Results 91 to 100 of about 905,353 (315)
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Almost multiphase sequences based on Chu sequences
Electronics Letters, 2015 A new family of almost multiphase sequences (AMPSs) with perfect periodic autocorrelation function (PACF) is offered. The obtained sequences are based on Chu sequences and differ from them by the structure, the peak‐factor which is nearly equal to one, and by fewer phases for the same periods.
V.E. Gantmakher, M.V. Zaleshin
openaire +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
PCR Mutagenesis-Based Method for Generation of Positive Controls for SSCP Analysis
BioTechniques, 1997 We have developed a primer-mediated PCR mutagenesis-based method for the generation of positive controls to test the sensitivity of single-strand conformation polymorphism (SSCP) or any other PCRbased mutation screening method. This technique is based on
A. Ruiz +4 more
doaj +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Synchronizable Checking Sequences Based on UIO Sequences [PDF]
, 1996 This study addresses the synchronization problem that arises during the application of a predetermined checking sequence in some protocol test architectures that utilize remote testers. The synchronization problem can usually be solved by adding an additional communication channel or an additional protocol for coordination between the remote testers ...
S. Guyot, H. Ural
openaire +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
A Robust Deep Learning Ensemble-Driven Model for Defect and Non-Defect Recognition and Classification Using a Weighted Averaging Sequence-Based Meta-Learning Ensembler [PDF]
, 2022 Okeke Stephen +2 more
openalex +1 more source
AbstractLearning from time series data is an essential component in the AI landscape given the ubiquitous time-dependent data in real-world applications. To motivate the necessity of learning from time series data, we first introduce different applications, data sources, and properties.
Christoffer Loeffler +4 more
openaire +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source