Monoclonal antibody-based, selective isolation of DNA fragments containing an alkylated base to be quantified in defined gene sequences [PDF]
Klaus Hochleitner+3 more
openalex +1 more source
On the extension of basic sequences to bases [PDF]
openaire +3 more sources
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim+8 more
wiley +1 more source
Efficient mutagenesis and genotyping of maize inbreds using biolistics, multiplex CRISPR/Cas9 editing, and Indel-Selective PCR. [PDF]
Rai MN+6 more
europepmc +1 more source
Cleavage at the twelve-base-pair sequence 5′-TCTAGATCTAGA-3′ using M·Xbal(TCTAGm6A) methylation andDpnl(Gm6A/TC) cleavage [PDF]
Yogesh Patel+3 more
openalex +1 more source
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka+10 more
wiley +1 more source
The Unpaved Road of Non-Coding RNA Structure-Function Relationships: Current Knowledge, Available Methodologies, and Future Trends. [PDF]
Leitão AL, Enguita FJ.
europepmc +1 more source
Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu+15 more
wiley +1 more source
Molecular characterization of virulent genes in Pseudomonas aeruginosa based on componential usage divergence. [PDF]
Huang Q, Yan K, Li G.
europepmc +1 more source