Results 61 to 70 of about 5,265 (203)

Cellular Stress, Inflammation and Barrier Damage in Gut Epithelial Cells Caused by Aspartame

Allergy, Volume 81, Issue 3, Page 884-901, March 2026.
This study shows that aspartame, at dietary‐relevant doses, induces cytotoxicity, cellular distress associated with endoplasmic reticulum stress, oxidative stress, DNA replication and repair mechanism disturbance culminating in epithelial barrier damage.
Yagiz Pat, Duygu Yazici, Can Zeyneloglu, Huseyn Babayev, Sena Ardicli, Asuncion Garci‐Sanchez, Xiangting Bu, Anja Heider, Oliva Giannelli Viscardi, Lihong Chang, Sheri Simmons, Anthony Almada, Christine Avena, Tye Jensen, Raja Dhir, Ismail Ogulur, Cezmi A. Akdis   +16 more
wiley   +1 more source

Do temporary changes in earnings caused by mean reversion affect firms’ refinancing decisions?

Journal of Financial Research, Volume 49, Issue 1, Page 228-252, Spring 2026.
Abstract We develop a dynamic two‐stage trade‐off model with refinancing when earnings are mean reverting. Our model predicts a negative relation between profitability and leverage at refinancing due to conservative debt increases. With multiple rounds of refinancing, the leverage–profitability relation may turn positive when firms have substantial ...
Elettra Agliardi, Marios Charalambides, Md Shahedur R. Chowdhury, Nicos Koussis   +3 more
wiley   +1 more source

Orthogonal Basic Hypergeometric Laurent Polynomials

Symmetry, Integrability and Geometry: Methods and Applications, 2012
The Askey-Wilson polynomials are orthogonal polynomials in$x = cos heta$, which are given as a terminating $_4phi_3$ basic hypergeometric series. The non-symmetric Askey-Wilson polynomials are Laurent polynomials in $z=e^{iheta}$, which are given as a ...
Mourad E.H. Ismail, Dennis Stanton
doaj   +1 more source

Count Random Variables

Encyclopedia
The observation of randomness patterns serves as guidance for the craft of probabilistic modelling. The most used count models—Binomial, Poisson, Negative Binomial—are the discrete Morris’ natural exponential families whose variance is at most quadratic ...
Sandra Mendonça, António Alberto Oliveira, Dinis Pestana, Maria Luísa Rocha   +3 more
doaj   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, Volume 20, Issue 2, Page 428-446, February 2026.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, Volume 20, Issue 2, Page 260-281, February 2026.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Phase‐Separation of YAP Mediates AJUBA Super Enhancer Activation to Promote Aberrant Mitosis in Breast Cancer

Advanced Science, Volume 13, Issue 8, 9 February 2026.
YAP undergoes phase separation to activate the AJUBA super‐enhancer, driving aberrant mitosis through spindle checkpoint dysregulation in breast cancer. This study uncovers a mechanistic link between YAP condensates, super‐enhancer activation, and aneuploidy formation.
Rui Zhang, Qingwen Huang, Zhuo Chen, Weijian Meng, Hongliang Dong, Zhihong Qi, Liang Liu, Jie Shen, Daxing Xie   +8 more
wiley   +1 more source

Two Inequalities for and Applications

Journal of Inequalities and Applications, 2008
We use the -binomial formula to establish two inequalities for the basic hypergeometric series . As applications of the inequalities, we discuss the convergence of -series.
Wang Mingjin
doaj  

Factorization of Basic Hypergeometric Series

Symmetry, Integrability and Geometry: Methods and Applications
The general problem of the factorization of a basic hypergeometric series is presented and discussed. The case of the general $_2\psi_2$ series is examined in detail. Connections are found with the theory of basic hypergeometric series on root systems. Alternative proofs of several well-known summation and transformation formulae, including Gustafson's
openaire   +2 more sources

On Convergence of -Series Involving Basic Hypergeometric Series

Journal of Inequalities and Applications, 2009
We use inequality technique and the terminating case of the -binomial formula to give some results on convergence of -series involving basic hypergeometric series.
Zhao Xilai, Wang Mingjin
doaj