Results 71 to 80 of about 342,669 (235)

Statistical mechanics of base stacking and pairing in DNA melting

, 2004
We propose a statistical mechanics model for DNA melting in which base stacking and pairing are explicitly introduced as distinct degrees of freedom. Unlike previous approaches, this model describes thermal denaturation of DNA secondary structure in the ...
A. Montrichok, C.R. Cantor, D. Cule, D. Marenduzzo, D.B. Naritsin, Giovanni Zocchi, V.A. Bloomfield, Vassili Ivanov, Yan Zeng   +8 more
core   +1 more source

Solving discrete logarithms on a 170-bit MNT curve by pairing reduction [PDF]

, 2016
Pairing based cryptography is in a dangerous position following the breakthroughs on discrete logarithms computations in finite fields of small characteristic.
A Commeine, A Guillevic, A Joux, A Joux, A Joux, A Menezes, A Miyaji, D Boneh, D Boneh, D Coppersmith, D Freeman, D Freeman, F Brezing, G Frey, IF Blake, J Beuchat, K Foster, LM Adleman, O Schirokauer, O Schirokauer, P Sarkar, P Sarkar, PSLM Barreto, R Barbulescu, R Barbulescu, R Barbulescu, R Dupont, R Granger, RM Elkenbracht-Huizing, SD Galbraith, T Hayashi, T Kim, Y Bistritz, Y Sakemi   +33 more
core   +5 more sources

Highly specific unnatural base pair systems as a third base pair for PCR amplification [PDF]

Nucleic Acids Research, 2011
Toward the expansion of the genetic alphabet of DNA, we present highly efficient unnatural base pair systems as an artificial third base pair for PCR. Hydrophobic unnatural base pair systems between 7-(2-thienyl)imidazo[4,5-b]pyridine (Ds) and 2-nitro-4-propynylpyrrole (Px) were fine-tuned for efficient PCR, by assessing the amplification efficiency ...
Akira Sato, Tsuneo Mitsui, Ichiro Hirao, Michiko Kimoto, Rie Yamashige, Yusuke Takezawa, Shigeyuki Yokoyama   +6 more
openaire   +3 more sources

A grafting strategy for the design of improved G-quadruplex aptamers and high-activity DNAzymes. [PDF]

PLoS ONE, 2009
Nucleic acid aptamers are generally obtained by in vitro selection. Some have G-rich consensus sequences with ability to fold into the four-stranded structures known as G-quadruplexes.
Tao Li, Erkang Wang, Shaojun Dong
doaj   +1 more source

Dissociation of ssDNA - Single-Walled Carbon Nanotube Hybrids by Watson-Crick Base Pairing

, 2010
The unwrapping event of ssDNA from the SWNT during the Watson-Crick base paring is investigated through electrical and optical methods, and binding energy calculations.
Brown S. D. M., Cha M., Changwon Park, Chen R. J., Chi Q., Gunn Kim, Heller D. A., Hersam M. C., Jeng E. S., Jisoon Ihm, Jiyong Park, Junghoon Lee, Kam N. W. S., Karachevtsev V. A., Kawamoto H., Kim W., Krupke R., Misun Cha, Namjo Jeong, Rashmi S. H., Saito R., Sambrooke J., Seungwon Jung, Sickert D., Staii C., Star A., Tu X., Wang W., Zhao X., Zheng M., Zheng M.   +30 more
core   +1 more source

Crowding-induced hybridization of single DNA hairpins [PDF]

, 2015
It is clear that a crowded environment influences the structure, dynamics, and interactions of biological molecules, but the complexity of this phenomenon demands the development of new experimental and theoretical approaches.
Baltierra-Jasso, Laura E., Laflor, Linda, Magennis, Steven W., Morten, Michael J., Quinn, Steven D.   +4 more
core   +2 more sources

Frequency and isostericity of RNA base pairs [PDF]

Nucleic Acids Research, 2009
Most of the hairpin, internal and junction loops that appear single-stranded in standard RNA secondary structures form recurrent 3D motifs, where non-Watson-Crick base pairs play a central role. Non-Watson-Crick base pairs also play crucial roles in tertiary contacts in structured RNA molecules.
Stombaugh, Jesse, Zirbel, Craig L., Westhof, Eric, Leontis, Neocles B.   +3 more
openaire   +4 more sources

Base‐Filling in Double‐Helical Nucleic Acids

ChemistryOpen
Base‐filling, i. e., post‐synthetic furnishing of an oligonucleotide scaffold with base moieties or their analogues, is an interesting alternative to the conventional approach of sequential coupling of building blocks (modified or otherwise).
Mark Nana Kwame Afari, Tuomas Lönnberg
doaj   +1 more source

Deligne's duality for de Rham realizations of 1-motives

, 2008
We show that the pairing on de Rham realizations of 1-motives in "Theorie di Hodge III", IHES 44, can be defined over any base scheme and we prove that it gives rise to a perfect duality if one is working with a 1-motive and its Cartier dual. Furthermore
Andreatta, Coleman, Coleman, Raynaud
core   +1 more source

Unusual Nucleic acid nanostructures based on G-quadruplex DNA

ACI Avances en Ciencias e Ingenierías, 2015
A nano-assembly based on non-canonical DNA structures is reported. For the nanofabrication of a DNA-based structure the self-assembly of guanine quadruplex (Hoogsteen base pairing) and double-stranded DNA (Watson-Crick base pairing) was exploited.
Miguel Angel Méndez
doaj   +1 more source