Results 111 to 120 of about 28,951,856 (408)

Base Pairing Interaction between 5′- and 3′-UTRs Controls icaR mRNA Translation in Staphylococcus aureus

PLoS Genetics, 2013
The presence of regulatory sequences in the 3′ untranslated region (3′-UTR) of eukaryotic mRNAs controlling RNA stability and translation efficiency is widely recognized.
Igor Ruiz de los Mozos, Marta Vergara-Irigaray, V. Segura, Maite Villanueva, N. Bitarte, M. Saramago, S. Domingues, C. Arraiano, P. Fechter, P. Romby, Jaione Valle, C. Solano, Í. Lasa, Alejandro Toledo-Arana   +13 more
semanticscholar   +1 more source

A cellular system to study responses to a collision between the transcription complex and a protein‐bound nick in the DNA template

FEBS Letters, EarlyView.
We present the cellular transcription‐coupled Flp‐nick system allowing the introduction of a Top1‐mimicking cleavage complex (Flpcc) at a Flp recognition target site within a controllable LacZ gene. LacZ transcription leads to the collision of RNA polymerase II (RNAPII) with Flpcc, and this causes RNAPII stalling, ubiquitination, and degradation.
Petra Herring, Morten Roedgaard, Camilla Myrup Holst, Helene Christensen, Birgitta R. Knudsen, Lotte Bjergbaek, Anni Hangaard Andersen   +6 more
wiley   +1 more source

Factor-4 and 6 compression of cyclotomic subgroups of and

Journal of Mathematical Cryptology, 2010
Bilinear pairings derived from supersingular elliptic curves of embedding degrees 4 and 6 over finite fields 𝔽2m and 𝔽3m, respectively, have been used to implement pairing-based cryptographic protocols.
Karabina Koray
doaj   +1 more source

Specific and non specific hybridization of oligonucleotide probes on microarrays [PDF]

, 2005
Gene expression analysis by means of microarrays is based on the sequence specific binding of mRNA to DNA oligonucleotide probes and its measurement using fluorescent labels. The binding of RNA fragments involving other sequences than the intended target
Binder, Hans, Preibisch, Stephan
core   +3 more sources

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

FEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke, Izadora Volpato Rossi, Marcel I. Ramirez   +2 more
wiley   +1 more source

Pairing symmetry in BiS$_{2}-$based superconductors [PDF]

arXiv, 2013
The possible pairing symmetries for BiS$_{2}-$based superconductors is investigated by using a minimal two-orbital model with onsite and nearest-neighbor intraorbital attractions $V_{0}$ and $V_{1}$, respectively. By using the mean-field approximation and solving the self-consistent equations, the phase diagram of the pairing symmetry is obtained.
arxiv  

Dissociation of ssDNA - Single-Walled Carbon Nanotube Hybrids by Watson-Crick Base Pairing

, 2010
The unwrapping event of ssDNA from the SWNT during the Watson-Crick base paring is investigated through electrical and optical methods, and binding energy calculations.
Brown S. D. M., Cha M., Changwon Park, Chen R. J., Chi Q., Gunn Kim, Heller D. A., Hersam M. C., Jeng E. S., Jisoon Ihm, Jiyong Park, Junghoon Lee, Kam N. W. S., Karachevtsev V. A., Kawamoto H., Kim W., Krupke R., Misun Cha, Namjo Jeong, Rashmi S. H., Saito R., Sambrooke J., Seungwon Jung, Sickert D., Staii C., Star A., Tu X., Wang W., Zhao X., Zheng M., Zheng M.   +30 more
core   +1 more source

The Ambiguous Base-Pairing and High Substrate Efficiency of T-705 (Favipiravir) Ribofuranosyl 5′-Triphosphate towards Influenza A Virus Polymerase

PLoS ONE, 2013
T-705 (Favipiravir) is a broad-spectrum antiviral molecule currently in late stage clinical development for the treatment of influenza virus infection.
Zhinan Jin, Lucas K. Smith, V. Rajwanshi, Baek Kim, J. Deval   +4 more
semanticscholar   +1 more source

DNA-Directed Base Pair Opening [PDF]

Molecules, 2012
Strand separation is a fundamental molecular process essential for the reading of the genetic information during DNA replication, transcription and recombination. However, DNA melting in physiological conditions in which the double helix is expected to be stable represents a challenging problem.
openaire   +7 more sources

STAT3 expression is reduced in cardiac pericytes in HFpEF and its loss reduces cellular adhesion and induces pericyte senescence

FEBS Letters, EarlyView.
Heart failure with preserved ejection fraction (HFpEF) accounts for half of the heart failure cases. It is characterised by microvascular dysfunction, associated with reduced pericyte coverage and diminished STAT3 expression in pericytes. Loss of STAT3 impairs pericyte adhesion, promotes senescence, and activates a pro‐fibrotic gene program.
Leah Rebecca Vanicek, Ariane Fischer, Mariano Ruz Jurado, Anita Tamiato, Tara Procida‐Kowalski, Jochen Wilhelm, Dennis Hecker, Maximilian Merten, Felicitas Escher, Badder Kattih, Valentina Puntmann, David John, Marcel H. Schulz, Eike Nagel, Stefanie Dimmeler, Guillermo Luxán   +15 more
wiley   +1 more source