Results 61 to 70 of about 677,760 (302)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

On sets of graded attribute implications with witnessed non-redundancy

, 2015
We study properties of particular non-redundant sets of if-then rules describing dependencies between graded attributes. We introduce notions of saturation and witnessed non-redundancy of sets of graded attribute implications are show that bases of ...
Vychodil, Vilem
core   +1 more source

Effect of sedimentary heterogeneities in the sealing formation on predictive analysis of geological CO₂ storage [PDF]

, 2019
Numerical models of geologic carbon sequestration (GCS) in saline aquifers use multiphase fluid flow-characteristic curves (relative permeability and capillary pressure) to represent the interactions of the non-wetting CO2 and the wetting brine. Relative
Alkan, Amann-Hildenbrand, Amann-Hildenbrand, Anderson, André, Armitage, Bachu, Bastin, Bear, Bennion, Bielicki, Birkholzer, Birkholzer, Bloomfield, Brooks, Burnside, Cameron, Carsel, Class, Deng, Dewhurst, Dewhurst, Doughty, Ducellier, Folk, Handin, Harrington, Hayley Vosper, Hobbs, Howard, IEAGHG, IPCC, John D.O. Williams, Kaldi, Khan, Lenhard, Liu, Michael U. Onoja, Middleton, Miri, Mori, Newell, Nicot, Niemi, Noy, Okwen, Oldenburg, Onoja, Oostrom, Orlic, Orr, Peters, Rutqvist, Rutqvist, Schlumberger, Seedhouse, Seyed M. Shariatipour, Shariatipour, Shariatipour, Shukla, Smith, Standing, Stow, Van Genuchten, Vilarrasa, Williams, Yamamoto, Yang, Yang, Zhang   +69 more
core   +2 more sources

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Soil acidity levels for blackberry liming recommendation and yield increase

Pesquisa Agropecuária Brasileira
The objective of this work was to determine the acidity levels to obtain adequate soil chemical attributes for the maximum fruit yield of blackberry trees grown in acidic soils subjected to increasing limestone rates.
Enilson de Barros Silva, Ramony Cristina Lima, Jéssica Oliveira Gaurat, Ari Medeiros Braga Neto, Maria do Céu Monteiro da Cruz, Dalila Costa Aparecida Bié, Emerson Dias Gonçalves, Luiz Fernando de Oliveira Silva, Pedro Henrique Abreu Moura, Shirley Macedo de Souza   +9 more
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

The Reactions of Common Chemical Fertilizers in An Ultisol and Their Effects on Cowpea Performance

Journal of Tropical Soils, 2019
Chemical fertilizers (CF) are the major input on arable farms in Nigeria. Current increasing rate of nutrient depletion in CF treated soils calls for the need to study their reactions in soils. To achieve this, three CF based treatments, namely NPK 15:15:
Oyeyiola Yetunde Bunmi, Omueti John Ajayi   +1 more
doaj   +1 more source

Pemberian Bahan Amandemen Untuk Perbaikan Retensi Hara Tanaman Jeruk Manis (Citrus Sinensis L.) Di Desa Talimbaru Kecamatan Barusjahe Kabupaten Karo [PDF]

, 2016
This study aimed to determine the diverification of the amendment to the base saturation and production of sweet orange. This research was conducted in plantation citrus Talimbaru Village Barusjahe District Regency of Karo with plant age of ± five years ...
Pakpahan, R. I. (Rina), Sarifuddin, S. (Sarifuddin), Supriadi, S. (Supriadi)   +2 more
core  

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Accuracy of methods to estimate potential acidity and lime requirement in soils of west region of Santa Catarina

Ciência Rural, 2018
: The objective of this study was to compare two methods of evaluation of potencial acidity (H+Al) and two methods to estimate liming requirement (LR) for soils from the west region of Santa Catarina State, Brazil.
Rodrigo Predebon, Luciano Colpo Gatiboni, Gilmar Luiz Mumbach, Djalma Eugenio Schmitt, Daniel João Dall’Orsoletta, Gustavo Brunetto   +5 more
doaj   +1 more source