Results 71 to 80 of about 468,922 (330)
Hematopoietic (stem) cells—The elixir of life?
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
Handgrip strength is an indicator of general muscle strength. Low handgrip strength is associated with various diseases that can increase morbidity and mortality. Fat free mass and basal metabolic rate are indicators of health and physical fitness.
Noor Az Zhahra +3 more
doaj +1 more source
Adenovirus-mediated suppression of hypothalamic glucokinase affects feeding behavior [PDF]
Glucokinase (GK), the hexokinase involved in glucosensing in pancreatic β-cells, is also expressed in arcuate nucleus (AN) neurons and hypothalamic tanycytes, the cells that surround the basal third ventricle (3V).
Barahona, María José +10 more
core +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Energic metabolism studies in pediatric cancer patients
The aim. To estimate heat capacity (C) measurements for individual dietary support of pediatric cancer patients during chemotherapy. Material and methods. 43 cancer children are examined.
M. V. Konovalova +6 more
doaj
Background Many studies have been performed over time in order to determine the reliability of metabolic rate prediction equations. Purpose To evaluate the agreement, in terms of bias, absolute bias and accuracy between metabolic rate prediction ...
Eleni Pavlidou +7 more
doaj +1 more source
Avian Song Complexity is Associated With High Field Metabolic Rate [PDF]
Question: Is the production of bird song costly? Analyses of oxygen consumption during singing provided conflicting results. Data studied: Data on 28 passerine species with quantitative information on song complexity and field metabolic rate, which ...
Garamszegi, László Zsolt +2 more
core
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Many physiological adjustments occur in response to salt intake in several marine taxa, which manifest at different scales from changes in the concentration of individual molecules to physical traits of whole organisms.
Pablo Sabat +10 more
doaj +1 more source

