Results 201 to 210 of about 2,954,117 (341)

Real-Time Nucleic Acid Sequence-Based Amplification Is More Convenient than Real-Time PCR for Quantification of Plasmodium falciparum

, 2005
Petra Schneider, Liselotte Wolters, Gerard J. Schoone, Henk D. F. H. Schallig, Peter Sillekens, Rob Hermsen, Robert W. Sauerwein   +6 more
openalex   +2 more sources

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Twin Small RNAs and Divergent Fates: The Expansive Regulatory Networks of OmrA and OmrB. [PDF]

Int J Mol Sci
Konarska J, Jaworska K, Lipska P, Raczkowska A.   +3 more
europepmc   +1 more source

HOS-based image sequence noise removal

, 2006
Mohammed El Hassouni, Hocine Cherifi, D. Aboutajdine   +2 more
openalex   +2 more sources

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Engineering a CRISPR-associated IscB system for developing miniature genome-editing tools in human cells and mouse embryos. [PDF]

Nat Commun
Zhang F, Peng Y, Fan D, Song G, Gao X, Tian Y.   +5 more
europepmc   +1 more source

Extraordinary stable structure of short single-stranded DNA fragments containing a specific base sequence: d(GCGAAAGC)

, 1989
Ichiro Hirao, Yoshifumi Nishimura, Tetsushi Naraoka, Kimutsuna Watanabe, Yoji Arata, Kin‐ichiro Miura   +5 more
openalex   +2 more sources

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Deep learning models simultaneously trained on multiple datasets improve base-editing activity prediction. [PDF]

Nat Commun
Sun Y, Qu K, Corsi GI, Anthon C, Pan X, Xiang X, Jensen LJ, Lin L, Luo Y, Gorodkin J.   +9 more
europepmc   +1 more source