Homodimeric and Heterodimeric Interactions among Vertebrate Basic Helix-Loop-Helix Transcription Factors. [PDF]
Int J Mol Sci, 2021 The basic helix–loop–helix transcription factor (bHLH TF) family is involved in tissue development, cell differentiation, and disease. These factors have transcriptionally positive, negative, and inactive functions by combining dimeric interactions among family members.
Torres-Machorro AL.
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Basic helix-loop-helix transcription factors and enteroendocrine cell differentiation. [PDF]
Diabetes Obes Metab, 2011 For over 30 years it has been known that enteroendocrine cells derive from common precursor cells in the intestinal crypts. Until recently little was understood about the events that result in commitment to endocrine differentiation or the eventual segregation of over 10 different hormone‐expressing cell types in the gastrointestinal tract ...
Li HJ +4 more
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Promoterless Luciferase Reporter Gene Is Transactivated by Basic Helix-Loop-Helix Transcription Factors [PDF]
BioTechniques, 2002 Seok Jong Hong, Han Chae, Kwang-Soo Kim
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Basic helix-loop-helix transcription factors and regulation of alkaloid biosynthesis. [PDF]
Plant Signal Behav, 2011 Transcription factors of the basic Helix-Loop-Helix (bHLH) family play a central role in cell proliferation, determination, and differentiation. In plants, the regulatory functions of bHLHs in phenylpropanoid biosynthesis have been well established with regard to other interacting-proteins; i.e., MYB and WD40 repeat proteins.
Yamada Y, Koyama T, Sato F.
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Recognizing the Basics of Phytochrome-Interacting Factors in Plants for Abiotic Stress Tolerance
Plant Stress, 2022 Phytochrome-interacting factor (PIF) belongs to the basic helix-ring-helix (Basic Helix– Loop– Helix, bHLH) type transcription factors, which are involved in multiple biological processes in plants as a ''hub'' of intracellular signal regulation, PIF not
Shah Saud +7 more
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The Arabidopsis Basic/Helix-Loop-Helix Transcription Factor Family[W] [PDF]
The Plant Cell, 2003 AbstractThe basic/helix-loop-helix (bHLH) proteins are a superfamily of transcription factors that bind as dimers to specific DNA target sites and that have been well characterized in nonplant eukaryotes as important regulatory components in diverse biological processes.
Toledo-Ortiz, Gabriela +2 more
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The basic helix–loop–helix transcription factor capsulin controls spleen organogenesis [PDF]
Proceedings of the National Academy of Sciences, 2000 Formation of numerous internal organs involves reciprocal epithelial–mesenchymal signaling and subsequent patterning and growth of the organ primordium. Capsulin is a basic helix–loop–helix transcription factor expressed in mesenchymal cells that encapsulate the epithelial primordia of internal organs, including the kidney and lung, as ...
J, Lu +5 more
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Overexpression of HLH4 Inhibits Cell Elongation and Anthocyanin Biosynthesis in Arabidopsis thaliana
Cells, 2022 In plants, many basic helix-loop-helix (bHLH) transcription factors are involved in controlling cell elongation. Three bHLH proteins, PACLOBTRAZOL RESISTANCE1 (PRE1), Cryptochrome Interacting Basic Helix-loop-helix 5 (CIB5), and Arabidopsis ILI1 binding ...
Quancan Hou +11 more
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Scientific African, 2022 Id proteins (1–4) which are dominant-negative antagonists of the basic helix-loop-helix (bHLH) family of transcription factors function in a variety of cellular processes.
Foster Kyei
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Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature [PDF]
Differentiation, 2010 A phylogenetic analysis of the basic helix-loop-helix (bHLH) gene superfamily was performed using seven different species (human, mouse, rat, worm, fly, yeast, and plant Arabidopsis) and involving over 600 bHLH genes (Stevens et al., 2008). All bHLH genes were identified in the genomes of the various species, including expressed sequence tags, and the ...
Skinner, Michael K +3 more
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