Results 71 to 80 of about 32,528,266 (371)
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa +3 more
wiley +1 more source
Selecting against accidental RNA interactions
eLife, 2016 Random base-pairing interactions between messenger RNAs and noncoding RNAs can reduce translation efficiency.
Meredith Corley, Alain Laederach
doaj +1 more source
Cis- and Trans-Encoded Small Regulatory RNAs in Bacillus subtilis
Microorganisms, 2021 Small regulatory RNAs (sRNAs) that act by base-pairing are the most abundant posttranscriptional regulators in all three kingdoms of life. Over the past 20 years, a variety of approaches have been employed to discover chromosome-encoded sRNAs in a ...
Sabine Brantl, Peter Müller
doaj +1 more source
Base Pairs to Populations [PDF]
Clinical Cancer Research, 2017 “There is much work to be done and many challenges exist in our mission to end the suffering that breast cancer brings.” So conclude Guest Editors Ann Partridge and Lisa Carey in their overview for this CCR Focus on breast cancer.
openaire +2 more sources
, 2012 We give an explicit formula relating the dynamical adjoint functor and dynamical twist over nonalbelian base to the invariant pairing on parabolic Verma modules. As an illustration, we give explicit $U(sl(n))$- and $U_\hbar(sl(n))$-invariant star product
A Alekseev +12 more
core +1 more source
Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Base‐Filling in Double‐Helical Nucleic Acids
ChemistryOpenBase‐filling, i. e., post‐synthetic furnishing of an oligonucleotide scaffold with base moieties or their analogues, is an interesting alternative to the conventional approach of sequential coupling of building blocks (modified or otherwise).
Mark Nana Kwame Afari, Tuomas Lönnberg
doaj +1 more source
Base pair probability estimates improve the prediction accuracy of RNA non-canonical base pairs. [PDF]
PLoS Computational Biology, 2017 Prediction of RNA tertiary structure from sequence is an important problem, but generating accurate structure models for even short sequences remains difficult.
Michael F Sloma, David H Mathews
doaj +1 more source
Absence of extended states in a ladder model of DNA [PDF]
, 2006 We consider a ladder model of DNA for describing carrier transport in a fully coherent regime through finite segments. A single orbital is associated to each base, and both interstrand and intrastrand overlaps are considered within the nearest-neighbor ...
Diaz, E. +3 more
core +3 more sources
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source