Results 251 to 260 of about 31,885,483 (388)

Two improved promoter sequences for the β-lactamase expression arising from a single base-pair substitution [PDF]

, 1984
Shin‐Tai Chen, Royston C. Clowes
openalex   +1 more source

Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance

Molecular Oncology, EarlyView.
Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...
Hendrika A. Segeren, Kathryn A. Wierenga, Frank M. Riemers, Elsbeth A. van Liere, Bart Westendorp   +4 more
wiley   +1 more source

First draft genome sequence data of TA4-1, the type strain of Gram-positive bacterium Streptomyces chiangmaiensis

Data in Brief
TA4-1 is the type strain of Streptomyces chiangmaiensis. The TA4-1 strain was isolated from a stingless bee (Tetragonilla collina). Here we present the draft genome sequence data of S. chiangmaiensis TA4-1.
Montri Yasawong, A'liyatur Rosyidah, Thunwarat Songngamsuk, Manassanan Phatcharaharikarn, Phongsakorn Ganta, Panjamaphon Chanthasena, Nuannoi Chudapongse, Napatsorn Santapan, Wissarut Srisakvarangkool, Supavadee Kerdtoob, Nawarat Nantapong   +10 more
doaj  

GoldPolish-target: targeted long-read genome assembly polishing. [PDF]

BMC Bioinformatics
Zhang E, Coombe L, Wong J, Warren RL, Birol I.   +4 more
europepmc   +1 more source

Targeting PRAME directly or via EZH2 inhibition overcomes retinoid resistance and represents a novel therapy for keratinocyte carcinoma

Molecular Oncology, EarlyView.
The study evaluated the function and therapeutic implications of PRAME in basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). The findings demonstrate that PRAME impairs keratinocyte differentiation pathways. Furthermore, PRAME impairs anticancer response to retinoid compounds in BCC and SCC cells.
Brandon Ramchatesingh, Amelia Martinez Villarreal, Philippe Lefrançois, Jennifer Gantchev, Sriraam Sivachandran, Samy Abou Setah, Ivan V. Litvinov   +6 more
wiley   +1 more source

Difference Analysis Among Six Kinds of Acceptor Splicing Sequences by the Dispersion Features of 6-mer Subsets in Human Genes. [PDF]

Biology (Basel)
Si Y, Li H, Li X.
europepmc   +1 more source

c-fos sequence necessary for basal expression and induction by epidermal growth factor, 12-O-tetradecanoyl phorbol-13-acetate and the calcium ionophore.

, 1987
T M Fisch, Ron Prywes, R G Roeder
openalex   +1 more source

Plant small nuclear RNAs. V. U4 RNA is present in broad bean plants in the form of sequence variants and is base-paired with U6 RNA [PDF]

, 1988
Tamás Kiss, Gábor Jakab, Mária Antal, Zsófia Pálfi, Hedvig Hegyi, Mihály Kis, Ferenc Solymosy   +6 more
openalex   +1 more source

CircCCNB1 inhibits vasculogenic mimicry by sequestering NF90 to promote miR‐15b‐5p and miR‐7‐1‐3p processing in nasopharyngeal carcinoma

Molecular Oncology, EarlyView.
CircCCNB1 expression is down‐regulated in nasopharyngeal carcinoma (NPC); thus, less NF90 protein is bound to circCCNB1 and more binds to pri‐miRNAs, blocking their (pri‐miRNAs) binding to DGCR8 and inhibiting the processing and generation of miR‐15b‐5p/miR‐7‐1‐3p. Furthermore, decreased miR‐15b‐5p/miR‐7‐1‐3p promotes the expression of the target genes
Chunmei Fan, Fenghua Tan, Jie Wu, Zhaoyang Zeng, Wenjia Guo, He Huang, Wei Xiong   +6 more
wiley   +1 more source

Engineered circular guide RNAs enhance miniature CRISPR/Cas12f-based gene activation and adenine base editing. [PDF]

Nat Commun
Zhang X, Li M, Chen K, Liu Y, Liu J, Wang J, Huang H, Zhang Y, Huang T, Ma S, Liao K, Zhou J, Wang M, Lin Y, Rong Z.   +14 more
europepmc   +1 more source