salt Water Habitats: Metabolic and Oxidative Responses to Salt Intake in the Rufous-Collared Sparrow

Frontiers in Physiology, 2017
Many physiological adjustments occur in response to salt intake in several marine taxa, which manifest at different scales from changes in the concentration of individual molecules to physical traits of whole organisms.
Pablo Sabat, Pablo Sabat, Cristóbal Narváez, Isaac Peña-Villalobos, Carolina Contreras, Karin Maldonado, Juan C. Sanchez-Hernandez, Seth D. Newsome, Roberto Nespolo, Francisco Bozinovic, Francisco Bozinovic   +10 more
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Effects of body composition on age- and sex-related differences in resting metabolic rate from a healthy aging cohort

Experimental Gerontology
Resting metabolic rate (RMR) accounts for the majority of the total energy expenditure. While RMR is known to decline with advancing age and is recognized to be lower in females compared to males, the mechanisms underlying these differences remain ...
Marcos Moliné, Stephanie R. Heimler, Jaclyn Bergstrom, Lina Scandalis, David Wing, Daniel Moreno, Howard J. Phang, Anthony J.A. Molina   +7 more
doaj   +1 more source

Phenotypic plasticity of metabolic rate in an afrotropical bird species (Euplectes orix) across a temperature gradient [PDF]

Avian species are known to have the capacity to respond to environmental changes through physiological adjustments. The process whereby organisms adjust their phenotype without genetic change is termed phenotypic plasticity and it is mostly observed to ...
Van de Ven, Tanja Maria Francisca Nicole
core   +1 more source