Results 81 to 90 of about 106,709 (199)

Identification of Melatonin-Regulated Genes in the Ovine Pituitary Pars Tuberalis, a Target Site for Seasonal Hormone Control [PDF]

, 2008
The pars tuberalis (PT) of the pituitary gland expresses a high density of melatonin (MEL) receptors and is believed to regulate seasonal physiology by decoding changes in nocturnal melatonin secretion.
Alison Downing, Ando, Andrew S. I. Loudon, Ashburner, Bae, Barrett, Bartness, Bechtold, Benoit Malpaux, Bockers, Bockers, Bockmann, Brahimi-Horn, Camon, Carr, Chemineau, Chen, Curlewis, Daphne Mouzaki, Dardente, Dave W. Burt, David Waddington, Draghici, Dupre, Fukuhara, Gerald A. Lincoln, Ghorbel, Graham, Grossmann, Hanon, Hazlerigg, Hazlerigg, Hazlerigg, Hogenesch, Hu, Hu, Johnston, Johnston, Johnston, Julian R. E. Davis, Kel, Kijas, Klosen, Ko, Lamolet, Lee, Lincoln, Lincoln, Lincoln, Lincoln, Malpaux, Merks, Messager, Michan, Morgan, Morgan, Mutoh, Nakao, Naya, Naya, Nilaweera, Oki, Poulin, Reick, Revollo, Richard Talbot, Roepke, Rutter, Samal, Sandrine M. Dupré, Schroeder, Segawa, Stehle, Stirland, Storey, Su, Tobler, Tournier, Wagner, Westfall, Williams, Wittkowski, Yang, Yokoyama   +83 more
core   +2 more sources

The basic helix-loop-helix transcription factor Mist1 functions as a transcriptional repressor of MyoD [PDF]

The EMBO Journal, 1998
A good model system to examine aspects of positive and negative transcriptional regulation is the muscle-specific regulatory factor, MyoD, which is a basic helix-loop-helix (bHLH) transcription factor. Although MyoD has the ability to induce skeletal muscle terminal differentiation in a variety of non-muscle cell types, MyoD activity itself is highly ...
Lemercier, Claudie, To, Robert Q., Carrasco, Rosa A., Konieczny, Stephen F.   +3 more
openaire   +2 more sources

Reciprocal regulation of the basic helix-loop-helix/Per-Arnt-Sim partner proteins, Arnt and Arnt2, during neuronal differentiation [PDF]

, 2013
Basic helix–loop–helix/Per–Arnt–Sim (bHLH/PAS) transcription factors function broadly in development, homeostasis and stress response. Active bHLH/PAS heterodimers consist of a ubiquitous signal-regulated subunit (e.g., hypoxia-inducible factors, HIF-1α ...
Aitola, Antonsson, Azuara, Belsham, Bernstein, Chong, Clark, Daniel J. Peet, Dougherty, Drutel, Freeburg, Furness, Golling, Hankinson, Hao, Hao, Hatada, Hill, Hirose, Hoesel, Hosoya, Huang, Iyer, Jain, Jones-Villeneuve, Kawajiri, Keith, Kewley, Kim, Kozak, Latchney, Maltepe, Maltepe, Martinez, McBurney, McIntosh, Michaud, Michaud, Mikkelsen, Murray L. Whitelaw, Nan Hao, Ooe, Ooe, Ryan, Schoenherr, Sekine, Sogawa, Valouev, Veronica L. D. Bhakti, Wang, Woods, Yamakuchi, Ying   +52 more
core   +1 more source

Basic‐helix‐loop‐helix (bHLH) transcription factor DEC2 negatively regulates vascular endothelial growth factor expression [PDF]

Genes to Cells, 2008
DEC1 (BHLHB2/Sharp2/Stra13) and DEC2 (BHLHB3/Sharp1) are basic‐helix‐loop‐helix (bHLH) transcription factors, involved in cellular differentiation, responses to hypoxia and circadian rhythms. We recently showed that the expression of DEC1 and DEC2 was up‐regulated by hypoxia; however, the functions of these two factors under hypoxic conditions have not
Fuyuki, Sato, Ujjal Kumar, Bhawal, Takeshi, Kawamoto, Katsumi, Fujimoto, Tadaatsu, Imaizumi, Tadanobu, Imanaka, Jun, Kondo, Satoru, Koyanagi, Mitsuhide, Noshiro, Hidemi, Yoshida, Tomomi, Kusumi, Yukio, Kato, Hiroshi, Kijima   +12 more
openaire   +2 more sources

