Results 91 to 100 of about 31,885,483 (388)
In phylogenetic analyses of nucleotide sequences, ‘homogeneous’ substitution models, which assume the stationarity of base composition across a tree, are widely used, albeit individual sequences may bear distinctive base frequencies.
Sohta A. Ishikawa+2 more
doaj +1 more source
Sequence-specific double-strand cleavage of DNA by penta-N-methylpyrrolecarboxamide-EDTA·Fe(II) [PDF]
In the presence of O2 and 5 mM dithiothreitol, penta-N-methylpyrrolecarboxamide-EDTA·Fe(II) [P5E·Fe(II)] at 0.5 µ M cleaves pBR322 plasmid DNA (50 µ M in base pairs) on opposite strands to afford discrete DNA fragments as analyzed by agarose gel ...
Dervan, Peter B., Schultz, Peter G.
core
On the last nonzero digits of $n!$ in a given base
In this paper we study the sequence of strings of $k$ last nonzero digits of $n!$ in a given base $b$. We determine for which $b$ this sequence is automatic and show how to generate it using a uniform morphism.
Sobolewski, Bartosz
core +1 more source
Hermansky‐Pudlak syndrome type 1 (HPS‐1) is a rare, autosomal recessive disorder with poorly understood renal involvement. Urinary extracellular vesicle (uEV) proteomics and a novel Hps1 mouse model reveal mitochondrial abnormalities and lipid accumulation in HPS‐1 kidney proximal tubule cells. Serum ApoA1 correlates with kidney function in our patient
Dawn M. Maynard+7 more
wiley +1 more source
Background A transcriptional reporter is the key component in bacterial biosensors which are employed to monitor the induction or repression of a reporter gene corresponding to environmental change.
Xingjuan Chen+8 more
doaj +1 more source
Some integer sequences based on derangements [PDF]
Sequences whose terms are equal to the number of functions with specified properties are considered. Properties are based on the notion of derangements in a more general sense. Several sequences which generalize the standard notion of derangements are thus obtained.
arxiv
Integrating alignment-based and alignment-free sequence similarity measures for biological sequence classification [PDF]
Alignment-based sequence similarity searches, while accurate for some type of sequences, can produce incorrect results when used on more divergent but functionally related sequences that have undergone the sequence rearrangements observed in many bacterial and viral genomes. Here, we propose a classification model that exploits the complementary nature
arxiv +1 more source
The RNA genome of hepatitis C virus (HCV) terminates with a highly conserved 98-base sequence. Enzymatic and chemical approaches were used to define the secondary structure of this 3'-terminal element in RNA transcribed in vitro from cloned cDNA.
K. Blight, Charles M. Rice
semanticscholar +1 more source
We describe a novel set of Epac‐based FRET‐FLIM biosensors with improved fully cytosolic distribution, achieved without compromising the state‐of‐the‐art performance of our original designs, for detecting cAMP dynamics in real time in live cells with high precision and reliability.
Giulia Zanetti+2 more
wiley +1 more source
We performed mitogenome analysis of Japanese firefly Luciola cruciata (Coleoptera: Lampyridae), which is unique species in Japan. It is classified into six haplotypes based on the difference of COII sequence on mitochondrial DNA.
Juri Maeda+5 more
doaj +1 more source