Results 91 to 100 of about 6,030,938 (261)
Mapping of basic density within European aspen stems in Latvia
Silva Fennica, 2017 The objective of this study was to investigate basic density and its within-stem variation by studying 84 European aspen stems from 28 forest stands in Latvia.
Liepiņš, Jānis +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Whole-stem wood basic density and growth–density relationships in
Industrial Crops and ProductsRaw-material assessment usually treats wood quantity and density separately and takes whole-tree density from a single breast-height disc. We quantified whole-stem wood basic density and its associations with radial growth and competition under two ...
Xiaoyuan Li, Qingwen Yang, Weiwei Jia
doaj +1 more source
Observations on the effect of age on the basic density of larch wood
Silva Fennica, 1978 About 100 years old larch ( Lebed. And Mill.) trees were felled and the basic density samples taken from the stump level were determined. The number of trees was 21 and number of samples 378.
Kärkkäinen, Matti
doaj +1 more source
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Arbitrary choice of basic variables in density functional theory: Formalism
, 2018 The Hohenberg-Kohn theorem of the density functional theory (DFT) is extended by modifying the Levy constrained-search formulation. The theorem allows us to choose arbitrary physical quantities as basic variables which determine the ground-state ...
Higuchi, M, Higuchi, K
core
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
A Guided Tour Through Modern Charge Density Analysis
, 2011 A concise summary is provided on the basic aspects of charge density (CD) analysis and an overview of the charge density research and developments over the last 10 years. A glimpse is given to the issues which are treated in more details in the remaining
Piero Macchi +3 more
core +1 more source
Molecular Oncology, EarlyView.Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source