Results 121 to 130 of about 2,679,856 (365)

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

High temperature cyclic oxidation data. Part 1: Turbine alloys [PDF]

open access: yes
Specific-weight-change-versus-time data and x ray diffraction results are presented derived from high temperature cyclic tests on high temperature, high strength nickel-base gamma/gamma prime and cobalt-base turbine alloys. Each page of data summarizes a
Barrett, Charles A.   +2 more
core   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

Estimation of ground temperature from GFCR radiometric signal [PDF]

open access: yes
A procedure was developed which demonstrates the feasibility of estimating actual surface temperature from the effective brightness temperature which can be conveniently measured by a radiometer from remote sensing platforms.
Gupia, S. K., Tiwari, S. N.
core   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Leaf expansion and leaf turnover of perennial C4 grasses growing at moderately low temperatures

open access: yesRevista de la Facultad de Ciencias Agrarias, 2017
Understanding the mechanisms by which some C4 grasses grow more than others at moderately low temperatures (~12-20ºC) is valuable to select materials to lengthen the growing season.
Germán D. Berone
doaj  

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Cardinal temperatures variability within a tropical japonica rice diversity panel

open access: yesPlant Production Science, 2018
Air temperature is one of the most critical climatic factors controlling rice growth, development, and production in current and future climatic scenarii predicting increasingly frequent situations of extreme and/or fluctuating temperatures.
Lauriane Rouan   +5 more
doaj   +1 more source

CONTINUED INVESTIGATION OF AN ADVANCED-TEMPERATURE, TANTALUMMODIFIED, NICKEL-BASE ALLOY [PDF]

open access: yes
Tensile and stress-rupture properties of a tantalum modified nickel-base ...
Freche, J. C., Waters, W. J.
core   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

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