Results 111 to 120 of about 1,809,757 (282)

Circulating histones as clinical biomarkers in critically ill conditions

open access: yesFEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez   +17 more
wiley   +1 more source

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

open access: yesFEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao   +7 more
wiley   +1 more source

Change of Thiamine concentration and amino acid composition during sparkling wine base Production

open access: yesInternational Journal of Horticultural Science, 2001
It has been established, that thiamin content added in 3 mg/I concentration to musts before fermentation resulted in the enhanced storability of sparkling wine base at lower SO2 levels.
B. Pühra (Böröczki)   +2 more
doaj   +1 more source

Single‐cell insights into the role of T cells in B‐cell malignancies

open access: yesFEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

Tribology of Phenolic-based Composites

open access: yesSeikei-Kakou, 1992
Phenolic-based composites for automobile frictional materials contain a variety of inorganic fillers and modifiers in addition to the base resin and fibers (mostly asbestos). The frictional behavior at low speeds do not provide a sufficient foundation for the prediction of the friction and wear behavior at high speeds because the temperature rise at ...
Ikuo Narisawa   +2 more
openaire   +6 more sources

Flow‐based immunomagnetic enrichment of circulating tumor cells from diagnostic leukapheresis product

open access: yesMolecular Oncology, EarlyView.
The number of circulating tumor cells obtained from prostate cancer patients was increased approximately 5‐fold compared to regular CellSearch when processing 2 mL diagnostic leukapheresis material aliquots and increased by 44‐fold when processing 20 mL DLA aliquots using the flow enrichment target capture Halbach‐array.
Michiel Stevens   +8 more
wiley   +1 more source

Comprehensive analysis of the base composition around the transcription start site in Metazoa

open access: yesBMC Genomics, 2004
Background The transcription start site of a metazoan gene remains poorly understood, mostly because there is no clear signal present in all genes. Now that several sequenced metazoan genomes have been annotated, we have been able to compare the base ...
Moreau Yves   +4 more
doaj   +1 more source

BASAL CARDIAC FUNCTION AND BODY COMPOSITION WITH SPECIAL REFERENCE TO OBESITY 1 [PDF]

open access: bronze, 1952
Henry L. Taylor   +3 more
openalex   +1 more source

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