Results 231 to 240 of about 41,285 (266)
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Excision and repair of mismatched base pairs in transformation of Streptococcus pneumoniae
Molecular and General Genetics MGG, 1980The use of heteroduplex DNA molecules as donors in pneumococcal transformation makes it possible to follow the fate of each DNA strand. The integration efficiency of each strand depends strongly upon the single base changes it carries. The function (hex) which reduces drastically the transformation yield of markers referred to as low efficiency (LE ...
J P, Claverys, M, Roger, A M, Sicard
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Effect of base pair mismatches on recombination via the RecBCD pathway
Molecular and General Genetics MGG, 1989The effect of base pair mismatches on recombination via the RecBCD pathway was studied in mutS and wild-type Escherichia coli, using substrates that contain single or multiple mismatches. Recombination between homologous DNA inserts in lambda phage and pBR322-derived plasmids forms phage-plasmid cointegrates that result from an odd numbers of ...
P, Shen, H V, Huang
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Biochemistry, 1988
High-resolution two-dimensional NMR studies have been completed on the self-complementary d(C-G-C-G-A-G-C-T-T-G-C-G) duplex (designated G.T 12-mer) and the self-complementary d(C-G-C-G-A-G-C-T-O4meT-G-C-G) duplex (designated G.O4meT 12-mer) containing G.T and G.O4meT pairs at identical positions four base pairs in from either end of the duplex.
Kalnik, M.W. +4 more
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High-resolution two-dimensional NMR studies have been completed on the self-complementary d(C-G-C-G-A-G-C-T-T-G-C-G) duplex (designated G.T 12-mer) and the self-complementary d(C-G-C-G-A-G-C-T-O4meT-G-C-G) duplex (designated G.O4meT 12-mer) containing G.T and G.O4meT pairs at identical positions four base pairs in from either end of the duplex.
Kalnik, M.W. +4 more
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Base pairing geometry in GA mismatches depends entirely on the neighboring sequence
Journal of Molecular Biology, 1992We have synthesized nine self-complementary DNA oligomers containing different flanking sequences adjacent to a pair of contiguous GA mismatches, and have used high resolution nuclear magnetic resonance (n.m.r.) to investigate the GpA phosphodiester backbone conformation and mismatch pairing schemes in these duplexes.
J W, Cheng, S H, Chou, B R, Reid
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Base pair mismatch recognition using plasmon resonant particle labels
Analytical Biochemistry, 2002We demonstrate the use of silver plasmon resonant particles (PRPs), as reporter labels, in a microarray-based DNA hybridization assay in which we screen for a known polymorphic site in the breast cancer gene BRCA1. PRPs (40-100 nm in diameter) image as diffraction-limited points of colored light in a standard microscope equipped with dark-field ...
Steven J, Oldenburg +3 more
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ChemInform Abstract: Recognition of Mismatched Base Pairs in DNA
ChemInform, 2009AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
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Isomerization Pathways of a Mismatched Base Pair of A:8OG in Free Duplex DNA
Journal of Chemical Information and ModelingThe A:8OG base pair (bp) is the outcome of DNA replication of the mismatched C:8OG bp. A high A:8OG bp population increases the C/G to A/T transversion mutation, which is responsible for various diseases. MutY is an important enzyme in the error-proof cycle and reverts A:8OG to C:8OG bp by cleaving adenine from the A:8OG bp.
Hyeonjun Kim, Youngshang Pak
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Base-pair mismatches in DNA fragments
Biochemical Society Transactions, 1986openaire +2 more sources