Type I bHLH Proteins Daughterless and Tcf4 Restrict Neurite Branching and Synapse Formation by Repressing Neurexin in Postmitotic Neurons

Cell Reports, 2016
Proneural proteins of the class I/II basic-helix-loop-helix (bHLH) family are highly conserved transcription factors. Class I bHLH proteins are expressed in a broad number of tissues during development, whereas class II bHLH protein expression is more ...
Mitchell D’Rozario, Ting Zhang, Edward A. Waddell, Yonggang Zhang, Cem Sahin, Michal Sharoni, Tina Hu, Mohammad Nayal, Kaveesh Kutty, Faith Liebl, Wenhui Hu, Daniel R. Marenda   +11 more
doaj   +1 more source

Mechanism underlying synergic activation of Tyrosinase promoter by MITF and IRF4 [PDF]

, 2017
Background: The transcription factor interferon regulatory factor 4 (IRF4) was identified to be involved in human pigmentation by genome-wide association studies (GWASs).
Cai, Xinzhang, Chen, Hongsheng, Feng, Yong, He, Chufeng, Li, Jiada, Liu, Huadie, Liu, Xueming, Liu, Yalan, Mei, Lingyun, Peng, Zhen, Song, Jian, Vleminckx, Kris   +11 more
core   +1 more source

The molecular basis of T cell acute lymphoblastic leukemia [PDF]

, 2012
T cell acute lymphoblastic leukemias (T-ALLs) arise from the malignant transformation of hematopoietic progenitors primed toward T cell development, as result of a multistep oncogenic process involving constitutive activation of NOTCH signaling and ...
Adolfo Ferrando, Bash, Bash, Chen, Condorelli, Dube, Fisch, Hagemeijer, Hebert, Ho, Kelliher, Kikuchi, Larson, Lu, McGuire, McGuire, Nagel, Ntziachristos, Ntziachristos, Ono, Pieter Van Vlierberghe, Royer-Pokora, Rubnitz, van Grotel   +23 more
core   +1 more source

Nhlh2 [PDF]

Exercise and Sport Sciences Reviews, 2008
In mice, targeted deletion of the basic helix-loop-helix transcription factor, nescient helix-loop-helix 2 (Nhlh2), leads to adult-onset obesity and reduced physical activity. We propose the novel hypothesis that transcriptional activity by Nhlh2 (NHLH2 in humans) controls either the ability or the motivation for exercise.
Deborah J, Good, Christopher A, Coyle, Dana L, Fox   +2 more
openaire   +2 more sources

Crystal Structure of Tetrameric Arabidopsis MYC2 Reveals the Mechanism of Enhanced Interaction with DNA

Cell Reports, 2017
Jasmonates (JAs) are essential plant hormones that play important roles in the regulation of plant growth and the response to environmental stress. In the JA signaling pathway, the core transcription factors are a class of basic helix-loop-helix (bHLH ...
Teng-fei Lian, Yong-ping Xu, Lan-fen Li, Xiao-Dong Su   +3 more
doaj   +1 more source

MADS-Box and bHLH Transcription Factors Coordinate Transmitting Tract Development in Arabidopsis thaliana

Frontiers in Plant Science, 2020
The MADS-domain transcription factor SEEDSTICK (STK) controls several aspects of plant reproduction. STK is co-expressed with CESTA (CES), a basic Helix-Loop-Helix (bHLH) transcription factor-encoding gene.
Maurizio Di Marzo, Irma Roig-Villanova, Eva Zanchetti, Francesca Caselli, Veronica Gregis, Paola Bardetti, Matteo Chiara, Andrea Guazzotti, Elisabetta Caporali, Marta Adelina Mendes, Lucia Colombo, Martin M. Kater   +11 more
doaj   +1 more source