Results 61 to 70 of about 123,197 (246)

Insights into Clustering Patterns in Romania’s 2020–2024 Measles Cases

Epidemiologia
Background and objectives: During an outbreak, measles cases tend to aggregate into increasingly bigger clusters that show specific characteristics, different from the non-cluster cases.
Valerian-Ionuț Stoian, Cătălin Pleșea-Condratovici, Mădălina Nicoleta Matei, Iulia Draghiev, Liliana Baroiu, Carmina Mușat, Mihaela Patriciu, Valerii Luțenco, Mariana Daniela Ignat, Mihaela Debita   +9 more
doaj   +1 more source

Mathematical model for the control of measles

Journal of Applied Sciences and Environmental Management, 2018
We proposed a mathematical model of measles disease dynamics with vaccination by considering the total number of recovered individuals either from natural recovery or recovery due to vaccination.
O.J. Peter, O.A. Afolabi, A.A. Victor, C.E. Akpan, F.A. Oguntolu   +4 more
doaj   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

The Basic Reproductive Number for Disease Systems with Multiple Coupled Heterogeneities [PDF]

Mathematical Biosciences, 2017
AbstractIn mathematical epidemiology, a well-known formula describes the impact of heterogeneity on the basic reproductive number,R0, for situations in which transmission is separable and for which there is one source of variation in susceptibility and one source of variation in infectiousness.
Lloyd, Alun L., Kitron, Uriel, Perkins, T. Alex, Vazquez-Prokopec, Gonzalo M., Waller, Lance A.   +4 more
openaire   +3 more sources

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Basic reproduction number of SEIRS model on regular lattice

Mathematical Biosciences and Engineering, 2019
In this paper we give a basic reproduction number $\mathscr{R}_0$ of an SEIRS model on regular lattice using next-generation matrix approach. Our result is straightforward but differs from the basic reproduction numbers for various fundamental epidemic models on the regular lattice which have been shown so far.
openaire   +3 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Positive Periodic Solutions of an Epidemic Model with Seasonality

The Scientific World Journal, 2013
An SEI autonomous model with logistic growth rate and its corresponding nonautonomous model are investigated. For the autonomous case, we give the attractive regions of equilibria and perform some numerical simulations.
Gui-Quan Sun, Zhenguo Bai, Zi-Ke Zhang, Tao Zhou, Zhen Jin   +4 more
doaj   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source