Results 41 to 50 of about 106,709 (199)

The basic helix loop helix transcription factor twist1 is a novel regulator of ATF4 in osteoblasts [PDF]

open access: yes, 2012
Parathyroid hormone (PTH) is an essential regulator of endochondral bone formation and an important anabolic agent for the reversal of bone loss. PTH mediates its functions in part by regulating binding of the bone‐related activating transcription factor
Ardura   +41 more
core   +1 more source

Multi-omic profiling of pituitary thyrotropic cells and progenitors

open access: yesBMC Biology, 2021
Background The pituitary gland is a neuroendocrine organ containing diverse cell types specialized in secreting hormones that regulate physiology.
Alexandre Z. Daly   +5 more
doaj   +1 more source

Fluorescence Resonance Energy Transfer (FRET) as a method to calculate the dimerization strength of basic Helix-Loop-Helix (bHLH) proteins

open access: yesBiological Procedures Online, 2004
Post-translational modifications such as phosphorylation play a vital role in the regulation of protein function. In our study of the basic Helix-loop-Helix (bHLH) transcription factor HAND1, we show that HAND1 is phosphorylated during the trophoblast ...
Centonze Victoria E.   +2 more
doaj   +1 more source

Srebf1 Controls Midbrain Dopaminergic Neurogenesis

open access: yesCell Reports, 2020
Summary: Liver X receptors (LXRs) and their ligands are potent regulators of midbrain dopaminergic (mDA) neurogenesis and differentiation. However, the molecular mechanisms by which LXRs control these functions remain to be elucidated. Here, we perform a
Enrique M. Toledo   +11 more
doaj   +1 more source

Generalized, switch-like competitive heterodimerization networks [PDF]

open access: yes, 2007
High-dimensional switches have been proposed as a way to model cellular differentiation, particularly in the context of basic Helix-Loop-Helix (bHLH) competitive heterodimerization networks.
Cinquin, O, Page, KM
core   +1 more source

The basic helix-loop-helix transcription factor, dHAND, is required for vascular development [PDF]

open access: yesJournal of Clinical Investigation, 2000
Reciprocal interactions between vascular endothelial cells and vascular mesenchymal cells are essential for angiogenesis. Here we show that the basic helix-loop-helix transcription factor, dHAND/Hand2, is expressed in the developing vascular mesenchyme and its derivative, vascular smooth muscle cells (VSMCs). Targeted deletion of the dHAND gene in mice
H, Yamagishi, E N, Olson, D, Srivastava
openaire   +2 more sources

Pleurotus ostreatus bHLH transcription factors regulate plant growth and development when expressed in Arabidopsis

open access: yesJournal of Plant Interactions, 2017
Fungi interact with plants in different ways in nature; however, it remains largely unclear if fungus gene may affect plant growth and development. Basic helix-loop-helix (bHLH) transcription factors are found in almost all organisms including plants and
Siyu Chen   +6 more
doaj   +1 more source

Generation of the iPSC line CUIMCi003-A derived from a patient with severe early onset obesity

open access: yesStem Cell Research, 2021
Aryl hydrocarbon receptor nuclear translocator 2 (ARNT2) is a basic helix-loop-helix (bHLH/PAS) transcription factor involved in the development of paraventricular nucleus of the hypothalamus (PVH) through the heterodimerization with Single-minded 1 ...
Grazia Iannello   +4 more
doaj   +1 more source

Redox modulation of plant developmental regulators from the class I TCP transcription factor family [PDF]

open access: yes, 2013
TEOSINTE BRANCHED1-CYCLOIDEA-PROLIFERATING CELL FACTOR1 (TCP) transcription factors participate in plant developmental processes associated with cell proliferation and growth.
Gonzalez, Daniel Hector   +2 more
core   +1 more source

Genome-wide analysis of bHLH and bZIP Transcription factors and their temporal expression under abiotic stress conditions in Groundnut (Arachis hypogaea L.) [PDF]

open access: yesJournal of Stress Physiology & Biochemistry, 2022
Groundnut (Arachis hypogaea L.), is an important subsistence oil yielding crop of the semi-arid tropics and often exposed to several environmental cues (high temperature, drought & heavy metal).
Suchithra B   +2 more
doaj  

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