Results 101 to 110 of about 3,508,819 (309)

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Influência da saturação por bases e do fósforo no crescimento de mudas de angico-branco Influence of base saturation and phosphorus on the development of angico-branco seedlings

Revista Árvore, 2004
Este trabalho teve por objetivo avaliar o desempenho de mudas da espécie angico-branco (Anadenanthera colubrina (Vell.) Brenan), em condições diferenciadas de disponibilidade de fósforo no solo e de saturação por bases. Os tratamentos foram representados
Keli Cristina de Oliveira Gomes, Haroldo Nogueira de Paiva, Júlio César Lima Neves, Nairam Félix de Barros, Sérgio Ricardo Silva   +4 more
doaj   +1 more source

A note on the Monte Carlo assessment of Impulse Saturation with fat tailed distribution [PDF]

Monte Carlo evidence is provided as to the efficiency of the impulse saturation estimator in a location-scale model with heavy-tailed distributions. Comparisons show that the IS estimator is always more efficient than the OLS and can even outperform the ...
Carlos Santos
core  

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

Effects of soil and climatic factors on the potential distribution of Castanopsis eyrei in China

Frontiers in Plant Science
The geographical distributions of plant species are being actively reshaped by climate change. Castanopsis eyrei, a cornerstone species of subtropical evergreen broad-leaved forests in China, plays a critical role in community assembly and carbon ...
Jingjing Cao, Huipeng Yang, Yutong Xia, Shixin Zhang, Yao Li, Yanming Fang   +5 more
doaj   +1 more source

Base saturation and corn hybrids under no-tillage system

, 2001
O conhecimento dos híbridos adaptados a cada condição de reação do solo em sistema plantio direto é de significativa importância técnica. Para avaliar o comportamento de híbridos de milho sob sistema plantio direto, quanto a alguns componentes de ...
Prado,Renato de Mello, Prado, Renato de Mello, Prado, Renato De Mello [UNESP]   +2 more
core   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

CATION EXCHANGE CAPACITY OF DOMINANT SOIL TYPES IN THE REPUBLIC OF CROATIA [PDF]

Journal of Central European Agriculture, 2013
The study was conducted on 18 locations and 11 dominant soil types in the Republic of Croatia including their evolution-genetic horizons. In total, 51 soil samples were examined.
Marija Tomasic, Zeljka Zgorelec, Aleksandra Jurisic, Ivica Kisic   +3 more
doaj  

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source