Results 91 to 100 of about 5,804,591 (298)

Mapping of basic density within European aspen stems in Latvia

open access: yesSilva Fennica, 2017
The objective of this study was to investigate basic density and its within-stem variation by studying 84 European aspen stems from 28 forest stands in Latvia.
Liepiņš, Jānis   +4 more
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Caracterização do lenho e variação radial de Pittosporum undulatum Vent. (pau-incenso)

open access: yesHoehnea
Estudou-se o lenho de Pittosporum undulatum do Parque Estadual Alberto Löfgren, objetivando-se sua caracterização, investigar a variação radial da anatomia e densidade básica, suas correlações e discutir os resultados em um contexto ecológico. Empregaram-
Eduardo Luiz Longui   +6 more
doaj   +1 more source

Observations on the effect of age on the basic density of larch wood

open access: yesSilva Fennica, 1978
About 100 years old larch ( Lebed. And Mill.) trees were felled and the basic density samples taken from the stump level were determined. The number of trees was 21 and number of samples 378.
Kärkkäinen, Matti
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

Compression wood in Pinus radiata II: Density and chemical composition Madera de compresión en Pinus radiata II: Densidad y compuestos químicos

open access: yesMaderas: Ciencia y Tecnología, 2009
Ten 22 year old radiata pine trees growing in two stands in Chile, one in clay and the other in humid sand soils showing some lean, were assessed for chemical composition and wood density of compression wood.
J. E Díaz-vaz   +5 more
doaj  

Calculating the basic density of whole tree- and logging residue chips

open access: yesSilva Fennica, 1977
A method is presented in this study for calculating the basic density of whole tree- and logging residue chips and the results of trial measurements on some commonly used chip sorts. The basic density of Scots pine whole tree chips was found to be 1–18
Mäkelä, Markku
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

LogConcDEAD: An R Package for Maximum Likelihood Estimation of a Multivariate Log-Concave Density [PDF]

open access: yes
In this article we introduce the R package LogConcDEAD (Log-concave density estimation in arbitrary dimensions). Its main function is to compute the nonparametric maximum likelihood estimator of a log-concave density.
Madeleine Cule   +2 more
core  

The genetic correlation between air-dried density and basic density in Eucalyptus nitens wood cores

open access: yes, 2008
Cores extracted from trees to assess wood chemistry are generally not used to assess basic density in eucalypt pulpwood breeding programmes, as the measurement of basic density requires high temperature drying.
Raymond, CA (15479075)   +2 more
core   +1 more source

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