Results 121 to 130 of about 40,087 (166)

Triple-negative complementary metamaterial for ultrasound transmission through elastic barrier. [PDF]

Sci Rep
Lee KY, Jeon W.
europepmc   +1 more source

Unraveling single-molecule reactions via multiplexed in-situ DNA sequencing

Hazra JP, Andrews R, Turner P, Zhao Q, Steuer H, El-Sagheer AH, Mazumder A, El Sayyed H, Kümmerlin M, Brown T, Kapanidis AN.   +10 more
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Pulling short DNA with mismatch base pairs

European Biophysics Journal, 2023
Due to misincorporation during gene replication, the accuracy of the gene expression is often compromised. This results in a mismatch or defective pair in the DNA molecule (James et al. 2016). Here, we present our study of the stability of DNA with defects in the thermal and force ensembles. We consider DNA with a different number of defects from 2to16
Navin Singh, Nehal Mathur
openaire   +2 more sources

Cytosine deamination in mismatched base pairs

Biochemistry, 1993
The rate of deamination of cytosine in mismatched base pairs has been determined. Incubation of M13mp2 nicked heteroduplex DNA molecules containing T.C or C.C mispairs in the lacZ alpha-complementation gene results in deamination of cytosine to uracil, producing T.U or C.U mispairs. Strands which have undergone deamination at the target site to produce
L A, Frederico, T A, Kunkel, B R, Shaw
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Dynamics of mismatched base pairs in DNA

Biochemistry, 1991
The structural dynamics of mismatched base pairs in duplex DNA have been studied by time-resolved fluorescence anisotropy decay measurements on a series of duplex oligodeoxynucleotides of the general type d[CGG(AP)GGC].d[GCCXCCG], where AP is the fluorescent adenine analogue 2-aminopurine and X = T, A, G, or C.
C R, Guest, R A, Hochstrasser, L C, Sowers, D P, Millar   +3 more
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Electrical current through DNA containing mismatched base pairs

Nanotechnology, 2010
Mismatched base pairs, such as different conformations of the G.A mispair, cause only minor structural changes in the host DNA molecule, thereby making mispair recognition an arduous task. Electron transport in DNA that depends strongly on the hopping transfer integrals between the nearest base pairs, which in turn are affected by the presence of a ...
Neranjan, Edirisinghe, Vadym, Apalkov, Julia, Berashevich, Tapash, Chakraborty   +3 more
openaire   +2 more sources

Unique magnetic signatures of mismatched base pairs in DNA

The Journal of Chemical Physics, 2010
Magnetic properties of DNA containing mispairs, such as different conformations of the G⋅A mispair, or a G⋅T mispair inserted into the DNA chain, have been theoretically investigated. The essential ingredients for these studies, the charge transfer integrals, were evaluated from the DNA sequences containing the mispair and optimized in the solvent.
Vadim, Apalkov, Julia, Berashevich, Tapash, Chakraborty   +2 more
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Base pair mismatch recognition using plasmon resonant particle labels

Analytical Biochemistry, 2002
We demonstrate the use of silver plasmon resonant particles (PRPs), as reporter labels, in a microarray-based DNA hybridization assay in which we screen for a known polymorphic site in the breast cancer gene BRCA1. PRPs (40-100 nm in diameter) image as diffraction-limited points of colored light in a standard microscope equipped with dark-field ...
Steven J, Oldenburg, Christine C, Genick, Keith A, Clark, David A, Schultz   +3 more
openaire   +2 more sources