Results 191 to 200 of about 2,954,117 (341)

ARROW: Allele-Specific Recombined gRNA Design for Reduced Off-Target with Enhanced Specificity. [PDF]

Bioengineering (Basel)
Bae T, Been KW, Kang S, Hong S, Hur JK, Hwang W.   +5 more
europepmc   +1 more source

Contributions of the Petabyte Scale Sequence Search Codeathon toward efforts to scale sequence-based searches on SRA [PDF]

Kjiersten Fagnan, Ryan Connor, Ravinder Pannu, Travis J. Wheeler, Mihai Pop, C. Titus Brown, Rob Patro, Jacquelyn S. Michaelis, Thomas Madden, Arianna I. Krinos, René K. M. Xavier, R Polo, Jack W Roddy, Adrian Viehweger, Barış Ekim, Harihara Subrahmaniam Muralidharan, Vinícius W. Salazar, Andrew Tritt, Katrina Kalantar, George T. Lesica, Artem Babaian, Vadim Zalunin, David M. Kristensen, Alexa Salsbury, Daniel P. Rice   +24 more
openalex   +1 more source

Dynamic Outlier Exclusion Training Algorithm for Sequence Based Predictions in Proteins Using Neural Network [PDF]

, 2007
Shandar Ahmad
openalex   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

MethPy: a new software for analyzing non-CpG methylation after bisulfite assay and Sanger sequencing. [PDF]

Sci Rep
Roiati M, Borges LDF, Cattani A, Lucarelli M, Fuso A.   +4 more
europepmc   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

RNA inverse folding can be solved in linear time for structures without isolated stacks or base pairs. [PDF]

Algorithms Mol Biol
Boury T, Gardelle S, Bulteau L, Ponty Y.
europepmc   +1 more source

Molecular phylogeny of the tree genus Populus (Salicaceae) based on chloroplast and nuclear DNA sequence data [PDF]

, 2003
Mona Hamzeh
openalex  

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Noncoding RNA family classification based on multifeature fusion and convolutional block attention residual network. [PDF]

Brief Bioinform
Xu Q, Li F, Han G.
europepmc   +1 more source