Results 91 to 100 of about 106,709 (199)

The subcellular localization of the ChoRE-binding protein, encoded by the Williams-Beuren syndrome critical region gene 14, is regulated by 14-3-3 [PDF]

, 2017
The Williams-Beuren syndrome (WBS) is a contiguous gene syndrome caused by chromosomal rearrangements at chromosome band 7q11.23. Several endocrine phenotypes, in particular impaired glucose tolerance and silent diabetes, have been described for this ...
Antonarakis, Stylianos E., Howald, Cédric, Merla, Giuseppe, Reymond, Alexandre   +3 more
core  

Transcriptome pathways unique to dehydration tolerant relatives of modern wheat [PDF]

, 2009
Among abiotic stressors, drought is a major factor responsible for dramatic yield loss in agriculture. In order to reveal differences in global expression profiles of drought tolerant and sensitive wild emmer wheat genotypes, a previously deployed shock ...
AN Olsen, B Barnabas, B Vinocur, C Guy, D Bartels, DB Lobell, E Ormeno, EA Bray, G Toledo-Ortiz, GP Xue, GR Cramer, Hans J. Bohnert, HG Jones, Hikmet Budak, HJ Bohnert, IK Vasil, J Dubcovsky, J Zhou, JL Araus, Jyothi Thimmapuram, K Deuschle, K Higuchi, K Higuchi, K Poustini, K Shinozaki, L Cseke, L Rodriguez-Uribe, L Xiong, M Mohammadi, M Seki, MB Eisen, N Kaur, NC Collins, Neslihan Z. Ergen, O Cebeci, P Langridge, P Rampino, PBK Kishor, PY Muller, R Kaldenhoff, R Munns, S Chao, S Mahajan, S Ramanjulu, T Eulgem, The Gene Ontology Consortium, V Talame, W Li, W Wang, YG Shen, YH Lee, ZN Ergen, ZN Ergen, ZN Ozturk   +53 more
core   +1 more source

Role of differentiated embryo-chondrocyte expressed gene 2 in immunity

Frontiers in Immunology
Differentiated embryo-chondrocyte expressed gene 2 (DEC2) is a member of the basic helix-loop-helix (bHLH) subfamily of transcription factors. DEC2 is implicated in tumor immunotherapy, immune system function regulation, and autoimmune diseases.
Yujing Li, Yujing Li, Yinan Ma, Yinan Ma, Yang Liu, Na Tang, Na Tang, Wenzhu Zhang, Wenzhu Zhang, Jingru Huo, Jingru Huo, Di Zhang, Di Zhang   +12 more
doaj   +1 more source

Genome-Wide Identification and Characterization of the bHLH Transcription Factor Family in Pepper (Capsicum annuum L.)

Frontiers in Genetics, 2020
Plant basic helix–loop–helix (bHLH) transcription factors are involved in the regulation of various biological processes in plant growth, development, and stress response.
Zhishuo Zhang, Zhishuo Zhang, Juan Chen, Chengliang Liang, Feng Liu, Xilin Hou, Xuexiao Zou, Xuexiao Zou, Xuexiao Zou   +8 more
doaj   +1 more source

Induction and repression of mammalian achaete-scute homologue (MASH) gene expression during neuronal differentiation of P19 embryonal carcinoma cells [PDF]

, 1992
MASH1 and MASH2, mammalian homologues of the Drosophila neural determination genes achaete-scute, are members of the basic helix-loop-helix (bHLH) family of transcription factors.
Anderson, David J., Johnson, Jane E., Saito, Tetsuichiro, Zimmerman, Kathryn   +3 more
core  

Elevated expression of human bHLH factor ATOH7 accelerates cell cycle progression of progenitors and enhances production of avian retinal ganglion cells. [PDF]

, 2018
The production of vertebrate retinal projection neurons, retinal ganglion cells (RGCs), is regulated by cell-intrinsic determinants and cell-to-cell signaling events.
Hashimoto, Takao, Tang, Ronald, Yang, Xian-Jie, Zhang, Xiang-Mei   +3 more
core   +1 more source

Regulation of protein function by interfering protein species

Biomolecular Concepts, 2012
Most proteins do not function alone but act in protein complexes. For several transcriptional regulators, it is known that they have to homo- or heterodimerize prior to DNA binding.
Graeff Moritz, Wenkel Stephan
doaj   +1 more source

NPAS1-ARNT and NPAS3-ARNT crystal structures implicate the bHLH-PAS family as multi-ligand binding transcription factors

eLife, 2016
The neuronal PAS domain proteins NPAS1 and NPAS3 are members of the basic helix-loop-helix-PER-ARNT-SIM (bHLH-PAS) family, and their genetic deficiencies are linked to a variety of human psychiatric disorders including schizophrenia, autism spectrum ...
Dalei Wu, Xiaoyu Su, Nalini Potluri, Youngchang Kim, Fraydoon Rastinejad   +4 more
doaj   +1 more source

Identification of transcription factor binding sites in promoter databases [PDF]

, 2011
Transcription factors (TFs) are the proteins which regulates the expression of their target genes either in a positive or negative manner. TFs realize this task by binding to a specific DNA sequence contained in promoter regions, via their DNA binding ...
Dağ, Uğur, Durası, İlknur Melis, Erdoğan, Burcu, Güngör, Burcu Bakır, Kurnaz, Işıl Aksan, Sezerman, Uğur   +5 more
core   +1 more source

Prognostic Significance of the Lymphoblastic Leukemia-Derived Sequence 1 (LYL1) Gene Expression in Egyptian Patients with Acute Myeloid Leukemia

Turkish Journal of Hematology, 2014
OBJECTIVE: Aberrant activation of transcription factor genes is the most frequent target of genetic alteration in lymphoid malignancies. The lymphoblastic leukemia-derived sequence 1 (LYL1) gene, which encodes a basic helix-loop helix, was first ...
Nadia El Menshawy, Doaa Shahin, Hayam Fathi Ghazi   +2 more
doaj   +1 more source