Results 31 to 40 of about 106,709 (199)

The T-cell oncogene Tal2 is a Target of PU.1 and upregulated during osteoclastogenesis [PDF]

open access: yes, 2013
Transcription factors play a crucial role in regulating differentiation processes during human life and are important in disease. The basic helix-loop-helix transcription factors Tal1 and Lyl1 play a major role in the regulation of gene expression in the
Courtial, Nadine   +5 more
core   +2 more sources

The bHLH transcription factor AhbHLH112 improves the drought tolerance of peanut

open access: yesBMC Plant Biology, 2021
Background Basic helix-loop-helix (bHLH) transcription factors (TFs) are one of the largest gene families in plants. They regulate gene expression through interactions with specific motifs in target genes.
Chunjuan Li   +7 more
doaj   +1 more source

Launching the T-cell-lineage developmental programme [PDF]

open access: yes, 2008
Multipotent blood progenitor cells enter the thymus and begin a protracted differentiation process in which they gradually acquire T-cell characteristics while shedding their legacy of developmental plasticity. Notch signalling and basic helix-loop-helix
Moore, Jonathan E.   +2 more
core   +1 more source

The Role of Neurod Genes in Brain Development, Function, and Disease

open access: yesFrontiers in Molecular Neuroscience, 2021
Transcriptional regulation is essential for the correct functioning of cells during development and in postnatal life. The basic Helix-loop-Helix (bHLH) superfamily of transcription factors is well conserved throughout evolution and plays critical roles ...
Svetlana Tutukova   +4 more
doaj   +1 more source

BMP and FGF signaling interact to pattern mesoderm by controlling basic helix-loop-helix transcription factor activity

open access: yeseLife, 2018
The mesodermal germ layer is patterned into mediolateral subtypes by signaling factors including BMP and FGF. How these pathways are integrated to induce specific mediolateral cell fates is not well understood.
Richard H Row   +7 more
doaj   +1 more source

Differential Interactions of Id Proteins with Basic-Helix-Loop-Helix Transcription Factors [PDF]

open access: yesJournal of Biological Chemistry, 1997
Dimerization of three Id proteins (Id1, Id2, and Id3) with the four class A E proteins (E12, E47, E2-2, and HEB) and two groups of class B proteins, the myogenic regulatory factors (MRFs: MyoD, myogenin, Myf-5 and MRF4/Myf-6), and the hematopoietic factors (Scl/Tal-1, Tal-2, and Lyl-1) were tested in a quantitative yeast 2-hybrid assay.
K, Langlands   +3 more
openaire   +2 more sources

Genomic survey of TCP transcription factors in plants: Phylogenomics, evolution and their biology

open access: yesFrontiers in Genetics, 2022
The TEOSINTE BRANCHED1 (TBI1), CYCLOIDEA (CYC), and PROLIFERATING CELL NUCLEAR ANTIGEN FACTORS (PCF1 and PCF2) proteins truncated as TCP transcription factors carry conserved basic-helix-loop-helix (bHLH) structure, related to DNA binding functions ...
Haiying Zhou   +5 more
doaj   +1 more source

Dial M(RF) for myogenesis [PDF]

open access: yes, 2013
The transcriptional regulatory network that controls the determination and differentiation of skeletal muscle cells in the embryo has at its core the four myogenic regulatory factors (MRFs) Myf5, MyoD, Mrf4 and MyoG.
Carvajal, Jaime J.   +2 more
core   +1 more source

High-throughput sequencing of highbush blueberry transcriptome and analysis of basic helix-loop-helix transcription factors

open access: yesJournal of Integrative Agriculture, 2017
The highbush blueberry (Vaccinium corymbosum) Duke, was used to construct a de novo transcriptome sequence library and to perform data statistical analysis. Mega 4, CLC Sequence Viewer 6 software, and quantitative PCR were employed for bioinformatics and
Yang SONG   +7 more
doaj   +1 more source

The divergence between T cell and innate lymphoid cell fates controlled by E and Id proteins

open access: yesFrontiers in Immunology, 2022
T cells develop in the thymus from lymphoid primed multipotent progenitors or common lymphoid progenitors into αβ and γδ subsets. The basic helix-loop-helix transcription factors, E proteins, play pivotal roles at multiple stages from T cell commitment ...
Aneta Pankow   +4 more
doaj   +1 more source

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