Results 61 to 70 of about 556,638 (273)

Application of the type and target reproduction numbers to the evaluation of the influence of each prefecture in Japan on the disease spread

Infectious Disease Modelling
In this study, by applying population mobility data in July, August and September of 2019–2023 in Japan to a multigroup epidemic model, we calculate the type and target reproduction numbers of each prefecture in Japan. Regarding these values as a kind of
Toshikazu Kuniya
doaj   +1 more source

On the existence of a nontrivial equilibrium in relation to the basic reproductive number [PDF]

International Journal of Applied Mathematics and Computer Science, 2017
AbstractEquilibrium analysis in autonomous evolutionary models is of central importance for developing long term treatments. This task typically includes checks on the existence and stability of some equilibria. Prior to touching on the stability, one often attempts to determine the existence where the basic reproductive numberℛ0plays a critical role ...
Karunia Putra Wijaya, Sutimin, Edy Soewono, Thomas Götz   +3 more
openaire   +2 more sources

Estimation of the serial interval and basic reproduction number of COVID‐19 in Qom, Iran, and three other countries: A data‐driven analysis in the early phase of the outbreak

Transboundary and Emerging Diseases, 2020
The outbreak of COVID‐19 was first reported from China, and on 19 February 2020, the first case was confirmed in Qom, Iran. The basic reproduction number (R0) of infection is variable in different populations and periods. This study aimed to estimate the
Mohammad Aghaali, G. Kolifarhood, Roya Nikbakht, H. Mozafar Saadati, Seyed Saeed Hashemi Nazari   +4 more
semanticscholar   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

MODEL MATEMATIKA PENYEBARAN PENYAKIT PULMONARY TUBERCULOSIS DENGAN PENGGUNAAN MASKER MEDIS

Barekeng, 2020
This research developed a model of tuberculosis disease spread using the SIR model with addition of the medical mask usage factor. First, we create a diagram of the tuberculosis disease spread compartment through contact between individuals with medical ...
Nur Inayah, Muhammad Manaqib, Nina Fitriyati, Ikhwal Yupinto   +3 more
doaj   +1 more source

Mathematical Modeling for Hospitalization due to Temperature Variations [PDF]

International Journal of Mathematical, Engineering and Management Sciences, 2019
Sudden changes in temperature occur due to ecological disturbances which results into global warming, volcanic eruption, depletion of ozone layer etc. This has become a crucial environmental and social issue all over the world.
Nita H. Shah, Purvi M. Pandya, Moksha H. Satia, Foram A. Thakkar   +3 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Evaluating different epidemiological models with the identical basic reproduction number ℛ0

Journal of Biological Dynamics, 2020
Epidemiological models with the identical basic reproduction number $ \mathcal {R}_0 $ may behave differently on both short time scale and long time scale.
Fan Bai
doaj   +1 more source