Results 71 to 80 of about 492,935 (306)

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Impact of Body Mass Index on Coordination, Static and Dynamic Balance in Young Adults: A Case-control Study [PDF]

Journal of Clinical and Diagnostic Research
Introduction: Abnormal Body Mass Index (BMI), characterised by a higher percentage of fat mass, has notable effects on postural control, leading to a forward shift in posture that exceeds the Base Of Support (BOS) boundary due to increased segmental mass
Ankita Debnath, Manish Kumar, Mamta Dagar, Vishwajeet Trivedi, Ashish Tyagi, AS Moorthy   +5 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Genome-wide nucleotide patterns and potential mechanisms of genome divergence following domestication in maize and soybean

Genome Biology, 2019
Background Plant domestication provides a unique model to study genome evolution. Many studies have been conducted to examine genes, genetic diversity, genome structure, and epigenome changes associated with domestication.
Jinyu Wang, Xianran Li, Kyung Do Kim, Michael J. Scanlon, Scott A. Jackson, Nathan M. Springer, Jianming Yu   +6 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Nest climate and blood quality of two host species of the ectoparasitic Philornis downsi in the Galapagos Islands as factors of larval development

Frontiers in Ecology and Evolution
The avian vampire fly is an invasive species on the Galapagos Islands, where its hematophagous larvae utilize nestling birds as hosts. It poses a serious threat to populations and species of Darwin finches and other avian species.
Courtney L. Pike, Rebecca Hood-Nowotny, Barbara Kofler, Heinz Richner, Sabine Tebbich   +4 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

The development of cream-mask base composition for androgenetic alopecia prevention and treatment

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2014
Aim. Androgenetic Alopecia (AA) treatment nowadays is still a difficult task of dermatology as the range of drugs that affect the pathological link of disease and are safe for prolonged use, is limited. Methods and results. The purpose of the work was
M. I. Fedorovska
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

The study of structural-mechanical characteristics of the ointment with aminexil

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2018
The estimation of rheological characteristics is an important and essential fragment of investigations for creating semisolid dosage forms for dermatologic practice.
Zhamaly Karym, V. V. Hladyshev, A. P. Lysianska   +2 more
doaj   +1 more source