The basic helix loop helix transcription factor twist1 is a novel regulator of ATF4 in osteoblasts [PDF]
Parathyroid hormone (PTH) is an essential regulator of endochondral bone formation and an important anabolic agent for the reversal of bone loss. PTH mediates its functions in part by regulating binding of the bone‐related activating transcription factor
Ardura +41 more
core +1 more source
Multi-omic profiling of pituitary thyrotropic cells and progenitors
Background The pituitary gland is a neuroendocrine organ containing diverse cell types specialized in secreting hormones that regulate physiology.
Alexandre Z. Daly +5 more
doaj +1 more source
Post-translational modifications such as phosphorylation play a vital role in the regulation of protein function. In our study of the basic Helix-loop-Helix (bHLH) transcription factor HAND1, we show that HAND1 is phosphorylated during the trophoblast ...
Centonze Victoria E. +2 more
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Srebf1 Controls Midbrain Dopaminergic Neurogenesis
Summary: Liver X receptors (LXRs) and their ligands are potent regulators of midbrain dopaminergic (mDA) neurogenesis and differentiation. However, the molecular mechanisms by which LXRs control these functions remain to be elucidated. Here, we perform a
Enrique M. Toledo +11 more
doaj +1 more source
Generalized, switch-like competitive heterodimerization networks [PDF]
High-dimensional switches have been proposed as a way to model cellular differentiation, particularly in the context of basic Helix-Loop-Helix (bHLH) competitive heterodimerization networks.
Cinquin, O, Page, KM
core +1 more source
The basic helix-loop-helix transcription factor, dHAND, is required for vascular development [PDF]
Reciprocal interactions between vascular endothelial cells and vascular mesenchymal cells are essential for angiogenesis. Here we show that the basic helix-loop-helix transcription factor, dHAND/Hand2, is expressed in the developing vascular mesenchyme and its derivative, vascular smooth muscle cells (VSMCs). Targeted deletion of the dHAND gene in mice
H, Yamagishi, E N, Olson, D, Srivastava
openaire +2 more sources
Fungi interact with plants in different ways in nature; however, it remains largely unclear if fungus gene may affect plant growth and development. Basic helix-loop-helix (bHLH) transcription factors are found in almost all organisms including plants and
Siyu Chen +6 more
doaj +1 more source
Generation of the iPSC line CUIMCi003-A derived from a patient with severe early onset obesity
Aryl hydrocarbon receptor nuclear translocator 2 (ARNT2) is a basic helix-loop-helix (bHLH/PAS) transcription factor involved in the development of paraventricular nucleus of the hypothalamus (PVH) through the heterodimerization with Single-minded 1 ...
Grazia Iannello +4 more
doaj +1 more source
Redox modulation of plant developmental regulators from the class I TCP transcription factor family [PDF]
TEOSINTE BRANCHED1-CYCLOIDEA-PROLIFERATING CELL FACTOR1 (TCP) transcription factors participate in plant developmental processes associated with cell proliferation and growth.
Gonzalez, Daniel Hector +2 more
core +1 more source
Genome-wide analysis of bHLH and bZIP Transcription factors and their temporal expression under abiotic stress conditions in Groundnut (Arachis hypogaea L.) [PDF]
Groundnut (Arachis hypogaea L.), is an important subsistence oil yielding crop of the semi-arid tropics and often exposed to several environmental cues (high temperature, drought & heavy metal).
Suchithra B +2 more
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