Results 61 to 70 of about 106,709 (199)
Regulatory module network of basic/helix-loop-helix transcription factors in mouse brain [PDF]
Genome Biology, 2007 Abstract Background The basic/helix-loop-helix (bHLH) proteins are important components of the transcriptional regulatory network, controlling a variety of biological processes, especially the development of the central nervous system.
Li, Jing +8 more
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EMBO Molecular Medicine, 2014 MYC family oncoproteins (MYC, N‐MYC and L‐MYC) function as basic helix‐loop‐helix‐leucine zipper (bHLH‐Zip) transcription factors that are activated (i.e., overexpressed) in well over half of all human malignancies (Boxer & Dang, 2001; Beroukhim et al ...
Franz X Schaub, John L Cleveland
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Scientific Reports, 2021 As one of the largest transcription factor family, basic helix-loop-helix (bHLH) transcription factor family plays an important role in plant metabolism, physiology and growth.
Ming Li +9 more
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Transcription factors in microcephaly
Frontiers in Neuroscience, 2023 Higher cognition in humans, compared to other primates, is often attributed to an increased brain size, especially forebrain cortical surface area. Brain size is determined through highly orchestrated developmental processes, including neural stem cell ...
Youngshin Lim, Youngshin Lim
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Basic helix-loop-helix proteins E2A and HEB induce immature T-cell receptor rearrangements in nonlymphoid cells [PDF]
, 2001 T-cell receptor (TCR) gene rearrangements are mediated via V(D)J recombination, which is strictly regulated during lymphoid differentiation, most probably through the action of specific transcription factors.
Dongen, J.J.M. (Jacques) van +4 more
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Atoh8 in Development and Disease
Biology, 2022 Atoh8 belongs to a large superfamily of transcriptional regulators called basic helix-loop-helix (bHLH) proteins. bHLH proteins have been identified in a wide range of organisms from yeast to humans.
Satya Srirama Karthik Divvela +2 more
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Frontiers in Plant Science, 2021 Basic helix-loop-helix proteins (bHLHs) comprise one of the largest families of transcription factors in plants. They have been shown to be involved in responses to various abiotic stresses, such as drought, salinity, chilling, heavy metal toxicity, iron
Yuchen Qian +6 more
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Geminin regulates the transcriptional and epigenetic status of neuronal fate-promoting genes during mammalian neurogenesis [PDF]
, 2012 Regulating the transition from lineage-restricted progenitors to terminally differentiated cells is a central aspect of nervous system development. Here, we investigated the role of the nucleoprotein geminin in regulating neurogenesis at a mechanistic ...
Kroll, Kristen L +5 more
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Expression of neurogenin3 reveals an islet cell precursor population in the pancreas [PDF]
, 2000 Differentiation of early gut endoderm cells into the endocrine cells forming the pancreatic islets of Langerhans depends on a cascade of gene activation events controlled by transcription factors including the basic helix-loop-helix (bHLH) proteins.
Anderson, David J. +8 more
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Identification of dividing, determined sensory neuron precursors in the mammalian neural crest [PDF]
, 1999 Sensory and autonomic neurons of the vertebrate peripheral nervous system are derived from the neural crest. Here we use the expression of lineage-specific transcription factors as a means to identify neuronal subtypes that develop in rat neural crest ...
Anderson, David J. +2 more
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