Results 81 to 90 of about 1,552,390 (331)

Spatial variation in the basic reproduction number of COVID-19: A systematic review [PDF]

, 2020
Thiede R, Abdelatif N, Fabris-Rotelli I, Manjoo-Docrat R, Holloway J, Rensburg CJv, Debba P, Dudeni-Tlhone N, Kimmie Z, Roux Al.   +9 more
europepmc   +1 more source

Edge-based compartmental modelling of an SIR epidemic on a dual-layer static-dynamic multiplex network with tunable clustering [PDF]

, 2018
The duration, type and structure of connections between individuals in real-world populations play a crucial role in how diseases invade and spread. Here, we incorporate the aforementioned heterogeneities into a model by considering a dual-layer static ...
Barnard, Rosanna C, Berthouze, Luc, Kiss, Istvan Z, Miller, Joel C   +3 more
core   +3 more sources

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Transmission dynamics of the ongoing chikungunya outbreak in Central Italy. From coastal areas to the metropolitan city of Rome, summer 2017 [PDF]

, 2017
A large chikungunya outbreak is ongoing in Italy, with a main cluster in the Anzio coastal municipality. With preliminary epidemiological data, and a transmission model using mosquito abundance and biting rates, we estimated the basic reproduction number
Caputo, Beniamino, DELLA TORRE, Alessandra, Filipponi, Federico, Guzzetta, Giorgio, Manica, Mattia, Merler, Stefano, Poletti, Piero, Rosà, Roberto, Solimini, ANGELO GIUSEPPE   +8 more
core   +2 more sources

Basic Reproduction Number of Enterovirus 71 Coxsackievirus A16 and A6: Evidence from Outbreaks of Hand, Foot and Mouth Disease in China between 2011 and 2018.

Clinical Infectious Diseases, 2020
BACKGROUND Enterovirus 71 (EV-A71), Coxsackievirus A16 (CV-A16) and Coxsackievirus A6 (CV-A6) are common serotypes causing hand, foot, and mouth disease (HFMD).
Zhong Zhang, Yang Liu, Fengfeng Liu, M. Ren, Taoran Nie, J. Cui, Z. Chang, Z. Li   +7 more
semanticscholar   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

The basic reproduction number and prediction of the epidemic size of the novel coronavirus (COVID-19) in Shahroud, Iran

Epidemiology and Infection, 2020
The aim of this study was to estimate the basic reproduction number (R0) of COVID-19 in the early stage of the epidemic and predict the expected number of new cases in Shahroud in Northeastern Iran.
A. Khosravi, R. Chaman, M. Rohani-Rasaf, F. Zare, S. Mehravaran, M. Emamian   +5 more
semanticscholar   +1 more source

Estimating the Basic Reproductive Number from Viral Sequence Data [PDF]

Molecular Biology and Evolution, 2011
Epidemiological processes leave a fingerprint in the pattern of genetic structure of virus populations. Here, we provide a new method to infer epidemiological parameters directly from viral sequence data. The method is based on phylogenetic analysis using a birth-death model (BDM) rather than the commonly used coalescent as the model for the ...
Stadler, Tanja, Kouyos, Roger, von Wyl, Viktor, Yerly, Sabine, Böni, Jürg, Bürgisser, Philippe, Klimkait, Thomas, Joos, Beda, Rieder, Philip, Xie, Dong, Günthard, Huldrych F., Drummond, Alexei J., Bonhoeffer, Sebastian, Swiss HIV Cohort Study   +13 more
openaire   +5 more sources

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

SEIR epidemiological model with varying infectivity and infinite delay [PDF]

, 2008
A new SEIR model with distributed infinite delay is derived when the infectivity depends on the age of infection. The basic reproduction number R-0, which is a threshold quantity for the stability of equilibria, is calculated.
Röst, Gergely
core   +1 more source