Results 91 to 100 of about 2,847,295 (322)

On the Fuzzy Convergence

Journal of Applied Mathematics, 2011
The aim of this paper is to introduce and study the fuzzy neighborhood, the limit fuzzy number, the convergent fuzzy sequence, the bounded fuzzy sequence, and the Cauchy fuzzy sequence on the base which is adopted by Abdul Hameed (every real number r is ...
Abdul Hameed Q. A. Al-Tai
doaj   +1 more source

High-throughput sequencing of core STR loci for forensic genetic investigations using the Roche Genome Sequencer FLX platform

BioTechniques, 2011
The analysis and profiling of short tandem repeat (STR) loci is routinely used in forensic genetics. Current methods to investigate STR loci, including PCR-based standard fragment analyses and capillary electrophoresis, only provide amplicon lengths that
Sarah L. Fordyce, Maria C. Ávila-Arcos, Eszter Rockenbauer, Claus Børsting, Rune Frank-Hansen, Frederik Torp Petersen, Eske Willerslev, Anders J. Hansen, Niels Morling, M. Thomas. P. Gilbert   +9 more
doaj   +1 more source

Novel CRISPR-based sequence specific enrichment methods for target loci and single base mutations.

PLoS ONE, 2020
The programmable sequence specificity of CRISPR has found uses in gene editing and diagnostics. This manuscript describes an additional application of CRISPR through a family of novel DNA enrichment technologies.
Jennifer L Steele, Richard C Stevens, Oscar A Cabrera, Gary J Bassill, Sabrina M Cramer, Felipe Guzman, Anthony P Shuber   +6 more
doaj   +1 more source

Intron‐oriented HTLV‐1 integration in an adult T‐cell leukemia/lymphoma cell line sustains expression of intact ift81 mRNA

FEBS Letters, EarlyView.
In the adult T‐cell leukemia/lymphoma (ATL) cell line ED, the human T‐cell leukemia virus type 1 (HTLV‐1) provirus was integrated into the intron of the ift81 gene in the antisense orientation. Despite this integration, both the intact ift81 and the viral oncogene hbz were simultaneously expressed, likely due to the functional insufficiency of viral ...
Mayuko Yagi, Yuka Hirosawa, Yusaku Sagisaka, Minami Hama, Satoshi Takeda, Jun A. Komano   +5 more
wiley   +1 more source

TRAF2 binds to TIFA via a novel motif and contributes to its autophagic degradation

FEBS Letters, EarlyView.
TRAF family members couple receptor signalling complexes to downstream outputs, but how they interact with these complexes is not always clear. Here, we show that during ADP‐heptose signalling, TRAF2 binding to TIFA requires two short sequence motifs in the C‐terminal tail of TIFA, which are distinct from the TRAF6 binding motif.
Tom Snelling, Kodi Hunter, Celest W. S. Tay, Nicola T. Wood, Philip Cohen   +4 more
wiley   +1 more source

Low Base-Substitution Mutation Rate but High Rate of Slippage Mutations in the Sequence Repeat-Rich Genome of Dictyostelium discoideum

G3: Genes, Genomes, Genetics, 2020
We describe the rate and spectrum of spontaneous mutations for the social amoeba Dictyostelium discoideum, a key model organism in molecular, cellular, evolutionary and developmental biology. Whole-genome sequencing of 37 mutation accumulation lines of D.
Sibel Kucukyildirim, Megan Behringer, Way Sung, Debra A. Brock, Thomas G. Doak, Hatice Mergen, David C. Queller, Joan E. Strassmann, Michael Lynch   +8 more
doaj   +1 more source

A repetitive sequence assembler based on next-generation sequencing

Genetics and Molecular Research, 2016
Repetitive sequences of variable length are common in almost all eukaryotic genomes, and most of them are presumed to have important biomedical functions and can cause genomic instability. Next-generation sequencing (NGS) technologies provide the possibility of identifying capturing these repetitive sequences directly from the NGS data.
Y Wang, Y Tu, Xinwu Chen, Shuaibin Lian, Ling-Ling Wang   +4 more
openaire   +3 more sources

Application of Sequence Embedding in Protein Sequence-Based Predictions

, 2022
In sequence-based predictions, conventionally an input sequence is represented by a multiple sequence alignment (MSA) or a representation derived from MSA, such as a position-specific scoring matrix. Recently, inspired by the development in natural language processing, several applications of sequence embedding have been observed.
Ibtehaz, Nabil, Kihara, Daisuke
openaire   +2 more sources

Goodbye flat lymphoma biology

FEBS Letters, EarlyView.
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria, Cèlia Dobaño‐López, Patricia Pérez‐Galán, Christine Bezombes   +3 more
wiley   +1 more source

Almost multiphase sequences based on Chu sequences

Electronics Letters, 2015
A new family of almost multiphase sequences (AMPSs) with perfect periodic autocorrelation function (PACF) is offered. The obtained sequences are based on Chu sequences and differ from them by the structure, the peak‐factor which is nearly equal to one, and by fewer phases for the same periods.
V.E. Gantmakher, M.V. Zaleshin
openaire   +2 more sources