Results 281 to 290 of about 2,954,117 (341)

Base composition at the start of the coding sequence controls the balance between translation initiation and mRNA degradation in E. coli. [PDF]

open access: yesNucleic Acids Res
Lipońska A   +8 more
europepmc   +1 more source

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

open access: yesFEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul   +3 more
wiley   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

Double-stranded DNA deaminase DddA<sup>E1347A</sup> can increase the efficiency and targeting range of cytidine base editors. [PDF]

open access: yesGenome Biol
Qian Y   +14 more
europepmc   +1 more source

Exploiting nanopore sequencing advances for tRNA sequencing of human cancer models. [PDF]

open access: yesNAR Cancer
Kochavi A   +6 more
europepmc   +1 more source

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