Results 61 to 70 of about 685,157 (352)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Rapid and Quantitative Chemical Exchange Saturation Transfer (CEST) Imaging with Magnetic Resonance Fingerprinting (MRF)

, 2017
Purpose: To develop a fast magnetic resonance fingerprinting (MRF) method for quantitative chemical exchange saturation transfer (CEST) imaging. Methods: We implemented a CEST-MRF method to quantify the chemical exchange rate and volume fraction of the
Cohen, Ouri, Farrar, Christian T., Huang, Shuning, McMahon, Michael T., Rosen, Matthew S.   +4 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Pemberian Bahan Amandemen Untuk Perbaikan Retensi Hara Tanaman Jeruk Manis (Citrus Sinensis L.) Di Desa Talimbaru Kecamatan Barusjahe Kabupaten Karo [PDF]

, 2016
This study aimed to determine the diverification of the amendment to the base saturation and production of sweet orange. This research was conducted in plantation citrus Talimbaru Village Barusjahe District Regency of Karo with plant age of ± five years ...
Pakpahan, R. I. (Rina), Sarifuddin, S. (Sarifuddin), Supriadi, S. (Supriadi)   +2 more
core  

Three-dimensional instabilities and transition of steady and pulsatile axisymmetric stenotic flows [PDF]

, 2005
Published ...
Blackburn, HM, Sherwin, SJ
core   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Soil acidity levels for blackberry liming recommendation and yield increase

Pesquisa Agropecuária Brasileira
The objective of this work was to determine the acidity levels to obtain adequate soil chemical attributes for the maximum fruit yield of blackberry trees grown in acidic soils subjected to increasing limestone rates.
Enilson de Barros Silva, Ramony Cristina Lima, Jéssica Oliveira Gaurat, Ari Medeiros Braga Neto, Maria do Céu Monteiro da Cruz, Dalila Costa Aparecida Bié, Emerson Dias Gonçalves, Luiz Fernando de Oliveira Silva, Pedro Henrique Abreu Moura, Shirley Macedo de Souza   +9 more
doaj   +1 more source

The Reactions of Common Chemical Fertilizers in An Ultisol and Their Effects on Cowpea Performance

Journal of Tropical Soils, 2019
Chemical fertilizers (CF) are the major input on arable farms in Nigeria. Current increasing rate of nutrient depletion in CF treated soils calls for the need to study their reactions in soils. To achieve this, three CF based treatments, namely NPK 15:15:
Oyeyiola Yetunde Bunmi, Omueti John Ajayi   +1 more
doaj   +1 more source

A systematic numerical study of the tidal instability in a rotating triaxial ellipsoid [PDF]

, 2010
The full non-linear evolution of the tidal instability is studied numerically in an ellipsoidal fluid domain relevant for planetary cores applications.
Aldridge, Bayly, Benton, Boubnov, Chan, Craik, D. Cébron, Eloy, Eloy, Gledzer, Gledzer, Gledzer, Greenspan, Haj-Hariri, Herreman, Hollerbach, Hough, J. Leontini, Kelvin, Kerswell, Kerswell, Kerswell, Lacaze, Lacaze, Lacaze, Lacaze, Lainey, Le Bars, Le Bars, Le Dizès, Le Dizès, Leblanc, Leblanc, Leweke, Leweke, Lundgren, M. Le Bars, Malkus, Mason, McAlister, Meunier, Moore, Munk, P. Le Gal, P. Maubert, Pierrehumbert, Poincaré, Potylitsin, Rieutord, Roy, Seyed-Mahmoud, Seyed-Mahmoud, Shangli, Sipp, Sipp, Thess, Touma, Vladimirov, Waleffe, Widnall, Williams   +60 more
core   +6 more sources

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source