Results 201 to 210 of about 148,826 (294)

Structural and functional insights into TBC1D17 highlight the importance of the previously uncharacterized Rab-binding domain. [PDF]

open access: yesProtein Sci
Nielipińska D   +6 more
europepmc   +1 more source

From regulatory mechanisms to cutting‐edge applications: Research progress of ultrasound, electrical, magnetic, and optical stimulation in neural modulation

open access: yesJournal of Intelligent Medicine, EarlyView.
Abstract In recent years, the clinical treatment and symptom management of neurological disorders have faced significant challenges due to the high complexity of the nervous system's structure and function. Against this backdrop, physical stimulation techniques have emerged as a vital complementary approach to traditional pharmacological treatments and
Wanying Li, Liqun Chen
wiley   +1 more source

Supercritical Angle Fluorescence and Raman Techniques in Biophotonics

open access: yesLaser &Photonics Reviews, EarlyView.
Supercritical angle fluorescence (SAF) microscopy and supercritical angle Raman (SAR) spectroscopy have emerged as powerful tools in the field of biophotonics, enabling high‐resolution imaging and spectroscopy of biological specimens near interfaces. This review article provides a comprehensive overview of the principles, techniques, applications, and ...
Subir Das   +2 more
wiley   +1 more source

Recent Advances (2023–2025) of Capillary Electrophoresis‐Mass Spectrometry (CE‐MS) for Top‐Down Proteomics

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT Top‐down proteomics (TDP) characterizes proteoforms in cells, tissues, and biofluids, in discovery mode and on a global scale, requiring analytical tools with high peak capacity for proteoform separation and high sensitivity for proteoform detection, given the extremely high proteoform complexity and wide proteoform concentration dynamic range.
Guijie Zhu   +5 more
wiley   +1 more source

Testican‐1‐MMP axis in tumour extracellular matrix (ECM) remodelling: interaction dynamics analysis and an in silico perspective

open access: yesThe Journal of Pathology, EarlyView.
Abstract The extracellular matrix (ECM) plays a pivotal role in facilitating tumour development, invasiveness, metastasis, and immunoevasive processes through dynamic ECM remodelling processes. Testican‐1 (SPOCK1), an excretory matricellular proteoglycan, is suggested to exert a role in the facilitation of ECM remodelling processes through interacting ...
Sepideh Youssefi   +6 more
wiley   +1 more source

Ligand binding modes of the bitter taste receptor T2R14 and T2R46. [PDF]

open access: yesNat Struct Mol Biol
Tan Q   +13 more
europepmc   +1 more source

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