Results 191 to 200 of about 148,826 (294)

Genome-Wide Identification and Evolutionary Analysis of the bHLH Transcription Factor Family in Rosa roxburghii. [PDF]

Int J Mol Sci
Li YY, Ling LZ, Zhang SD.
europepmc   +1 more source

A remote surface loop modulates core structure and cold activity in phosphopantetheine adenylyltransferase. [PDF]

PLoS One
Nam Y, Hwang J, Kim B, Lee JH, Do H.
europepmc   +1 more source

Computational modelling of the equine arteritis virus GP5/M Dimer: Implications for immune evasion and virulence. [PDF]

PLoS One
Veit M, Matczuk AK.
europepmc   +1 more source

The Endothelial CXCR Family in Vascular Health and Disease

iNew Medicine, EarlyView.
ABSTRACT Endothelial cells (ECs) form the dynamic interface between blood and tissue, serving as key regulators of vascular homeostasis, inflammation, and repair. Among the molecular systems governing endothelial behavior, the C‐X‐C motif chemokine receptor (CXCR) family—originally characterized in immunology for its roles in leukocyte trafficking and ...
Zhiming Wu, Yandi Wu, Suowen Xu, Yu Huang, Li Wang   +4 more
wiley   +1 more source

<i>ZmbHLH81</i> Enhances Maize Drought Tolerance via Direct Transcriptional Activation of ABA Signaling and ROS Scavenging Genes. [PDF]

Int J Mol Sci
Zhang N, Wang G, Zhang X, Zhao W, Shi Q, Fan X, Lin N, Song S.   +7 more
europepmc   +1 more source

Engineering exosomal cargo loading via endogenous molecular pathways: Strategies to enhance therapeutic potential

Interdisciplinary Medicine, EarlyView.
This review illustrates how scientists engineer exosomes by hijacking the cell's own cargo‐sorting machinery. These strategies efficiently load therapeutic molecules into natural vesicles, creating powerful next‐generation drug delivery systems (Created with BioGDP.com).
Huanrong Zhu, Chenning Zhang, Shihan Ma, Zhanxue Xu, Cailing Liang, Fang Cheng, Hongbo Chen   +6 more
wiley   +1 more source

Cryo-EM structures of UBA6 reveal mechanisms of E1-E2 specificity and dual FAT10/ubiquitin thioester transfer. [PDF]

Nat Commun
Nayak D, Jia L, Dos Santos Bury P, Ruben EA, Shukla A, Nayak A, Stratton CM, Ebadi P, Cho H, Tumanova AA, Varughese JT, Yuan L, Gao F, Cano KE, Davies C, Sung P, Gack MU, Wasmuth EV, Olsen SK.   +18 more
europepmc   +1 more source

Multimodal MRI and multiomics reveal high‐risk neurophenotype in brain‐gut circuits as therapeutic target for Crohn's disease

Interdisciplinary Medicine, EarlyView.
Through a translational framework combining prospective dual‐center clinical cohorts with dextran sulfate sodium‐induced colitis models, this work integrated advanced neuroimaging, multi‐omics and neuromodulation interventions to redefine the high‐risk neurophenotype as a sustained pathogenic driver rather than a mere phenomenon, proposing brain‐gut ...
Xuehua Li, Ruonan Zhang, Xiaodi Shen, Shaochun Lin, Chuhuai Wang, Weikai Zheng, Weimiao Kong, Zihao Lin, Rongchang Li, Caiguang Liu, Xin Cao, Li Huang, Weitao He, Jinjiang Lin, Haijie Wang, Zhoulei Li, Marietta Iacucci, Subrata Ghosh, Zhenpeng Peng, Canhui Sun, Minhu Chen, Guang Yang, Yejun Wang, Ren Mao, Shi‐Ting Feng   +24 more
wiley   +1 more source

Characterization of the Crustacean Methyl Farnesoate Transcriptional Signaling Genes. [PDF]

Int J Mol Sci
Bentley VL, Pérez-Moreno JL, Durica DS, Mykles DL.   +3 more
europepmc   +1 more source

Microelectromechanical system‐based devices for the diagnosis, treatment, and monitoring of ophthalmic diseases

Interdisciplinary Medicine, EarlyView.
Due to the characteristics of miniaturization, high sensing performance, integration, and high comfort, MEMS‐based devices were employed to design sensors, imaging systems, drug delivery systems, retinal prosthesis, surgical tools, and wearable products for the ophthalmic disease diagnosis, treatment, and monitoring.
Yaling Peng, Xiaoming Huang, Xueyuan Zhang, Yiling Jiang, Xin Zhang, Xueying Zeng, Fengyuan Sun, Peng Liu, Jin Zhou, Zewei Luo, Tong Wu   +10 more
wiley   +1 more source